Projects per year
Personal profile
Professional Information
She studied Biochemistry at the Universidad de Chile, Chile. Then she moved to Madrid, Spain, where she did a PhD in Biochemistry and Molecular Biology, at the Universidad Complutense de Madrid (UCM). Currently she works as a Professor and researcher at the Faculty of Medicine of the Universidad de los Andes, as well as holding a position as a researcher at Cells for Cells and Regenero, the Chilean Regenerative Medicine Consortium.
Research interests
Dr. Cuenca belongs to the Laboratory of Nano-Regenerative Medicine, located in the Center for Biomedical Research and Innovation (CIIB), investigating the therapeutic effect of mesenchymal/stromal stem cells (MSCs) in the treatment of different inflammatory pathologies such as acute respiratory distress syndrome (ARDS), sepsis or wound healing.
Research lines: Cell Therapy; Immunomodulatory effects of Mesenchymal Stem Cells; Autoimmune Diseases; Mechanisms in Autoimmune Diseases; Inflammation/miRNA; Molecular and Cellular Biology; Bioprocessing and Cellular Manufacturing
Teaching
La Dra. Jimena Cuenca ha impartido docencia en los siguientes cursos:
2012-2 Docente Troncal 1 “Biología celular y molecular en medicina”
2013-2 Docente Troncal 1 “Biología celular y molecular en medicina”
2015-2 Docente Troncal 1 “Biología celular y molecular en medicina”
2018-2 Docente Troncal 2 “Avances biotecnológicos en medicina”
2019-1 Docente Troncal 1 “Biología celular y molecular en medicina”
2022-2 Docente Troncal 2 “Avances biotecnológicos en medicina”
2023-2 Docente Troncal 2 “Avances biotecnológicos en medicina”
2024-2 Docente Troncal 2 “Avances biotecnológicos en medicina”
Education/Academic qualification
PhD, Bioquímica y Biología Molecular, Universidad Complutense de Madrid
… → 2006
University Degree, Bioquímico, Universidad de Chile
External positions
Evaluador en ANID (Comité de Biotenología), Agencia Nacional de Investigación y Desarrollo
Habilitación para la dirección de tesis doctorales
- Habilitado
Research Lines
- Research Lines
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FONDECYT POSTDOCTORADO - 3230447: TRASPLANTE DE MITOCONDRIAS RESISTENTES A LA HIPOXIA: UNA PROMETEDORA TERAPIA CONTRA LA HIPERTENSIÓN PULMONAR HIPÓXICA
Cuenca, J. (Sponsoring Researcher) & Castillo, S. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo
15/04/23 → 14/04/26
Project: RESEARCH
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IMPACT: CENTER OF INTERVENTIONAL MEDICINE FOR PRECISION AND ADVANCED CELLULAR THERAPY
Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. L. (Associate Investigator)
Agencia Nacional de Investigación y Desarrollo
1/11/21 → 31/10/26
Project: RESEARCH
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FONDEF IDEA I+D - 23I10325: DESARROLLO DE UN PRODUCTO ALOGÉNICO BASADO EN UN HIDROGEL BIOACTIVO CON NANOVESÍCULAS EXTRACELULARES Y SU VALIDACIÓN COMO TRATAMIENTO ENDODÓNTICO REGENERATIVO
Cuenca, J. (Director), Brizuela Cordero, C. I. (Alternate Director), Khoury, M. (Co-Investigator), Alcayaga-Miranda, F. (Co-Investigator), Canedo Marroquin, G. (Co-Investigator) & González-Arriagada, W. A. (Co-Investigator)
National Agency for Research and Development (ANID)
15/06/23 → 15/06/25
Project: INNOVACIÓN Y DESARROLLO
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FONDEFf IDEA I+D - IT21l0080: Biomanufacturing of Tissue Engineered Vascular Access for Hemodialysis
Acevedo, J. P. (Principal Investigator) & Cuenca, J. (Alternate Director)
3/01/22 → 1/02/24
Project: RESEARCH
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FONDECYT REGULAR - 1211376: INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL
Cuenca, J. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Khoury, M. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & Kurte, M. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics for knee osteoarthritis
Figueroa-Valdés, A. I., Luz-Crawford, P., Herrera-Luna, Y., Georges-Calderón, N., García, C., Tobar, H. E., Araya, M. J., Matas, J., Donoso-Meneses, D., de la Fuente, C., Cuenca, J., Parra, E., Lillo, F., Varela, C., Cádiz, M. I., Vernal, R., Ortloff, A., Nardocci, G., Castañeda, V. & Adasme-Vidal, C. & 5 others, , Dec 2025, In: Journal of Nanobiotechnology. 23, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Mitochondrial Antiviral Signaling Protein Activation by Retinoic Acid-Inducible Gene I Agonist Triggers Potent Antiviral Defense in Umbilical Cord Mesenchymal Stromal Cells Without Compromising Mitochondrial Function
Castillo-Galán, S., Grünenwald, F., Hidalgo, Y., Cárdenas, J. C., Cadiz, M. I., Alcayaga-Miranda, F., Khoury, M. & Cuenca, J., 14 May 2025, In: International Journal of Molecular Sciences. 26, 10, 4686.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Unraveling the pathogenesis of viral-induced pulmonary arterial hypertension: Possible new therapeutic avenues with mesenchymal stromal cells and their derivatives.
Castillo-Galán, S., Parra, V. & Cuenca, J., Jan 2025, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1871, 1, 167519.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
A Phase I Dose-Escalation Clinical Trial to Assess the Safety and Efficacy of Umbilical Cord-Derived Mesenchymal Stromal Cells in Knee Osteoarthritis
Matas, J., García, C., Poblete, D., Vernal, R., Ortloff, A., Luque-Campos, N., Hidalgo, Y., Cuenca, J., Infante, C., Cadiz, M. I., Khoury, M., Luz-Crawford, P. & Espinoza, F., Mar 2024, In: Stem cells translational medicine. 13, 3, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
A novel porous hydrogel based on hybrid gelation for injectable and tough scaffold implantation and tissue engineering applications
Hidalgo, C., Méndez-Ruette, M., Zavala, G., Viafara-García, S., Novoa, J., Díaz-Calderón, P., González-Arriagada, W. A., Cuenca, J., Khoury, M. & Acevedo Cox, J. P., 24 May 2023, In: Biomedical Materials (Bristol). 18, 4, 045014.Research output: Contribution to journal › Article › peer-review
4 Scopus citations
Prizes
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Beca Predoctoral "Cátedra Severo Ochoa", Consejo Superior de Investigaciones Científicas-Banco Santander Central Hispano.
Cuenca, J. (Recipient), 1 Mar 2002
Prize: Other distinction
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Beca predoctoral “CNIC-BanCaja”, Centro Nacional de Investigaciones Cardiovasculares (CNIC).
Cuenca, J. (Recipient), 1 Oct 2004
Prize: Other distinction
Activities
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Efecto del trasplante de mitocondrias derivadas de células estromales mesenquimales en células pulmonares con un estado viral activado
Cuenca, J. (Examiner)
2024 → …Activity: Examination
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Transfección a corto plazo de un RNA viral a células madre mesenquimales: Efectos sobre la activación MAVS y la función celular y mitocondrial
Cuenca, J. (Examiner)
2022 → …Activity: Examination
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Chilean Society for Cell Biology – XXXIII Annual Meeting
Cuenca, J. (Participant)
25 Nov 2019 → 29 Nov 2019Activity: Participating in or organizing an event › Participating in a conference, workshop, ...
Courses
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Avances en terapia celular
Luz Crawford, P. A., Cuenca, J., Alcayaga-Miranda, F., Khoury, M. & Acevedo, J. P. 13/08/21 → 17/12/21
Course
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TERAPIA CELULAR Y MEDICINA REGENERATIVA
Luz Crawford, P. A., Alcayaga-Miranda, F., Khoury, M. & Cuenca, J. 14/08/18 → 21/12/18
Course