Abstract
Objective
To describe changes in periodontal clinical status of patients according to systemic statin use prescribed by a cardiologist.
Material and methods
A descriptive study was performed on patients with chronic periodontitis referred from the Department of Cardiovascular Diseases of Dávila Clinic. A group of them began statin therapy. Clinical measurements of periodontal probing depth (PD), clinical attachment level, bleeding index, periodontal inflamed surface area, and gingival index, were performed at baseline (before starting statin therapy) and 6 months later. Data were analyzed using descriptive statistics.
Results
A total of 10 patients participated in the study, and five of them received statin therapy. The statin group compared to the group without statins, showed a mean decrease in: PD (0.4 mm versus 0.13 mm); percentage of PS sites ≥ 5 mm (4.16% versus 1.09%); clinical attachment level (0.5 mm versus 0.2 mm), bleeding index (27.16% versus 8.8%), and periodontal inflamed surface area (305.68 versus 121.35 mm2).
Conclusions
These results suggest that patients with chronic periodontitis may benefit from systemic therapy with statins. Randomized clinical trials with optimal sample size are required to check the effect and impact of statins on the periodontal status.
To describe changes in periodontal clinical status of patients according to systemic statin use prescribed by a cardiologist.
Material and methods
A descriptive study was performed on patients with chronic periodontitis referred from the Department of Cardiovascular Diseases of Dávila Clinic. A group of them began statin therapy. Clinical measurements of periodontal probing depth (PD), clinical attachment level, bleeding index, periodontal inflamed surface area, and gingival index, were performed at baseline (before starting statin therapy) and 6 months later. Data were analyzed using descriptive statistics.
Results
A total of 10 patients participated in the study, and five of them received statin therapy. The statin group compared to the group without statins, showed a mean decrease in: PD (0.4 mm versus 0.13 mm); percentage of PS sites ≥ 5 mm (4.16% versus 1.09%); clinical attachment level (0.5 mm versus 0.2 mm), bleeding index (27.16% versus 8.8%), and periodontal inflamed surface area (305.68 versus 121.35 mm2).
Conclusions
These results suggest that patients with chronic periodontitis may benefit from systemic therapy with statins. Randomized clinical trials with optimal sample size are required to check the effect and impact of statins on the periodontal status.
Translated title of the contribution | Changes in clinic periodontal status according to systemic statins intake |
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Original language | Spanish |
Pages (from-to) | 111-116 |
Journal | Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral |
Volume | 8 |
Issue number | 2 |
Early online date | 13 May 2015 |
DOIs | |
State | Published - 15 Aug 2015 |
Bibliographical note
Copyright © 2014 Sociedad de Periodoncia de Chile, Sociedad de Implantología Oral de Chile y Sociedad de Prótesis y Rehabilitación Oral de Chile. Published by Elsevier España S.L.Keywords
- Periodontitis
- Statins
- Cardiology