Projects per year
Personal profile
Professional Information
I am a biologist and hold a Master's degree in Cellular Biology and Physiology from the University of Paris Cité, and a PhD in Medical Sciences from the Catholic University of Chile.
I completed postdoctoral studies at the European Center for the Study of Diabetes in Strasbourg, France, thanks to a prestigious Marie Skłodowska-Curie scholarship.
Upon my return to Chile, I joined the Universidad de los Andes, where I work as a research professor.
In 2023, I was awarded a Fondecyt Initiation project, which is carried out in the Periodontal Research Laboratory at the Center for Biomedical Research and Innovation.
Teaching
The teaching areas where I have worked have mainly been training students during their undergraduate and Master's theses, both in France (University of Strasbourg) and in Chile at the University of the Andes.
Research interests
My line of research is framed in inter-organ communication and the regulation of insulin secretion (integrative physiology).
As has been described in recent years, there is a complex coordination between different organs to regulate pancreatic beta function. Thus, different organs such as skeletal muscle, adipose tissue, liver and others such as the brain, intestine, bone intervene in the regulation of insulin secretion.
I worked during my doctoral thesis and postdoctoral studies studying the secretome of skeletal muscle – myokines and extracellular vesicles – and their role in insulin secretion.
Since 2022, I have been working in a periodontal research laboratory, studying the mechanisms that associate periodontitis with type 2 diabetes. In particular, studying extracellular vesicles obtained from the periodontium of patients with periodontitis and evaluating their function in an animal model to study the metabolic changes they produce in the pancreas.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Doctorate in Medical Sciences, Pontificia Universidad Católica de Chile
… → 2016
Master, Master’s in Cellular Biology, Physiology, and Pathology, Université Paris Cité
… → 2010
University Degree, Biologist, Université Paris Cité
… → 2008
External positions
Post Doctorate, Centro Europeo de Estudio de la Diabetes
2 Jan 2018 → 31 Dec 2020
Open Keywords
- Diabetes
- Extracellular Vesicles
- Periodontitis
Research Lines
- Research Lines
- Periodontitis
- Type 2 Diabetes Mellitus
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Collaborations and top research areas from the last five years
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FONDECYT INICIACIÓN - 11230418 : PERIODONTITIS-DERIVED EXTRACELLULAR VESICLES AS MEDIATORS IN THE DEVELOPMENT OF GESTATIONAL DIABETES MELLITUS, INDUCED BY SYSTEMIC INFLAMMATION AND IMPAIRMENT PANCREATIC INSULIN SECRETION
Mizgier, M. L. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
15/03/23 → 14/03/26
Project: RESEARCH
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FAI INSCRIPCION CONGRESO - APO-CG-2023-28: INCREASED GINGIVAL CREVICULAR FLUID EXTRACELLULAR VESICLES ARE INVOLVED IN THE CROSSTALK BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES
Mizgier, M. L. (Principal Investigator), Realini, O. (Co-Investigator), Bendek Viera, M. J. (Co-Investigator), Rojas Pérez, C. I. (Co-Investigator), Monje, S. (Co-Investigator), Figari, A. (Co-Investigator), Hernández, M. (Co-Investigator), Ramírez Lobos, V. (Co-Investigator), Illanes, S. (Co-Investigator), Busso, D. (Co-Investigator) & Chaparro, A. (Co-Investigator)
Universidad de los Andes Chile
4/09/23 → 30/12/23
Project: RESEARCH
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Diagnostic accuracy of bone-related biomarkers on peri-implantitis: potential of A-proliferation-inducing ligand
Chaparro, A., Ramírez, V., Bendek, M. J., Nart, J., Monje, A., Pascual, A., Rojas, C., Mizgier, M. L., Albers, D. & Beltrán, V., Dec 2025, In: BMC Oral Health. 25, 1, p. 1240 1240.Research output: Contribution to journal › Article › peer-review
Open Access -
Gestational Diabetes Shapes Gingival Crevicular lncRNA Expression in Early Pregnancy: A Prospective Cohort Study
Chaparro, A., Bendek, M. J., Mizgier, M. L., Ramírez, V., Nardocci, G. & Illanes, S. E., 2025, In: Journal of Periodontal Research.Research output: Contribution to journal › Letter › peer-review
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Proteomic Insights Into Gingival Crevicular Extracellular Vesicles in Periodontitis and Gestational Diabetes: An Exploratory Study
Mizgier, M. L., Nardocci, G., Ramírez, V., Bendek, M. J., Hernández, M., Rojas, C., Herrera, D., Kantarci, A., Kemp, M. W., Illanes, S. E. & Chaparro, A., Feb 2025, In: Journal of Clinical Periodontology. 52, 2, p. 225-236 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Unveiling the association between angiogenic imbalance in the gingival crevicular fluid in maternal periodontitis and spontaneous preterm birth
Albers, D., Bendek, M. J., Hernández, M., Prieto, D., Rojas, C., Mizgier, M. L., Hernández, P., Illanes, S. E. & Chaparro, A., 2025, In: Frontiers in Dental Medicine. 6, 1625995.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteomic Analysis of Salivary Extracellular Vesicles from COVID-19 Patients Reveals a Specific Anti-COVID-19 Response Protein Signature
Weber, L., Torres, A., Realini, O., Bendek, M. J., Mizgier, M. L., Brizuela, C., Herrera, D., González, F. E. & Chaparro, A., Apr 2024, In: International Journal of Molecular Sciences. 25, 7, p. 1-20 20 p., 3704.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations