Projects per year
Personal profile
Professional Information
He obtained a Ph.D. in health and biology from the University of Montpellier, France, focusing on gene therapy in joint diseases, where a constellation of gene therapy strategies were used included RNA interference, viral- and liposome-based vectors. The successful outcome of these approaches resulted in multiple high impact publications, conveying the opportunity for a postdoctoral position at the MIT, Koch Institute, Cambridge, Massachusetts. At MIT, he focused his effort on establishing a humanized mouse model; a mouse with a human blood system. This was followed by a position at the MIT-Singapore alliance for research and technology (SMART), in Singapore, where he worked on hematopoietic and fetal stem cells. Following this enriching experience, he established his own research laboratory of nanoRegenerative medicine, in Santiago de Chile, where he currently directs a young team of highly motivated researchers. The laboratory is located at the Universidad de Los Andes and affiliated to a biotechnology venture, Cells for Cells, where he currently hold a dual position as an A/Professor and Chief Scientific Officer (CSO) at Cells for Cells and Regenero (co-founder), the Chilean consortium for Regenerative medicine.
Research Interests
With a keen interest in bridging the bench work to the bedside, his team is carrying out research with the objective of developing treatments and therapeutics against diseases of public health and economic importance that are impacting the daily life of people living in Chile. This vanguard expertise was capitalized in several clinical application in diseases with unmet medical needs such as heart failure, Osteoarthritis, lupus and pulpitis.
External positions
Chief Scientific Officer, Cells for Cells
9 Jun 2011 → …
Open Keywords
- cell therapy
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL
Cuenca, J., Alcayaga-Miranda, F., Khoury, M., Hidalgo, Y. & Kurte, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/04/21 → 31/03/25
Project: Research
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Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT)
Khoury, M., Alcayaga-Miranda, F., Cuenca, J., Acevedo, J. P., Figueroa, F., Luz Crawford, P. A., Wyneken, Ú., Illanes, S., Batiz, L. F., Busso, D., Busso, D., J. Monteiro, L., Nardocci, G., Enrione, J., Espinoza, F., Valenzuela Bravo, M. T. & Prieto, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/11/21 → 31/10/26
Project: Research
Research output
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A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells
Figueroa-Valdés, A. I., de la Fuente, C., Hidalgo, Y., Vega-Letter, A. M., Tapia-Limonchi, R., Khoury, M. & Alcayaga Miranda, F., 26 May 2021, In: Frontiers in Bioengineering and Biotechnology. 9, p. 619930 619930.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial: The Role of Metabolism in MSC-Mediated Immunomodulation
Pers, Y. M., Jorgensen, C. & Khoury, M., 26 Aug 2021, In: Frontiers in Immunology. 12, p. 751865 751865.Research output: Contribution to journal › Editorial
Open Access -
Mitochondria-Rich Fraction Isolated from Mesenchymal Stromal Cells Reduces Lung and Distal Organ Injury in Experimental Sepsis∗
De Carvalho, L. R. P., Abreu, S. C., De Castro, L. L., Andrade Da Silva, L. H., Silva, P. M., Vieira, J. B., Santos, R. T., Cabral, M. R., Khoury, M., Weiss, D. J., Lopes-Pacheco, M., Silva, P. L., Cruz, F. F. & Rocco, P. R. M., Sep 2021, In: Critical Care Medicine. 49, 9, p. E880-E890Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Musculoskeletal Progenitor/Stromal Cell-Derived Mitochondria Modulate Cell Differentiation and Therapeutical Function
Jorgensen, C. & Khoury, M., 8 Mar 2021, In: Frontiers in Immunology. 12, p. 606781 606781.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential
Contreras-Lopez, R., Elizondo-Vega, R., Luque-Campos, N., Torres, M. J., Pradenas, C., Tejedor, G., Paredes-Martínez, M. J., Vega-Letter, A. M., Campos-Mora, M., Rigual-Gonzalez, Y., Oyarce, K., Salgado, M., Jorgensen, C., Khoury, M., Garcia-Robles, M. D. L. Á., Altamirano, C., Djouad, F. & Luz-Crawford, P., 2021, In: Theranostics. 11, 1, p. 445-460 16 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations
Activities
- 2 Oral presentation
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Mesenchymal stem cell-transferred mitochondria elicit an immune function reprogramming that entails T regulatory cell commitment and clinical improvement of graft vs host disease
Angela C. Court (Speaker), Alice Le-Gatt (Keynote speaker), Patricia Alejandra Luz Crawford (Speaker), Victor Aliaga-Tobar (Speaker), Luis Federico Batiz (Speaker), Eliseo Parra (Speaker), Rafael Contreras (Speaker), María Ignacia Ortúzar (Speaker), Mónica Kurte (Speaker), Roberto Elizondo-Vega (Speaker), Vinicius Maracaja-Coutinho (Speaker), Karina Pino-Lagos (Speaker), Radmila Velarde (Speaker), Maroun Khoury (Speaker) & Fernando Figueroa (Speaker)
2019Activity: Talk or presentation › Oral presentation
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workshop de procedimientos de endodoncia regenerativa
Claudia Brizuela Cordero (Speaker) & Maroun Khoury (Speaker)
31 May 2018Activity: Talk or presentation › Oral presentation
Courses
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Avances en terapia celular
Patricia Alejandra Luz Crawford, Jimena Cuenca, Francisca Alcayaga-Miranda, Maroun Khoury & Juan Pablo Acevedo 13/08/21 → 17/12/21
Course
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DOCB1210 Avances Biotecnológicos en Medicina
Course
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Introduccion a la Medicina Regenerativa
Patricia Alejandra Luz Crawford, Maroun Khoury & Francisca Alcayaga-Miranda 11/03/21 → 16/07/21
Course
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INTRODUCCION A LA MEDICINA REGENERATIVA
Patricia Alejandra Luz Crawford, Francisca Alcayaga-Miranda & Maroun Khoury 14/08/20 → 18/12/20
Course
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TERAPIA CELULAR Y MEDICINA REGENERATIVA
Patricia Alejandra Luz Crawford, Francisca Alcayaga-Miranda, Maroun Khoury & Jimena Cuenca 14/08/18 → 21/12/18
Course
Press / Media
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US Patent Issued to Cells for Cells on June 22 for "Anti-angiogenic therapy based on exosomes derived from menstrual stem cells" (Chilean Inventors)
23/06/21
1 item of Media coverage
Press/Media
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VEINTIS™ the tissue-engineered vascular graft developed by Cells for Cells, wins the 2020 National Innovation Prize
Maroun Khoury & Juan Pablo Acevedo
13/11/20
1 item of Media coverage
Press/Media
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Australia Patent: Application for 'Anti-angiogenic therapy based on exosomes derived from menstrual stem cells' Lapses
16/10/20
1 item of Media coverage
Press/Media
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Australia Patent: Application for 'Treatment for infection composed of menstrual stem cells' Lapses
15/10/20
1 item of Media coverage
Press/Media