Beta-thromboglobulin during normal pregnancy, labor, and puerperium

Roberto Romero, Edward Snyder, David Scott, Enrique Oyarzun, John C. Hobbins, Thomas P. Duffy

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Platelet activation has been implicated in the pathogenesis of several obstetrical conditions such as preeclampsia and intrauterine growth retardation. Plasma beta-thromboglobulin (BTG) concentration is an index of in vivo platelet activation. The purpose of this study was to establish normal values of plasma BTG during pregnancy, labor and puerperium. Plasma BTG concentrations were determined from 121 uncomplicated pregnant women, 20 women in labor, 20 puerperal women, and a control group of 28 healthy non-pregnant volunteers. There was no significant difference in plasma BTG concentrations between non-pregnant and pregnant women. Gestational age, labor, and puerperium did not affect plasma BTG concentrations.
Original languageAmerican English
Pages (from-to)109-112
Number of pages4
JournalAmerican Journal of Perinatology
Issue number2
StatePublished - 1 Jan 1988
Externally publishedYes

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