Projects per year
Personal profile
Professional Information
Dr. Alcayaga-Miranda obtained her veterinary degree from the Universidad Mayor - Chile. She also obtained a PhD from the Universidad Autonoma de Barcelona - Spain. From 2006 to 2010, Dra. Alcayaga-Miranda contributed to the development of oncolytic adenoviruses, a class of targeted anticancer therapy, as part of her PhD thesis. Dra. Alcayaga-Miranda joined to Universidad de los Andes in 2011. As researcher, she is currently focused on the study of exosomes as therapeutic tool to treat solid tumors and degenerative diseases as osteoarthritis. She is also author of more than 15 original articles, reviews and books chapters in oncology, regenerative medicine and exosomes fields. Currently, Dra. Alcayaga-Miranda is Senior Researcher in Cells for Cells & Consorcio Regenero and Associate Professor in Medicine Faculty of Universidad de los Andes.
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Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT)
Khoury, M., Alcayaga-Miranda, F., Cuenca, J., Acevedo, J. P., Figueroa, F., Luz Crawford, P. A., Wyneken, Ú., Illanes, S., Batiz, L. F., Busso, D., J. Monteiro, L., Nardocci, G., Enrione, J. I., Espinoza, F., Valenzuela Bravo, M. T. & Prieto, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/11/21 → 31/10/26
Project: Research
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Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis
Luz Crawford, P. A., Alcayaga-Miranda, F., Elizondo-Vega, R. J., Espinoza, F. & Matas, J.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/11/21 → 30/11/23
Project: Research
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INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL
Cuenca, J., Alcayaga-Miranda, F., Khoury, M., Hidalgo, Y. & Kurte, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/04/21 → 31/03/25
Project: Research
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Safety and efficacy of clinical-grade, cryopreserved menstrual blood mesenchymal stromal cells in experimental acute respiratory distress syndrome
Alcayaga-Miranda, F., Dutra Silva, J., Parada, N., Andrade da Silva, L. H., Ferreira Cruz, F., Utreras, Y., Hidalgo, Y., Cádiz, M. I., Tapia Limonchi, R., Espinoza, F., Bruhn, A., Khoury, M., R. M. Rocco, P. & Cuenca, J., 30 Jan 2023, In: Frontiers in Cell and Developmental Biology. 11, 1031331.Research output: Contribution to journal › Article › peer-review
Open Access -
CD49b Targeting Inhibits Tumor Growth and Boosts Anti-tumor Immunity
Contreras-Kallens, P., Gálvez-Jirón, F., De Solminihac, J., Elhusseiny, A., González-Arriagada, W. A., Alcayaga-Miranda, F., Noelle, R. J. & Pino-Lagos, K., 4 Jul 2022, In: Frontiers in Oncology. 12, p. 928498 928498.Research output: Contribution to journal › Article › peer-review
Open Access -
Turning adversity into opportunity: Small extracellular vesicles as nanocarriers for tumor-associated macrophages re-education
Donoso-Meneses, D., Figueroa-Valdés, A. I., Georges, N., Tobar, H. E. & Alcayaga-Miranda, F., 2022, (Accepted/In press) In: Bioengineering and Translational Medicine.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells
Figueroa-Valdés, A. I., de la Fuente, C., Hidalgo, Y., Vega-Letter, A. M., Tapia-Limonchi, R., Khoury, M. & Alcayaga Miranda, F., 26 May 2021, In: Frontiers in Bioengineering and Biotechnology. 9, p. 619930 619930.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Camouflage strategies for therapeutic exosomes evasion from phagocytosis
Parada, N., Romero-Trujillo, A., Georges, N. & Alcayaga Miranda, F., 1 Jul 2021, In: Journal of Advanced Research. 31, p. 61-74 14 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations
Activities
- 3 Examination
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Evaluadora del Programa Formación de Capital Humano Avanzado (PFCHA) de ANID.
Francisca Alcayaga-Miranda (Examiner)
2019 → …Activity: Examination
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Evaluador/a del Programa de Atracción e Inserción de Capital Humano Avanzado (PAI) de ANID.
Francisca Alcayaga-Miranda (Examiner)
2019Activity: Examination
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Miembro de comités de revisores externos de revistas científicas
Francisca Alcayaga-Miranda (Examiner)
2014 → …Activity: Examination
Courses
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Avances en terapia celular
Patricia Alejandra Luz Crawford, Jimena Cuenca, Francisca Alcayaga-Miranda, Maroun Khoury & Juan Pablo Acevedo 13/08/21 → 17/12/21
Course
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DOCB1210 Avances Biotecnológicos en Medicina
Course
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Introduccion a la Medicina Regenerativa
Patricia Alejandra Luz Crawford, Maroun Khoury & Francisca Alcayaga-Miranda 11/03/21 → 16/07/21
Course
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INTRODUCCION A LA MEDICINA REGENERATIVA
Patricia Alejandra Luz Crawford, Francisca Alcayaga-Miranda & Maroun Khoury 14/08/20 → 18/12/20
Course
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TERAPIA CELULAR Y MEDICINA REGENERATIVA
Patricia Alejandra Luz Crawford, Maroun Khoury & Francisca Alcayaga-Miranda 16/08/19 → 20/12/19
Course
Press/Media
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Findings from University of los Andes Advance Knowledge in Acute Respiratory Distress Syndrome (Safety and efficacy of clinical-grade, cryopreserved menstrual blood mesenchymal stromal cells in experimental acute respiratory distress syndrome)
Francisca Alcayaga-Miranda & Maroun Khoury
10/02/23
1 item of Media coverage
Press/Media