Projects per year
Personal profile
Professional Information
Dr. Alcayaga-Miranda obtained her veterinary degree from the Universidad Mayor - Chile. She also obtained a PhD from the Universidad Autonoma de Barcelona - Spain. From 2006 to 2010, Dra. Alcayaga-Miranda contributed to the development of oncolytic adenoviruses, a class of targeted anticancer therapy, as part of her PhD thesis. Dra. Alcayaga-Miranda joined to Universidad de los Andes in 2011. As researcher, she is currently focused on the study of exosomes as therapeutic tool to treat solid tumors and degenerative diseases as osteoarthritis. She is also author of more than 15 original articles, reviews and books chapters in oncology, regenerative medicine and exosomes fields. Currently, Dra. Alcayaga-Miranda is Senior Researcher in Cells for Cells & Consorcio Regenero and Associate Professor in Medicine Faculty of Universidad de los Andes.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Project Number: ID23I10325: Desarrollo de un producto alogénico basado en un hidrogel bioactivo con nanovesículas extracelulares y su validación como tratamiento endodóntico regenerativo
Cuenca, J., Brizuela Cordero, C., Khoury, M., Alcayaga-Miranda, F., Canedo Marroquin, G. & González-Arriagada, W.
National Agency for Research and Development (ANID)
15/06/23 → 15/06/25
Project: Research
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Project Number: 1230875: REVEALING THE CONTRIBUTION OF MELANOMA-DERIVED CIRCULATING CELL-FREE MITOCHONDRIA IN THE FORMATION OF PREMETASTATIC NICHE IN LYMPH NODES AND THEIR IMPACT IN THE EARLY DEVELOPMENT OF METASTASIS
Alcayaga-Miranda, F., Khoury, M., Pino-Lagos, K. & Hidalgo, Y.
National Agency for Research and Development (ANID)
1/04/23 → 31/03/27
Project: Research
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Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis
Luz Crawford, P. A., Alcayaga-Miranda, F., Elizondo-Vega, R. J., Espinoza, F. & Matas, J.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/11/21 → 30/11/23
Project: Research
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Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT)
Khoury, M., Alcayaga-Miranda, F., Cuenca, J., Acevedo, J. P., Figueroa, F., Luz Crawford, P. A., Wyneken, Ú., Illanes, S., Batiz, L. F., Busso, D., J. Monteiro, L., Nardocci, G., Enrione, J. I., Espinoza, F., Valenzuela Bravo, M. T. & Prieto, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/11/21 → 31/10/26
Project: Research
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INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL
Cuenca, J., Alcayaga-Miranda, F., Khoury, M., Hidalgo, Y. & Kurte, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/04/21 → 31/03/25
Project: Research
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Oral Administration as a Potential Alternative for the Delivery of Small Extracellular Vesicles
Donoso-Meneses, D., Figueroa-Valdés, A. I., Khoury, M. & Alcayaga-Miranda, F., 21 Feb 2023, In: Pharmaceutics. 15, 3, p. 716 716.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Safety and efficacy of clinical-grade, cryopreserved menstrual blood mesenchymal stromal cells in experimental acute respiratory distress syndrome
Alcayaga-Miranda, F., Dutra Silva, J., Parada, N., Andrade da Silva, L. H., Ferreira Cruz, F., Utreras, Y., Hidalgo, Y., Cádiz, M. I., Tapia Limonchi, R., Espinoza, F., Bruhn, A., Khoury, M., R. M. Rocco, P. & Cuenca, J., 30 Jan 2023, In: Frontiers in Cell and Developmental Biology. 11, p. 1031331 1031331.Research output: Contribution to journal › Article › peer-review
Open Access -
CD49b Targeting Inhibits Tumor Growth and Boosts Anti-tumor Immunity
Contreras-Kallens, P., Gálvez-Jirón, F., De Solminihac, J., Elhusseiny, A., González-Arriagada, W. A., Alcayaga-Miranda, F., Noelle, R. J. & Pino-Lagos, K., 4 Jul 2022, In: Frontiers in Oncology. 12, p. 928498 928498.Research output: Contribution to journal › Article › peer-review
Open Access -
Turning adversity into opportunity: Small extracellular vesicles as nanocarriers for tumor-associated macrophages re-education
Donoso-Meneses, D., Figueroa-Valdés, A. I., Georges, N., Tobar, H. E. & Alcayaga-Miranda, F., 2022, (Accepted/In press) In: Bioengineering and Translational Medicine.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells
Figueroa-Valdés, A. I., de la Fuente, C., Hidalgo, Y., Vega-Letter, A. M., Tapia-Limonchi, R., Khoury, M. & Alcayaga Miranda, F., 26 May 2021, In: Frontiers in Bioengineering and Biotechnology. 9, p. 619930 619930.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations
Activities
- 3 Examination
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Evaluador/a del Programa de Atracción e Inserción de Capital Humano Avanzado (PAI) de ANID.
Francisca Alcayaga-Miranda (Examiner)
2019Activity: Examination
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Evaluadora del Programa Formación de Capital Humano Avanzado (PFCHA) de ANID.
Francisca Alcayaga-Miranda (Examiner)
2019 → …Activity: Examination
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Miembro de comités de revisores externos de revistas científicas
Francisca Alcayaga-Miranda (Examiner)
2014 → …Activity: Examination
Courses
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Avances en terapia celular
Patricia Alejandra Luz Crawford, Jimena Cuenca, Francisca Alcayaga-Miranda, Maroun Khoury & Juan Pablo Acevedo 13/08/21 → 17/12/21
Course
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DOCB1210 Avances Biotecnológicos en Medicina
Course
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Introduccion a la Medicina Regenerativa
Patricia Alejandra Luz Crawford, Maroun Khoury & Francisca Alcayaga-Miranda 11/03/21 → 16/07/21
Course
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INTRODUCCION A LA MEDICINA REGENERATIVA
Patricia Alejandra Luz Crawford, Francisca Alcayaga-Miranda & Maroun Khoury 14/08/20 → 18/12/20
Course
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TERAPIA CELULAR Y MEDICINA REGENERATIVA
Patricia Alejandra Luz Crawford, Francisca Alcayaga-Miranda, Maroun Khoury & Jimena Cuenca 14/08/18 → 21/12/18
Course
Press/Media
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Findings from University of los Andes Advance Knowledge in Acute Respiratory Distress Syndrome (Safety and efficacy of clinical-grade, cryopreserved menstrual blood mesenchymal stromal cells in experimental acute respiratory distress syndrome)
Francisca Alcayaga-Miranda, Maroun Khoury & Francisco Espinoza
10/02/23
1 item of Media coverage
Press/Media