Personal profile
Professional Information
I studied Biochemistry at the University of Concepción, Chile. I obtained my Ph.D. in Sciences with a mention in Molecular, Cellular, and Neurosciences from the University of Chile. Subsequently, I carried out my first postdoctoral research at the Universidad Nacional Andrés Bello and a second at the Universidad Mayor, both in Chile. I am currently serving as an Associate Researcher in the Neuroscience Program at the Center for Biomedical Research and Innovation, Universidad de los Andes.
Research interests
We are interested in understanding the cellular and molecular mechanisms that regulate early neurodevelopment, with a particular focus on the effects of prenatal exposure to maternal distress on these processes. Currently, our work aims to explore the consequences of prenatal stress on temperament development and cognitive abilities, while also integrating efforts to identify biomarkers that may predict altered neurodevelopmental trajectories.
Teaching
Throughout my academic career, I have participated in undergraduate courses in Cell Biology and Genetics at Universidad Nacional Andrés Bello and Universidad Mayor.
Education/Academic qualification
PhD, Sciences with a mention in Molecular, Cellular, and Neurosciences, Universidad de Chile
2010 → 2015
University Degree, Biochemist, Universidad de Concepción
2004 → 2009
Keywords
- R Medicine (General)
Open Keywords
- Prenatal stress
- Neurodevelopment
- Biomarkers
- Temperament
Research Lines
- Research Lines
- Prenatal stress
- Neurodevelopment
- Biomarkers
- Temperament
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Collaborations and top research areas from the last five years
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FONDECYT INICIACIÓN - 11260962: PRENATAL MATERNAL DISTRESS AND CHILD NEURODEVELOPMENTAL AND TEMPERAMENT OUTCOMES: AI-DRIVEN EARLY PREDICTION BASED ON UMBILICAL CORD SEVS MOLECULAR BIOMARKERS.
Sánchez Rubio, M. E. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/26 → 31/03/29
Project: RESEARCH
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FONDECYT POSTDOCTORADO - 3160622 : REGULACIÓN EPIGENÉTICA EN LA FORMACIÓN Y MANTENIMIENTO DE LA MEMORIA
Van Zundert, B. (Sponsoring Researcher) & Sánchez Rubio, M. E. (Postdoctoral Researcher)
1/11/15 → 31/10/18
Project: RESEARCH
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Urban air pollution reduces H3K9me2/me3 in hippocampal and olfactory neurons, correlating with memory and social deficits
Jury-Garfe, N., Sánchez-Rubio, M., Nardocci, G., Mercado, C., Peña-Baeza, N., Ruiz-Rudolph, P., Montecino, M., Varela-Nallar, L. & van Zundert, B., 1 Oct 2025, In: Science of the Total Environment. 997, 180145.Research output: Contribution to journal › Article › peer-review
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FOXM1 Participates in Trophoblast Migration and Early Trophoblast Invasion: Potential Role in Blastocyst Implantation
Peñailillo, R., Velásquez, V., Acuña-Gallardo, S., García, F., Sánchez, M., Nardocci, G., Illanes, S. E. & Monteiro, L. J., Feb 2024, In: International Journal of Molecular Sciences. 25, 3, 1678.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Maternal stress during pregnancy alters circulating small extracellular vesicles and enhances their targeting to the placenta and fetus
Sánchez-Rubio, M., Abarzúa-Catalán, L., del Valle, A., Méndez-Ruette, M., Salazar, N., Sandoval, S., Sigala, J., Godoy, M. I., Luarte, A., Monteiro, L. J., Romero, R., Choolani, M. A., Wyneken, Ú., Illanes, S. E. & Bátiz, L. F., Dec 2024, In: Biological Research. 57, 1, p. 70 70.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43 A90V mutation display a mild reactive state and release polyP toxic to motoneurons
Rojas, F., Aguilar, R., Almeida, S., Fritz, E., Corvalán, D., Ampuero, E., Abarzúa, S., Garcés, P., Amaro, A., Diaz, I., Arredondo, C., Cortes, N., Sanchez, M., Mercado, C., Varela-Nallar, L., Gao, F. B., Montecino, M. & van Zundert, B., 2023, In: Frontiers in Cell and Developmental Biology. 11, 1226604.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Transcriptional and Histone Acetylation Changes Associated with CRE Elements Expose Key Factors Governing the Regulatory Circuit in the Early Stage of Huntington’s Disease Models
Arancibia-Opazo, S., Contreras-Riquelme, J. S., Sánchez, M., Cisternas-Olmedo, M., Vidal, R. L., Martin, A. J. M. & Sáez, M. A., Jul 2023, In: International Journal of Molecular Sciences. 24, 13, 10848.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations