Projects per year
Personal profile
Personal profile
She studied Biochemistry at the Universidad de Chile, Chile. Then she moved to Madrid, Spain, where she did a PhD in Biochemistry and Molecular Biology, at the Universidad Complutense de Madrid (UCM). Currently she works as a Professor and researcher at the Faculty of Medicine of the Universidad de los Andes, as well as holding a position as a researcher at Cells for Cells and Regenero, the Chilean Regenerative Medicine Consortium.
Additional Research Interests
Dr. Cuenca belongs to the Laboratory of Nano-Regenerative Medicine, located in the Center for Biomedical Research and Innovation (CIIB), investigating the therapeutic effect of mesenchymal/stromal stem cells (MSCs) in the treatment of different inflammatory pathologies such as acute respiratory distress syndrome (ARDS), sepsis or wound healing. Research lines: Cell Therapy; Immunomodulatory effects of Mesenchymal Stem Cells; Autoimmune Diseases; Mechanisms in Autoimmune Diseases; Inflammation/miRNA; Molecular and Cellular Biology; Bioprocessing and Cellular Manufacturing
Education/Academic qualification
PhD, Bioquímica y Biología Molecular, Universidad Complutense de Madrid
… → 2006
University Degree, Bioquímico, Universidad de Chile
Research Lines
- Research Lines
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FONDEF IDEA I+D 2023 - 23I10325: Desarrollo de un producto alogénico basado en un hidrogel bioactivo con nanovesículas extracelulares y su validación como tratamiento endodóntico regenerativo
Cuenca, J. (Principal Investigator), Brizuela Cordero, C. I. (Alternate Director), Khoury, M. (Co-Investigator), Alcayaga-Miranda, F. (Co-Investigator), Canedo Marroquin, G. (Co-Investigator) & González-Arriagada, W. A. (Co-Investigator)
National Agency for Research and Development (ANID)
15/06/23 → 15/06/25
Project: Research
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FONDECYT POSTDOCTORADO - 3230447: TRASPLANTE DE MITOCONDRIAS RESISTENTES A LA HIPOXIA: UNA PROMETEDORA TERAPIA CONTRA LA HIPERTENSIÓN PULMONAR HIPÓXICA
Cuenca, J. (Sponsoring Researcher) & Castillo, S. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo (ANID)
15/04/23 → 14/04/26
Project: Research
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IMPACT: CENTER OF INTERVENTIONAL MEDICINE FOR PRECISION AND ADVANCED CELLULAR THERAPY
Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. (Associate Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/21 → 31/10/26
Project: Research
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INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL
Cuenca, J. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Khoury, M. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & Kurte, M. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1211376: INVESTIGATING THE EFFECT OF MAVS-ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRAL-INDUCED ACUTE LUNG INJURY MODEL.
Cuenca, J. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Khoury, M. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & Kurte, M. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics for knee osteoarthritis
Figueroa-Valdés, A. I., Luz-Crawford, P., Herrera-Luna, Y., Georges-Calderón, N., García, C., Tobar, H. E., Araya, M. J., Matas, J., Donoso-Meneses, D., de la Fuente, C., Cuenca, J., Parra, E., Lillo, F., Varela, C., Cádiz, M. I., Vernal, R., Ortloff, A., Nardocci, G., Castañeda, V. & Adasme-Vidal, C. & 5 others, , Dec 2025, In: Journal of Nanobiotechnology. 23, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Unraveling the pathogenesis of viral-induced pulmonary arterial hypertension: Possible new therapeutic avenues with mesenchymal stromal cells and their derivatives.
Castillo-Galán, S., Parra, V. & Cuenca, J., Jan 2025, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1871, 1, 167519.Research output: Contribution to journal › Review article › peer-review
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A Phase I Dose-Escalation Clinical Trial to Assess the Safety and Efficacy of Umbilical Cord-Derived Mesenchymal Stromal Cells in Knee Osteoarthritis
Matas, J., García, C., Poblete, D., Vernal, R., Ortloff, A., Luque-Campos, N., Hidalgo, Y., Cuenca, J., Infante, C., Cadiz, M. I., Khoury, M., Luz-Crawford, P. & Espinoza, F., Mar 2024, In: Stem cells translational medicine. 13, 3, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
A novel porous hydrogel based on hybrid gelation for injectable and tough scaffold implantation and tissue engineering applications
Hidalgo, C., Méndez-Ruette, M., Zavala, G., Viafara-García, S., Novoa, J., Díaz-Calderón, P., González-Arriagada, W. A., Cuenca, J., Khoury, M. & Acevedo Cox, J. P., 24 May 2023, In: Biomedical Materials (Bristol). 18, 4, 045014.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Safety and efficacy of clinical-grade, cryopreserved menstrual blood mesenchymal stromal cells in experimental acute respiratory distress syndrome
Alcayaga-Miranda, F., Dutra Silva, J., Parada, N., Andrade da Silva, L. H., Ferreira Cruz, F., Utreras, Y., Hidalgo, Y., Cádiz, M. I., Tapia Limonchi, R., Espinoza, F., Bruhn, A., Khoury, M., R. M. Rocco, P. & Cuenca, J., 30 Jan 2023, In: Frontiers in Cell and Developmental Biology. 11, p. 1031331 1031331.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Prizes
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Beca Predoctoral "Cátedra Severo Ochoa", Consejo Superior de Investigaciones Científicas-Banco Santander Central Hispano.
Cuenca, J. (Recipient), 1 Mar 2002
Prize: Other distinction
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Beca predoctoral “CNIC-BanCaja”, Centro Nacional de Investigaciones Cardiovasculares (CNIC).
Cuenca, J. (Recipient), 1 Oct 2004
Prize: Other distinction
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Chilean Society for Cell Biology – XXXIII Annual Meeting
Cuenca, J. (Participant)
25 Nov 2019 → 29 Nov 2019Activity: Participating in or organizing an event › Participating in a conference, workshop, ...
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Stem cells translational medicine (Journal)
Cuenca, J. (Reviewer)
2 Jan 2019 → 1 Oct 2022Activity: Publication peer-review and editorial work › Publication Peer-review
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International Society of Cell and Gene Therapy, ISCT Annual Meeting
Cuenca, J. (Participant)
29 May 2019 → 1 Jun 2019Activity: Participating in or organizing an event › Participating in a conference, workshop, ...
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Cell Therapy Manufacturing & Gene Therapy Congress
Cuenca, J. (Participant)
4 Dec 2018 → 6 Dec 2018Activity: Participating in or organizing an event › Participating in a conference, workshop, ...
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Arthritis and Rheumatology (Journal)
Cuenca, J. (Reviewer)
1 Jan 2017 → 1 Oct 2022Activity: Publication peer-review and editorial work › Publication Peer-review
Courses
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Avances en terapia celular
Luz Crawford, P. A., Cuenca, J., Alcayaga-Miranda, F., Khoury, M. & Acevedo, J. P. 13/08/21 → 17/12/21
Course
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TERAPIA CELULAR Y MEDICINA REGENERATIVA
Luz Crawford, P. A., Alcayaga-Miranda, F., Khoury, M. & Cuenca, J. 14/08/18 → 21/12/18
Course