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Personal profile
Professional Information
Dr. Alcayaga-Miranda obtained her veterinary degree from the Universidad Mayor - Chile. She also obtained a PhD from the Universidad Autonoma de Barcelona - Spain. From 2006 to 2010, Dra. Alcayaga-Miranda contributed to the development of oncolytic adenoviruses, a class of targeted anticancer therapy, as part of her PhD thesis. Dra. Alcayaga-Miranda joined to Universidad de los Andes in 2011. As researcher, she is currently focused on the study of exosomes as therapeutic tool to treat solid tumors and degenerative diseases as osteoarthritis. She is also author of more than 15 original articles, reviews and books chapters in oncology, regenerative medicine and exosomes fields. Currently, Dra. Alcayaga-Miranda is Senior Researcher in Cells for Cells & Consorcio Regenero and Associate Professor in Medicine Faculty of Universidad de los Andes.
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Projects
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Exospand: suplemento humano para expansión de células progenitoras hematopoyéticas
1/06/15 → 28/11/15
Project: Research
Research output
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Exosomes on the border of species and kingdom intercommunication
Schuh, C. M. A. P., Cuenca, J., Alcayaga-Miranda, F. & Khoury, M., 1 Aug 2019, In: Translational Research. 210, p. 80-98 19 p.Research output: Contribution to journal › Scientific review › peer-review
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Stem cell exosomes inhibit angiogenesis and tumor growth of oral squamous cell carcinoma
Rosenberger, L., Ezquer, M., Lillo-Vera, F., Pedraza, P. L., Ortúzar, M. I., González, P. L., Figueroa-Valdés, A. I., Cuenca, J., Ezquer, F., Khoury, M. & Alcayaga-Miranda, F., 1 Dec 2019, In: Scientific Reports. 9, 1Research output: Contribution to journal › Article › peer-review
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Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial
Matas, J., Orrego, M., Amenabar, D., Infante, C., Tapia-Limonchi, R., Cadiz, M. I., Alcayaga-Miranda, F., González, P. L., Muse, E., Khoury, M., Figueroa, F. E. & Espinoza, F., 1 Mar 2019, In: Stem cells translational medicine. 8, 3, p. 215-224 10 p.Research output: Contribution to journal › Article › peer-review
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The reparative abilities of menstrual stem cells modulate the wound matrix signals and improve cutaneous regeneration
Cuenca, J., Le-Gatt, A., Castillo, V., Belletti, J., Díaz, M., Kurte, G. M., Gonzalez, P. L., Alcayaga-Miranda, F., Schuh, C. M. A. P., Ezquer, F., Ezquer, M. & Khoury, M., 14 May 2018, In: Frontiers in Physiology. 9, MAYResearch output: Contribution to journal › Article › peer-review
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ANTI-ANGIOGENIC THERAPY BASED ON EXOSOMES DERIVED FROM MENSTRUAL STEM CELLS
Khoury, M. & Alcayaga, F., 20 Apr 2017, IPC No. C12N 5/ 078 A I, Patent No. WO2017064647, Priority date 13 Oct 2015, Priority No. US201562240756PResearch output: Patent