Projects per year
Personal profile
Professional Information
He studied Medicine at the National University of Cuyo, Mendoza, Argentina. He obtained his MSc in Cellular Biology and his PhD in Cellular and Molecular Biology at the Austral University of Chile. He has completed pre and postdoctoral research stays in Argentina, Spain, Germany and the United States.
He has received the Best Doctoral Thesis Award from the Chilean Academy of Sciences and other national and international distinctions. Currently, he is Director of the Center for Biomedical Research and Innovation at the Universidad de los Andes.
Research interests
His research focuses on understanding the cellular and molecular mechanisms of neurodevelopment, focusing on the process of generating neurons during fetal development or neurogenesis. In this context, he has obtained funding from national and international agencies and has trained numerous undergraduate and graduate students, as well as training post-doctoral fellows.
Currently, his research group is focused on two lines of research:
- Understanding the cellular mechanisms underlying alterations in the neurogenic process and, consequently, neurodevelopmental disorders.
- Study the effects of maternal stress during pregnancy (prenatal stress) on fetal neurodevelopment and its postnatal consequences
Education/Academic qualification
PhD, Ciencias, Mención Biología Celular y Molecular, Universidad Austral de Chile
… → 2008
Award Date: 1 Jun 2008
Master, Ciencias, Mención Biología Celular, Universidad Austral de Chile
Award Date: 1 Jul 2003
University Degree, Médico, Universidad Nacional de Cuyo
Award Date: 13 May 1999
External positions
Member Comitee of Research, Universidad de los Andes Chile
2018 → …
Director, Center for Interdisciplinary Studies on the Nervous System (CISNe). Universidad Austral de Chile
2015 → 2016
Associate Professor, Universidad Austral de Chile
2013 → 2016
Director, Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso (CISNe)
2012 → 2014
Director, Programa Honors de Investigación de la Facultad de Medicina. Universidad Austral de Chile
2009 → 2016
Profesor Asistente, Universidad Austral de Chile
2008 → 2013
Ayudante (Categoría 1), Universidad Nacional de Cuyo
1999
Ayudante (Categoría 2), Universidad Nacional de Cuyo
1995 → 1998
Research Lines
- Research Lines
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FONDECYT REGULAR - 1251409: UPREGULATION OF FOXO3 ACTIVITY IN INTERNEURON PROGENITOR CELLS AS A PATHOGENIC MECHANISM LINKING PRENATAL STRESS AND NEURODEVELOPMENTAL DISORDERS
Batiz, L. F. (Principal Investigator) & Luarte Navarro, A. E. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/25 → 31/03/29
Project: RESEARCH
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IMPACT: CENTER OF INTERVENTIONAL MEDICINE FOR PRECISION AND ADVANCED CELLULAR THERAPY (IMPACT)
Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. L. (Associate Investigator)
Agencia Nacional de Investigación y Desarrollo
1/11/21 → 31/10/26
Project: INNOVACIÓN Y DESARROLLO
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Prenatal biomarkers for neurodevelopmental changes
Batiz, L. F. (Principal Investigator)
Project: RESEARCH
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FONDECYT REGULAR - 1211384: PRENATAL STRESS: MATERNAL ASTROCYTE-DERIVED EXTRACELLULAR VESICLES AS A NOVEL STRESS-TRANSFER MECHANISM CONTRIBUTING TO ADVERSE OFFSPRING NEURODEVELOPMENT
Batiz, L. F. (Principal Investigator), Nardocci, G. (Co-Investigator), Wyneken, Ú. (Co-Investigator), Illanes, S. (Co-Investigator), J. Monteiro, L. (Co-Investigator) & Caradeux, J. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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FONDECYT REGULAR - 1200693: BRAIN ASTROCYTE-DERIVED EXTRACELLULAR VESICLES PROMOTE PROTECTIVE TREG INDUCTION IN THE GALT AND RESTORE GUT TOLERANCE IN STRESSED RATS.
Wyneken, Ú. (Principal Investigator), Batiz, L. F. (Co-Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Batiz, L. F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/20 → 31/03/24
Project: RESEARCH
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Maternal exposure to a high-magnitude earthquake during pregnancy influences pre-reading skills in early childhood
Bátiz, L. F., Palmeiro-Silva, Y. K., Rice, G. E., Monteiro, L. J., Galaburda, A. M., Romero, R., Choolani, M. A., Wyneken, U., Orellana, P. & Illanes, S. E., Dec 2021, In: Scientific Reports. 11, 1, p. 9244 9244.Research output: Contribution to journal › Article › peer-review
Open Access -
The Impact of Estrogen and Estrogen-Like Molecules in Neurogenesis and Neurodegeneration: Beneficial or Harmful?
