Calcifications may be a frequent finding in mucoepidermoid carcinomas of the salivary glands: a clinicopathologic study

Wilfredo Alejandro González-Arriagada; Alan Santos-Silva; Fabio Augusto Ito; Pablo Vargas; Márcio Ajudarte Lopes

doi:10.1016/j.tripleo.2010.10.022

Calcifications may be a frequent finding in mucoepidermoid carcinomas of the salivary glands: a clinicopathologic study

Wilfredo Alejandro González-Arriagada, Alan Santos-Silva, Fabio Augusto Ito, Pablo Vargas, Márcio Ajudarte Lopes^*

^*Corresponding author for this work

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17 Scopus citations

Abstract

Calcifications in mucoepidermoid carcinoma (MEC) of the salivary glands are considered to be exceptionally rare and are often associated with high-grade tumors. This study reviewed 30 cases of MECs to access the frequency of calcifications and the clinical profile of the patients and histopathologic aspects of the tumors. In total, 6 cases of calcifications (20%) were identified. Five patients were women and 1 was a man, patients' ages ranged from 22 to 69 years old, and calcifications were found in conventional and clear celltype MECs. Areas of calcification showed positivity for periodic acidSchiff and mucicarmine, supporting the hypothesis that they originate from the precipitation of mucous secretion. The presence of calcifications in MECs was independent of the histologic grade of the tumors and the histopathologic variants. Calcifications in salivary MECs may not be as rare as previously mentioned in the literature and may be not associated with high-grade tumors.

Original language	English
Pages (from-to)	482-485
Number of pages	4
Journal	Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Volume	111
Issue number	4
DOIs	https://doi.org/10.1016/j.tripleo.2010.10.022
State	Published - Apr 2011
Externally published	Yes

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10.1016/j.tripleo.2010.10.022

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@article{b40bda2547ac462b81cdc09ce094288e,

title = "Calcifications may be a frequent finding in mucoepidermoid carcinomas of the salivary glands: a clinicopathologic study",

abstract = "Calcifications in mucoepidermoid carcinoma (MEC) of the salivary glands are considered to be exceptionally rare and are often associated with high-grade tumors. This study reviewed 30 cases of MECs to access the frequency of calcifications and the clinical profile of the patients and histopathologic aspects of the tumors. In total, 6 cases of calcifications (20%) were identified. Five patients were women and 1 was a man, patients' ages ranged from 22 to 69 years old, and calcifications were found in conventional and clear celltype MECs. Areas of calcification showed positivity for periodic acidSchiff and mucicarmine, supporting the hypothesis that they originate from the precipitation of mucous secretion. The presence of calcifications in MECs was independent of the histologic grade of the tumors and the histopathologic variants. Calcifications in salivary MECs may not be as rare as previously mentioned in the literature and may be not associated with high-grade tumors. ",

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author = "Gonz{\'a}lez-Arriagada, {Wilfredo Alejandro} and Alan Santos-Silva and Ito, {Fabio Augusto} and Pablo Vargas and {Ajudarte Lopes}, M{\'a}rcio",

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doi = "10.1016/j.tripleo.2010.10.022",

language = "English",

volume = "111",

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journal = "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology",

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Calcifications may be a frequent finding in mucoepidermoid carcinomas of the salivary glands: a clinicopathologic study. / González-Arriagada, Wilfredo Alejandro; Santos-Silva, Alan; Ito, Fabio Augusto et al.
In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol. 111, No. 4, 04.2011, p. 482-485.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Calcifications may be a frequent finding in mucoepidermoid carcinomas of the salivary glands

T2 - a clinicopathologic study

AU - González-Arriagada, Wilfredo Alejandro

AU - Santos-Silva, Alan

AU - Ito, Fabio Augusto

AU - Vargas, Pablo

AU - Ajudarte Lopes, Márcio

PY - 2011/4

Y1 - 2011/4

N2 - Calcifications in mucoepidermoid carcinoma (MEC) of the salivary glands are considered to be exceptionally rare and are often associated with high-grade tumors. This study reviewed 30 cases of MECs to access the frequency of calcifications and the clinical profile of the patients and histopathologic aspects of the tumors. In total, 6 cases of calcifications (20%) were identified. Five patients were women and 1 was a man, patients' ages ranged from 22 to 69 years old, and calcifications were found in conventional and clear celltype MECs. Areas of calcification showed positivity for periodic acidSchiff and mucicarmine, supporting the hypothesis that they originate from the precipitation of mucous secretion. The presence of calcifications in MECs was independent of the histologic grade of the tumors and the histopathologic variants. Calcifications in salivary MECs may not be as rare as previously mentioned in the literature and may be not associated with high-grade tumors.

AB - Calcifications in mucoepidermoid carcinoma (MEC) of the salivary glands are considered to be exceptionally rare and are often associated with high-grade tumors. This study reviewed 30 cases of MECs to access the frequency of calcifications and the clinical profile of the patients and histopathologic aspects of the tumors. In total, 6 cases of calcifications (20%) were identified. Five patients were women and 1 was a man, patients' ages ranged from 22 to 69 years old, and calcifications were found in conventional and clear celltype MECs. Areas of calcification showed positivity for periodic acidSchiff and mucicarmine, supporting the hypothesis that they originate from the precipitation of mucous secretion. The presence of calcifications in MECs was independent of the histologic grade of the tumors and the histopathologic variants. Calcifications in salivary MECs may not be as rare as previously mentioned in the literature and may be not associated with high-grade tumors.

KW - Of-the-literature

KW - Palate

KW - Tumors

U2 - 10.1016/j.tripleo.2010.10.022

DO - 10.1016/j.tripleo.2010.10.022

M3 - Article

SN - 2212-4403

VL - 111

SP - 482

EP - 485

JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

IS - 4

ER -

Calcifications may be a frequent finding in mucoepidermoid carcinomas of the salivary glands: a clinicopathologic study

Abstract

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