Project Details


The hydroxyacids 3-hydroxybutyrate and 2-hydroxyisobutyrate are chiral molecules that can be used as intermediates in the synthesis of high value products such as hormones, antibiotics and drugs. R. eutropha and A. lata were selected as the chassis for the production of these hydroxy acids because the accumulation of PHB in these organisms occurs at high rates as a non-growth and growth associated product, respectively, and PHB production as well as (R)-3-hydroxybutyryl-CoA and acetyl-CoA are regulated at the enzyme level by the availability of NAD(P)H
Short titleFONDECYT Regular 1211434
Effective start/end date1/03/211/03/25


  • National Agency for Research and Development (ANID): CLP197,816,000.00

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 9 - Industry, Innovation, and Infrastructure
  • SDG 13 - Climate Action