Bustamante-Barrientos, F. A., Méndez-Ruette, M., Ortloff, A., Luz-Crawford, P., Rivera, F. J., Figueroa, C. D., Molina, L. & Bátiz, L. F., 8 Mar 2021, In: Frontiers in Cellular Neuroscience. 15, p. 636176 636176.Research output: Contribution to journal › Article › peer-review
Open Access -
Pleiotropic effects of alpha-SNAP M105I mutation on oocyte biology: ultrastructural and cellular changes that adversely affect female fertility in mice
de Paola, M., Miró, M. P., Ratto, M., Bátiz, L. F. & Michaut, M. A., 1 Dec 2019, In: Scientific Reports. 9, 1, 17374.Research output: Contribution to journal › Article › peer-review
Open Access -
Role of adherens junctions and apical-basal polarity of neural stem/progenitor cells in the pathogenesis of neurodevelopmental disorders: a novel perspective on congenital Zika syndrome
Bustamante, F. A., Miró, M. P., VelÁsquez, Z. D., Molina, L., Ehrenfeld, P., Rivera, F. J. & Bátiz, L. F., Aug 2019, In: Translational Research. 210, p. 57-79 23 p.Research output: Contribution to journal › Review article › peer-review
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α-SNAP is expressed in mouse ovarian granulosa cells and plays a key role in folliculogenesis and female fertility
Arcos, A., Paola, M. D., Gianetti, D., Acuña, D., Velásquez, Z. D., Miró, M. P., Toro, G., Hinrichsen, B., Muñoz, R. I., Lin, Y., Mardones, G. A., Ehrenfeld, P., Rivera, F. J., Michaut, M. A. & Batiz, L. F., 1 Dec 2017, In: Scientific Reports. 7, 1, 11765.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
Activities
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Universidad de Helsinki
Oyarce Pezoa, S. A. (Estudiante visitante) & Batiz, L. F. (Supervisor)
2024Activity: Visiting an external institution › Visita de un estudiante a una institución académica externa
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Universidad de Montreal
Méndez Ruette, M. (Estudiante visitante) & Batiz, L. F. (Supervisor)
3 Apr 2023 → 1 May 2023Activity: Visiting an external institution › Visita de un estudiante a una institución académica externa
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The role of alpha-SNAP in the biology of neural progenitor cells and neurogenesis: Understanding the pathophysiology of congenital hydrocephalus
Batiz, L. F. (Invited speaker)
2021Activity: Talk or presentation › Invited talk
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Astrocyte-derived EVs as a novel mediator of maternal stress transfer to the fetus
Batiz, L. F. (Invited speaker)
25 Aug 2021Activity: Talk or presentation › Invited talk
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The M105I mutation of alpha-SNAP leads to increased levels of pAMPK affecting the mitochondrial homeostasis and the balance between proliferation and differentiation of neural stem/progenitor cells
Henzi, R. (Keynote speaker), Bustamante, F. A. (Speaker), Méndez, M. (Speaker), Wyneken, Ú. (Speaker) & Batiz, L. F. (Speaker)
2021Activity: Talk or presentation › Oral presentation
Courses
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DOCB1110 Biología Celular y Molecular en Biomedicina
J. Monteiro, L., Nardocci, G., Batiz, L. F., Busso, D., Acevedo, J. P., Luz Crawford, P. A. & Wyneken, Ú. 22/03/21 → 30/06/21
Course
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DOCB1210 Avances Biotecnológicos en Medicina
J. Monteiro, L., Contardo, I., Nardocci, G., Acevedo, J. P., Khoury, M., Figueroa, F., Luz Crawford, P. A., Pino-Lagos, K., Wyneken, Ú., Alcayaga-Miranda, F., Enrione, J., Irarrazabal Muñoz, C. E., Illanes, S., Batiz, L. F., Chaparro, A., Haidar, Z. S., Díaz Calderón, P. & Sadarangani Khainey, A. P. 2/08/21 → …
Course
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DOCB3364 Tópicos Avanzados en Biomedicina: Contenido Optativo
J. Monteiro, L., Busso, D., Illanes, S., Batiz, L. F., Chaparro, A. & Monckeberg, M. 20/08/20 → 14/12/20
Course