Biocompatibility and safety of a hybrid core-shell nanoparticulate OP-1 delivery system intramuscularly administered in rats

Keyphrases

• Delivery System 100%
• Biocompatibility 100%
• OP-1 100%
• Nanoparticulate 100%
• Intramuscularly 100%
• Injection Site 100%
• Hybrid Core-shell 100%
• Young Males 50%
• Inflammation 50%
• Monodisperse 50%
• Bioactive 50%
• Natural Polyelectrolytes 50%
• Alternating Layers 50%
• Controlled Delivery System 50%
• Blood Samples 50%
• Adverse Reactions 50%
• Body Weight Changes 50%
• Treatment Duration 50%
• Growth Factors 50%
• Extended Shelf Life 50%
• Immune Response 50%
• Cationic Nanoparticles 50%
• Organ Function 50%
• MC3T3 50%
• Hematology Analyzer 50%
• Osteogenic Proteins 50%
• Wistar Rats 50%
• Cell Viability 50%
• Health Effects 50%
• In Vitro Biocompatibility 50%
• Nanoparticles 50%
• Biochemical Analysis 50%
• Mouse Preosteoblasts 50%
• Major Organs 50%
• No Adverse Effect 50%
• Biomolecules 50%
• Nanoparticulate System 50%
• Liposomal 50%
• Bone Growth Factors 50%
• Pathological Changes 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Adverse Event 100%
• Nanoparticle 100%
• Biocompatibility 100%
• Growth Factor 100%
• Inflammation 50%
• Polyelectrolyte 50%
• Controlled Release 50%
• Cell Viability 50%
• Osteogenic Protein 1 50%
• Wistar Rat 50%