A novel biomaterial based on salmon-gelatin and its in vivo evaluation as sterile wound-dressing

Javier Enrione; Karina Pino; Marzena Pepczynska; Donald I. Brown; Rina Ortiz; Elizabeth Sánchez; Cristian A. Acevedo

doi:10.1016/j.matlet.2017.10.049

A novel biomaterial based on salmon-gelatin and its in vivo evaluation as sterile wound-dressing

Javier Enrione, Karina Pino, Marzena Pepczynska, Donald I. Brown, Rina Ortiz, Elizabeth Sánchez, Cristian A. Acevedo^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A novel porous biomaterial based on salmon-gelatin and excipients was developed. The biomaterial was sterilized using gamma radiation. Mechanical and structural properties were studied. The biomaterial was used as wound-dressing in an animal model for four weeks. The in vivo results show biosafety of the biomaterial and high potential for clinical application in patients with tissue regeneration requirements.

Original language	English
Pages (from-to)	159-164
Number of pages	6
Journal	Materials Letters
Volume	212
DOIs	https://doi.org/10.1016/j.matlet.2017.10.049
State	Published - 1 Feb 2018

Bibliographical note

Funding Information:
The authors acknowledge the research funding from PMI Grant UAN1303, Conicyt by Basal Centre CCTVaL FB0821 and Postdoc Grant FAI UANDES N o FCH-PD-2015-1 .

Publisher Copyright:
© 2017

Keywords

Biomaterials
Polymeric composites
Polymers
Porous materials

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10.1016/j.matlet.2017.10.049

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title = "A novel biomaterial based on salmon-gelatin and its in vivo evaluation as sterile wound-dressing",

abstract = "A novel porous biomaterial based on salmon-gelatin and excipients was developed. The biomaterial was sterilized using gamma radiation. Mechanical and structural properties were studied. The biomaterial was used as wound-dressing in an animal model for four weeks. The in vivo results show biosafety of the biomaterial and high potential for clinical application in patients with tissue regeneration requirements.",

keywords = "Biomaterials, Polymeric composites, Polymers, Porous materials",

author = "Javier Enrione and Karina Pino and Marzena Pepczynska and Brown, \{Donald I.\} and Rina Ortiz and Elizabeth S{\'a}nchez and Acevedo, \{Cristian A.\}",

note = "Funding Information: The authors acknowledge the research funding from PMI Grant UAN1303, Conicyt by Basal Centre CCTVaL FB0821 and Postdoc Grant FAI UANDES N o FCH-PD-2015-1 . Publisher Copyright: {\textcopyright} 2017",

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doi = "10.1016/j.matlet.2017.10.049",

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T1 - A novel biomaterial based on salmon-gelatin and its in vivo evaluation as sterile wound-dressing

AU - Enrione, Javier

AU - Pino, Karina

AU - Pepczynska, Marzena

AU - Brown, Donald I.

AU - Ortiz, Rina

AU - Sánchez, Elizabeth

AU - Acevedo, Cristian A.

N1 - Funding Information: The authors acknowledge the research funding from PMI Grant UAN1303, Conicyt by Basal Centre CCTVaL FB0821 and Postdoc Grant FAI UANDES N o FCH-PD-2015-1 . Publisher Copyright: © 2017

PY - 2018/2/1

Y1 - 2018/2/1

N2 - A novel porous biomaterial based on salmon-gelatin and excipients was developed. The biomaterial was sterilized using gamma radiation. Mechanical and structural properties were studied. The biomaterial was used as wound-dressing in an animal model for four weeks. The in vivo results show biosafety of the biomaterial and high potential for clinical application in patients with tissue regeneration requirements.

AB - A novel porous biomaterial based on salmon-gelatin and excipients was developed. The biomaterial was sterilized using gamma radiation. Mechanical and structural properties were studied. The biomaterial was used as wound-dressing in an animal model for four weeks. The in vivo results show biosafety of the biomaterial and high potential for clinical application in patients with tissue regeneration requirements.

KW - Biomaterials

KW - Polymeric composites

KW - Polymers

KW - Porous materials

UR - https://www.scopus.com/pages/publications/85032032655

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DO - 10.1016/j.matlet.2017.10.049

M3 - Article

AN - SCOPUS:85032032655

SN - 0167-577X

VL - 212

SP - 159

EP - 164

JO - Materials Letters

JF - Materials Letters

ER -

A novel biomaterial based on salmon-gelatin and its in vivo evaluation as sterile wound-dressing

Abstract

Bibliographical note

Keywords

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