Carcinoma escamoso de nasofaringe localmente avanzado: actualización en el manejo y rol de la quimioterapia de inducción

Felipe Carvajal; Gustavo Luyo; Javier Veloso; Marcelo Veloso; Freddy Alarcón; Eduardo Villa; Erika Saavedra

doi:10.4067/s0034-98872023000901221

Carcinoma escamoso de nasofaringe localmente avanzado: actualización en el manejo y rol de la quimioterapia de inducción

Translated title of the contribution: Advances in Nasopharyngeal Carcinoma Treatment: Induction Chemotherapy and Concomitant Radio-Chemotherapy

Felipe Carvajal^*, Gustavo Luyo, Javier Veloso, Marcelo Veloso, Freddy Alarcón, Eduardo Villa, Erika Saavedra

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

Squamous cell carcinoma of the nasopharynx is responsible for 0.7% of all malignant tumors worldwide, with the highest incidence in the population of southern China and Southeast Asia. The standard treatment for locally advanced disease consists of a combination of radiotherapy and chemotherapy in different schedules. Among them, induction chemotherapy followed by concomitant radio-chemotherapy has shown in recent years to be a standard therapeutic option with high rates of locoregional control and overall survival. This paper aims to review the current evidence related to treatment with induction chemotherapy and subsequent radio-chemotherapy in nasopharyngeal cancer, its effectiveness, and the technical aspects of its applicability.

Translated title of the contribution	Advances in Nasopharyngeal Carcinoma Treatment: Induction Chemotherapy and Concomitant Radio-Chemotherapy
Original language	Spanish
Pages (from-to)	1221-1232
Number of pages	12
Journal	Revista Medica de Chile
Volume	151
Issue number	9
DOIs	https://doi.org/10.4067/s0034-98872023000901221
State	Published - Sep 2023

Bibliographical note

Publisher Copyright:
© 2023 Sociedad Medica de Santiago. All rights reserved.

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10.4067/s0034-98872023000901221

Cite this

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title = "Carcinoma escamoso de nasofaringe localmente avanzado: actualizaci{\'o}n en el manejo y rol de la quimioterapia de inducci{\'o}n",

abstract = "Squamous cell carcinoma of the nasopharynx is responsible for 0.7\% of all malignant tumors worldwide, with the highest incidence in the population of southern China and Southeast Asia. The standard treatment for locally advanced disease consists of a combination of radiotherapy and chemotherapy in different schedules. Among them, induction chemotherapy followed by concomitant radio-chemotherapy has shown in recent years to be a standard therapeutic option with high rates of locoregional control and overall survival. This paper aims to review the current evidence related to treatment with induction chemotherapy and subsequent radio-chemotherapy in nasopharyngeal cancer, its effectiveness, and the technical aspects of its applicability.",

keywords = "Chemoradiotherapy, Drug Therapy, Nasopharyngeal Carcinoma, Radiotherapy",

author = "Felipe Carvajal and Gustavo Luyo and Javier Veloso and Marcelo Veloso and Freddy Alarc{\'o}n and Eduardo Villa and Erika Saavedra",

year = "2023",

month = sep,

doi = "10.4067/s0034-98872023000901221",

language = "Spanish",

volume = "151",

pages = "1221--1232",

journal = "Revista Medica de Chile",

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}

TY - JOUR

T1 - Carcinoma escamoso de nasofaringe localmente avanzado

T2 - actualización en el manejo y rol de la quimioterapia de inducción

AU - Carvajal, Felipe

AU - Luyo, Gustavo

AU - Veloso, Javier

AU - Veloso, Marcelo

AU - Alarcón, Freddy

AU - Villa, Eduardo

AU - Saavedra, Erika

PY - 2023/9

Y1 - 2023/9

N2 - Squamous cell carcinoma of the nasopharynx is responsible for 0.7% of all malignant tumors worldwide, with the highest incidence in the population of southern China and Southeast Asia. The standard treatment for locally advanced disease consists of a combination of radiotherapy and chemotherapy in different schedules. Among them, induction chemotherapy followed by concomitant radio-chemotherapy has shown in recent years to be a standard therapeutic option with high rates of locoregional control and overall survival. This paper aims to review the current evidence related to treatment with induction chemotherapy and subsequent radio-chemotherapy in nasopharyngeal cancer, its effectiveness, and the technical aspects of its applicability.

AB - Squamous cell carcinoma of the nasopharynx is responsible for 0.7% of all malignant tumors worldwide, with the highest incidence in the population of southern China and Southeast Asia. The standard treatment for locally advanced disease consists of a combination of radiotherapy and chemotherapy in different schedules. Among them, induction chemotherapy followed by concomitant radio-chemotherapy has shown in recent years to be a standard therapeutic option with high rates of locoregional control and overall survival. This paper aims to review the current evidence related to treatment with induction chemotherapy and subsequent radio-chemotherapy in nasopharyngeal cancer, its effectiveness, and the technical aspects of its applicability.

KW - Chemoradiotherapy

KW - Drug Therapy

KW - Nasopharyngeal Carcinoma

KW - Radiotherapy

UR - https://www.scopus.com/pages/publications/85200427574

U2 - 10.4067/s0034-98872023000901221

DO - 10.4067/s0034-98872023000901221

M3 - Review article

C2 - 39093159

AN - SCOPUS:85200427574

SN - 0034-9887

VL - 151

SP - 1221

EP - 1232

JO - Revista Medica de Chile

JF - Revista Medica de Chile

IS - 9

ER -

Carcinoma escamoso de nasofaringe localmente avanzado: actualización en el manejo y rol de la quimioterapia de inducción

Abstract

Bibliographical note

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