Projects per year
Personal profile
Professional Information
He studied Veterinary Medicine at the Catholic University of Temuco, Chile. He obtained his PhD in Medical Sciences from the Austral University of Chile. He completed his postdoctoral research at the University of the Andes. He is currently a faculty member and researcher at the Faculty of Medicine, University of the Andes.
Research interests
His research group is currently focused on two main lines of investigation. The first explores the cellular and molecular mechanisms that regulate neurogenesis, examining the role of genetic and environmental factors in the development and maturation of the central nervous system. The second line characterizes the biological processes involved in the onset and persistence of pain in osteoarticular pathologies, with emphasis on the interaction between sensory neurons and chondrocytes, as well as the analysis of signaling pathways implicated in pain chronification.
Teaching
Coordinator and Professor of the Minor in Physical Activity, Sport and Health at the School of Kinesiology, University of the Andes. Guest faculty in the Doctoral Program in Biomedical Sciences, University of the Andes. His main teaching areas are Well-being Neuroscience, Energy Metabolism, Nervous System Formation, and Pain Pathways.
Education/Academic qualification
PhD, Medical Sciences, Universidad Austral de Chile
2015 → 2019
University Degree, Doctor of Veterinary Medicine, Universidad Católica de Temuco
2009 → 2014
Keywords
- R Medicine (General)
Open Keywords
- Neuroscience
- Energy Metabolism
- Mitochondria
- Pain
Research Lines
- Research Lines
- Neurobiology of Pain
- Biology of Neural Stem Cells and Brain Development
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Collaborations and top research areas from the last five years
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FONDECYT INICIACIÓN - 11251364: CHONDROCYTE-DERIVED NETRIN-1 AS A DRIVING MECHANISM OF SENSORY INNERVATION IN OSTEOARTHRITIS: FOCUS ON SUBCHONDRAL BONE REMODELING AND DORSAL ROOT GANGLION SENSITIZATION
Bustamante Barrientos, F. A. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/25 → 31/03/28
Project: RESEARCH
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FONDECYT POSTDOCTORADO - 3220204: TRANSFERENCIA MITOCONDRIAL DESDE CÉLULAS MADRE MESENQUIMALES COMO UNA NUEVA ALTERNATIVA TERAPÉUTICA PARA DESÓRDENES DEL NEURODESARROLLO: RELEVANCIA EN EL RESCATE METABÓLICO Y FUNCIONAL DE CÉLULAS MADRE NEURALES
Luz Crawford, P. A. (Sponsoring Researcher) & Bustamante Barrientos, F. A. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo
15/04/22 → 14/04/25
Project: RESEARCH
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Mitochondria-derived reactive oxygen species induce over-differentiation of neural stem/progenitor cells after non-cytotoxic cisplatin exposure
Bustamante-Barrientos, F. A., Lara-Barba, E., Herrera-Luna, Y., García-Guerrero, C., Silva-Pavez, E., Morales-Reyes, J., Araya, M. J., Yanten-Fuentes, L., Luque-Campos, N., Altamirano, C., Vega-Letter, A. M. & Luz-Crawford, P., 2025, In: Frontiers in Cell and Developmental Biology. 13, 1555153.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
New mesenchymal stem/stromal cell-based strategies for osteoarthritis treatment: targeting macrophage-mediated inflammation to restore joint homeostasis
Araya-Sapag, M. J., Lara-Barba, E., García-Guerrero, C., Herrera-Luna, Y., Flores-Elías, Y., Bustamante-Barrientos, F. A., Albornoz, G. G., Contreras-Fuentes, C., Yantén-Fuentes, L., Luque-Campos, N., Vega-Letter, A. M., Toledo, J. & Luz-Crawford, P., Jun 2025, In: Journal of Molecular Medicine. 103, 6, p. 651-669 19 p.Research output: Contribution to journal › Review article › peer-review
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Safety and efficacy of mesenchymal stromal cells mitochondria transplantation as a cell-free therapy for osteoarthritis
Vega-Letter, A. M., García-Guerrero, C., Yantén-Fuentes, L., Pradenas, C., Herrera-Luna, Y., Lara-Barba, E., Bustamante-Barrientos, F. A., Rojas, M., Araya, M. J., Jeraldo, N., Aros, C., Troncoso, F., Poblete, D., Court, A., Ortloff, A., Barraza, J., Velarde, F., Farkas, C., Carril, C. & Luque-Campos, N. & 16 others, , Dec 2025, In: Journal of Translational Medicine. 23, 1, 26.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK
Bustamante-Barrientos, F. A., Méndez-Ruette, M., Molina, L., Koning, T., Ehrenfeld, P., González, C. B., Wyneken, U., Henzi, R. & Bátiz, L. F., 2023, In: Frontiers in Cell and Developmental Biology. 11, p. 1061777 1061777.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Exploring the therapeutic potential of the mitochondrial transfer-associated enzymatic machinery in brain degeneration
Luque-Campos, N., Riquelme, R., Molina, L., Canedo-Marroquín, G., Vega-Letter, A. M., Luz-Crawford, P. & Bustamante-Barrientos, F. A., 27 Jul 2023, In: Frontiers in Physiology. 14, p. 1-14 14 p., 1217815.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations