Projects per year
Personal profile
Professional Information
Dr. Alcayaga-Miranda obtained her veterinary degree from the Universidad Mayor - Chile. She also obtained a PhD from the Universidad Autonoma de Barcelona - Spain. From 2006 to 2010, Dra. Alcayaga-Miranda contributed to the development of oncolytic adenoviruses, a class of targeted anticancer therapy, as part of her PhD thesis. Dra. Alcayaga-Miranda joined to Universidad de los Andes in 2011.
Additional Research Interests
As researcher, she is currently focused on the study of exosomes as therapeutic tool to treat solid tumors and degenerative diseases as osteoarthritis. She is also author of more than 15 original articles, reviews and books chapters in oncology, regenerative medicine and exosomes fields. Currently, Dra. Alcayaga-Miranda is Senior Researcher in Cells for Cells & Consorcio Regenero and Associate Professor in Medicine Faculty of Universidad de los Andes.
Education/Academic qualification
PhD, Veterinaria, Universidad Autónoma de Barcelona
… → 2009
University Degree, Veterinaria, Universidad Mayor
External positions
Integrante de Panel Medicina G1 del Concurso Fondecyt, Agencia Nacional de Investigación y Desarrollo
2023 → …
Evaluadora del Programa de Atracción e Inserción de Capital Humano Avanzado (PAI), Agencia Nacional de Investigación y Desarrollo
2019 → …
Research Lines
- Research Lines
Fingerprint
Dive into the research topics where Francisca Alcayaga-Miranda is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FONDECYT REGULAR - 1230875: REVEALING THE CONTRIBUTION OF MELANOMA-DERIVED CIRCULATING CELL-FREE MITOCHONDRIA IN THE FORMATION OF PREMETASTATIC NICHE IN LYMPH NODES AND THEIR IMPACT IN THE EARLY DEVELOPMENT OF METASTASIS
Alcayaga-Miranda, F. (Principal Investigator), Khoury, M. (Co-Investigator), Pino-Lagos, K. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & González-Arriagada, W. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/23 → 31/03/27
Project: Research
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IMPACT: CENTER OF INTERVENTIONAL MEDICINE FOR PRECISION AND ADVANCED CELLULAR THERAPY
Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. (Associate Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/21 → 31/10/26
Project: Research
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Exosomas como agentes inmunogénicos en el tratamiento de cáncer de mama.
Alcayaga-Miranda, F. (Principal Investigator)
Project: Research
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FONDEF IDEA I+D 2023 - 23I10325: Desarrollo de un producto alogénico basado en un hidrogel bioactivo con nanovesículas extracelulares y su validación como tratamiento endodóntico regenerativo
Cuenca, J. (Principal Investigator), Brizuela Cordero, C. I. (Alternate Director), Khoury, M. (Co-Investigator), Alcayaga-Miranda, F. (Co-Investigator), Canedo Marroquin, G. (Co-Investigator) & González-Arriagada, W. A. (Co-Investigator)
National Agency for Research and Development (ANID)
15/06/23 → 15/06/25
Project: Research
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Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis
Luz Crawford, P. A. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Elizondo-Vega, R. J. (Co-Investigator), Espinoza, F. (Co-Investigator) & Matas, J. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/21 → 30/11/23
Project: Research
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Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics for knee osteoarthritis
Figueroa-Valdés, A. I., Luz-Crawford, P., Herrera-Luna, Y., Georges-Calderón, N., García, C., Tobar, H. E., Araya, M. J., Matas, J., Donoso-Meneses, D., de la Fuente, C., Cuenca, J., Parra, E., Lillo, F., Varela, C., Cádiz, M. I., Vernal, R., Ortloff, A., Nardocci, G., Castañeda, V. & Adasme-Vidal, C. & 5 others, , Dec 2025, In: Journal of Nanobiotechnology. 23, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Gut Microbiota-Derived Extracellular Vesicles Influence Alcohol Intake Preferences in Rats
Díaz-Ubilla, M., Figueroa-Valdés, A. I., Tobar, H. E., Quintanilla, M. E., Díaz, E., Morales, P., Berríos-Cárcamo, P., Santapau, D., Gallardo, J., de Gregorio, C., Ugalde, J., Rojas, C., Gonzalez-Madrid, A., Ezquer, M., Israel, Y., Alcayaga-Miranda, F. & Ezquer, F., Mar 2025, In: Journal of Extracellular Vesicles. 14, 3, e70059.Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial Antiviral Signaling Protein Activation by Retinoic Acid-Inducible Gene I Agonist Triggers Potent Antiviral Defense in Umbilical Cord Mesenchymal Stromal Cells Without Compromising Mitochondrial Function
Castillo-Galán, S., Grünenwald, F., Hidalgo, Y., Cárdenas, J. C., Cadiz, M. I., Alcayaga-Miranda, F., Khoury, M. & Cuenca, J., May 2025, In: International Journal of Molecular Sciences. 26, 10, 4686.Research output: Contribution to journal › Article › peer-review
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Levels of Small Extracellular Vesicles Containing hERG-1 and Hsp47 as Potential Biomarkers for Cardiovascular Diseases
Osorio, L. A., Lozano, M., Soto, P., Moreno-Hidalgo, V., Arévalo-Gil, A., Ramírez-Balaguera, A., Hevia, D., Cifuentes, J., Hidalgo, Y., Alcayaga-Miranda, F., Pasten, C., Morales, D., Varela, D., Urquidi, C., Iturriaga, A., Rivera-Palma, A., Larrea-Gómez, R. & Irarrázabal, C. E., May 2024, In: International Journal of Molecular Sciences. 25, 9, 4913.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
CR5/CCL5 axis is linked to a poor outcome, and inhibition reduces metastasis in oral squamous cell carcinoma
González-Arriagada, W. A., Coletta, R. D., Lozano-Burgos, C., García, C., Maripillán, J., Alcayaga-Miranda, F., Godínez-Pacheco, B., Oyarce-Pezoa, S., Martínez-Flores, R. & García, I. E., 13 Oct 2023, In: Journal of Cancer Research and Clinical Oncology. 149, 19, p. 17335-17346 12 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations
Activities
- 3 Examination
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Evaluadora del Programa Formación de Capital Humano Avanzado (PFCHA) de ANID.
Alcayaga-Miranda, F. (Examiner)
2019 → …Activity: Examination
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Evaluador/a del Programa de Atracción e Inserción de Capital Humano Avanzado (PAI) de ANID.
Alcayaga-Miranda, F. (Examiner)
2019Activity: Examination
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Miembro de comités de revisores externos de revistas científicas
Alcayaga-Miranda, F. (Examiner)
2014 → …Activity: Examination
Courses
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Avances en terapia celular
Luz Crawford, P. A., Cuenca, J., Alcayaga-Miranda, F., Khoury, M. & Acevedo, J. P. 13/08/21 → 17/12/21
Course
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DOCB1210 Avances Biotecnológicos en Medicina
Course
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Introduccion a la Medicina Regenerativa
Luz Crawford, P. A., Khoury, M. & Alcayaga-Miranda, F. 11/03/21 → 16/07/21
Course
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INTRODUCCION A LA MEDICINA REGENERATIVA
Luz Crawford, P. A., Alcayaga-Miranda, F. & Khoury, M. 14/08/20 → 18/12/20
Course
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TERAPIA CELULAR Y MEDICINA REGENERATIVA
Luz Crawford, P. A., Alcayaga-Miranda, F., Khoury, M. & Cuenca, J. 14/08/18 → 21/12/18
Course