Projects per year
Personal profile
Research Interests
My research interest has been focused on the study of the regenerative and immunosuppresive abilites of mesenchymal stem cells (MSC). Particularly in the last few years I have been studying the interaction of MSCs with cellls from the immune system particularly with pro-inflammatory Thelper 1 and Thelper17 lymphocytes. Currently our research team is dedicated to evaluating the role of metabolism in the immunosuppressive and regenerative properties of MSCs and their extracellular derivatives including small microvesicles enriched in exosomes using murine models of diseases such as osteoarthritis, graft versus host disease, arthritis induced by collagen.
External positions
Investigador postdoctoral en la Unite Inserm 1183 en Montpellier, Francia., INSTITUT OF REGENERATIVE MEDICINE AND BIOTHERAPIES (IRMB), UNITE INSERM 1183, MONTPELLIER, FRANCE
16 Jan 2013 → 9 Jul 2016Fingerprint
Dive into the research topics where Patricia Alejandra Luz Crawford is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
Research output
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HIF1α-dependent metabolic reprogramming governs mesenchymal stem/stromal cell immunoregulatory functions
Contreras-Lopez, R., Elizondo-Vega, R., Paredes, M. J., Luque-Campos, N., Torres, M. J., Tejedor, G., Vega-Letter, A. M., Figueroa-Valdés, A., Pradenas, C., Oyarce, K., Jorgensen, C., Khoury, M., Garcia-Robles, M. D. L. A., Altamirano, C., Djouad, F. & Luz-Crawford, P., 1 Jun 2020, In: FASEB Journal. 34, 6, p. 8250-8264 15 p.Research output: Contribution to journal › Article › peer-review
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Inhibition of Hypothalamic MCT4 and MCT1–MCT4 Expressions Affects Food Intake and Alters Orexigenic and Anorexigenic Neuropeptide Expressions
Elizondo-Vega, R., Oyarce, K., Salgado, M., Barahona, M. J., Recabal, A., Ordenes, P., López, S., Pincheira, R., Luz-Crawford, P. & García-Robles, M. A., 1 Feb 2020, In: Molecular Neurobiology. 57, 2, p. 896-909 14 p.Research output: Contribution to journal › Article › peer-review
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Mechanisms behind the Immunoregulatory Dialogue between Mesenchymal Stem Cells and Th17 Cells
Terraza-Aguirre, C., Campos-Mora, M., Elizondo-Vega, R., Contreras-López, R. A., Luz-Crawford, P., Jorgensen, C. & Djouad, F., 10 Jul 2020, In: Cells. 9, 7Research output: Contribution to journal › Scientific review › peer-review
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Mitochondrial transfer from MSCs to T cells induces Treg differentiation and restricts inflammatory response
Court, A. C., Le-Gatt, A., Luz-Crawford, P., Parra, E., Aliaga-Tobar, V., Bátiz, L. F., Contreras, R. A., Ortúzar, M. I., Kurte, M., Elizondo-Vega, R., Maracaja-Coutinho, V., Pino-Lagos, K., Figueroa, F. E. & Khoury, M., 5 Feb 2020, In: EMBO Reports. 21, 2Research output: Contribution to journal › Article › peer-review
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PPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties
Contreras-Lopez, R. A., Elizondo-Vega, R., Torres, M. J., Vega-Letter, A. M., Luque-Campos, N., Paredes-Martinez, M. J., Pradenas, C., Tejedor, G., Oyarce, K., Salgado, M., Jorgensen, C., Khoury, M., Kronke, G., Garcia-Robles, M. A., Altamirano, C., Luz-Crawford, P. & Djouad, F., 1 Dec 2020, In: Scientific Reports. 10, 1Research output: Contribution to journal › Article › peer-review