Cellular mechanisms linking to outdoor and indoor air pollution damage during pregnancy

Delia I. Chiarello*, Javier Ustáriz, Reinaldo Marín, Ivo Carrasco-Wong, Marcelo Farías, Ady Giordano, Felipe S. Gallardo, Sebastián E. Illanes, Jaime Gutiérrez*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Pregnancies are a critical window period for environmental influences over the mother and the offspring. There is a growing body of evidence associating indoor and outdoor air pollution exposure to adverse pregnancy outcomes such as preterm birth and hypertensive disorders of pregnancy. Particulate matter (PM) could trigger oxi-inflammation and could also reach the placenta leading to placental damage with fetal consequences. The combination of strategies such as risk assessment, advise about risks of environmental exposures to pregnant women, together with nutritional strategies and digital solutions to monitor air quality can be effective in mitigating the effects of air pollution during pregnancy.

Original languageEnglish
Article number1084986
Pages (from-to)1084986
JournalFrontiers in Endocrinology
StatePublished - 2023

Bibliographical note

Copyright © 2023 Chiarello, Ustáriz, Marín, Carrasco-Wong, Farías, Giordano, Gallardo, Illanes and Gutiérrez.


  • PM
  • cell damage
  • exposome
  • indoor - outdoor pollution
  • mitigation strategies
  • pregnancy


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