Projects per year
Personal profile
Professional Information
Dr. Alcayaga-Miranda obtained her veterinary degree from the Universidad Mayor - Chile. She also obtained a PhD from the Universidad Autonoma de Barcelona - Spain. From 2006 to 2010, Dra. Alcayaga-Miranda contributed to the development of oncolytic adenoviruses, a class of targeted anticancer therapy, as part of her PhD thesis. Dra. Alcayaga-Miranda joined to Universidad de los Andes in 2011. As researcher, she is currently focused on the study of exosomes as therapeutic tool to treat solid tumors and degenerative diseases as osteoarthritis. She is also author of more than 15 original articles, reviews and books chapters in oncology, regenerative medicine and exosomes fields. Currently, Dra. Alcayaga-Miranda is Senior Researcher in Cells for Cells & Consorcio Regenero and Associate Professor in Medicine Faculty of Universidad de los Andes.
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Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis
Luz Crawford, P. A., Alcayaga-Miranda, F., Elizondo-Vega, R. J., Espinoza, F. & Matas, J.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/11/21 → 30/11/23
Project: Research
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Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT)
Khoury, M., Alcayaga-Miranda, F., Cuenca, J., Acevedo, J. P., Figueroa, F., Luz Crawford, P. A., Wyneken, Ú., Illanes, S., Batiz, L. F., Busso, D., Busso, D., J. Monteiro, L., Nardocci, G., Enrione, J., Espinoza, F., Valenzuela Bravo, M. T. & Prieto, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/11/21 → 31/10/26
Project: Research
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INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL
Cuenca, J., Alcayaga-Miranda, F., Khoury, M., Hidalgo, Y. & Kurte, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/04/21 → 31/03/25
Project: Research
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A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells
Figueroa-Valdés, A. I., de la Fuente, C., Hidalgo, Y., Vega-Letter, A. M., Tapia-Limonchi, R., Khoury, M. & Alcayaga Miranda, F., 26 May 2021, In: Frontiers in Bioengineering and Biotechnology. 9, p. 619930 619930.Research output: Contribution to journal › Article › peer-review
Open Access -
Camouflage strategies for therapeutic exosomes evasion from phagocytosis
Parada, N., Romero-Trujillo, A., Georges, N. & Alcayaga Miranda, F., 1 Jul 2021, In: Journal of Advanced Research. 31, p. 61-74 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Exosomes on the border of species and kingdom intercommunication
Schuh, C. M. A. P., Cuenca, J., Alcayaga-Miranda, F. & Khoury, M., Aug 2019, In: Translational Research. 210, p. 80-98 19 p.Research output: Contribution to journal › Review article › peer-review
12 Scopus citations -
Stem cell exosomes inhibit angiogenesis and tumor growth of oral squamous cell carcinoma
Rosenberger, L., Ezquer, M., Lillo-Vera, F., Pedraza, P. L., Ortúzar, M. I., González, P. L., Figueroa-Valdés, A. I., Cuenca, J., Ezquer, F., Khoury, M. & Alcayaga-Miranda, F., 1 Dec 2019, In: Scientific Reports. 9, 1, 663.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial
Matas, J., Orrego, M., Amenabar, D., Infante, C., Tapia-Limonchi, R., Cadiz, M. I., Alcayaga-Miranda, F., González, P. L., Muse, E., Khoury, M., Figueroa, F. E. & Espinoza, F., Mar 2019, In: Stem cells translational medicine. 8, 3, p. 215-224 10 p.Research output: Contribution to journal › Article › peer-review
Open Access86 Scopus citations
Activities
- 3 Examination
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Evaluador/a del Programa de Atracción e Inserción de Capital Humano Avanzado (PAI) de ANID.
Francisca Alcayaga-Miranda (Examiner)
2019Activity: Examination
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Evaluadora del Programa Formación de Capital Humano Avanzado (PFCHA) de ANID.
Francisca Alcayaga-Miranda (Examiner)
2019 → …Activity: Examination
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Miembro de comités de revisores externos de revistas científicas
Francisca Alcayaga-Miranda (Examiner)
2014 → …Activity: Examination
Courses
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Avances en terapia celular
Patricia Alejandra Luz Crawford, Jimena Cuenca, Francisca Alcayaga-Miranda, Maroun Khoury & Juan Pablo Acevedo 13/08/21 → 17/12/21
Course
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DOCB1210 Avances Biotecnológicos en Medicina
Course
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Introduccion a la Medicina Regenerativa
Patricia Alejandra Luz Crawford, Maroun Khoury & Francisca Alcayaga-Miranda 11/03/21 → 16/07/21
Course
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INTRODUCCION A LA MEDICINA REGENERATIVA
Patricia Alejandra Luz Crawford, Francisca Alcayaga-Miranda & Maroun Khoury 14/08/20 → 18/12/20
Course
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TERAPIA CELULAR Y MEDICINA REGENERATIVA
Patricia Alejandra Luz Crawford, Francisca Alcayaga-Miranda, Maroun Khoury & Jimena Cuenca 14/08/18 → 21/12/18
Course