Projects per year
Personal profile
Research Interests
I am an associate professor in the ordinary career of the dental faculty of the Universidad de Los Andes, Santiago, Chile. The areas of interest in research profiles are, bioengineering associated with regenerative therapy of human dental pulp. I am working with dental stem cells since 2010 in the field of regenerative endodontics. Our team was the first to conduct a controlled clinical trial using allogeneic stem cells (2020) to regenerate human dental pulp. This research was titled "Development of an Innovative Therapeutic Strategy Based on the Use of a New Cellular Product for the Regeneration of Human Dental Pulp." This study was published in 2020 in the prestigious journal " Journal of Dental Research". We also develop a product based on alogeneic stem cells that are in the process of being patented. The second line of research that we are developing is just starting is" Biomarkers for diagnosis in endodontics". My work team has awarded competitive funds such as FONIS, CORFO L1, and CORFO L2. In terms of publications, I have published articles in prestigious journal from 2014 to date.
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- 2 Similar Profiles
Network
Projects
- 3 Finished
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Terapia regenerativa de pulpa dentaria con Células Madre Mesenquimales en pacientes adultos
16/04/14 → 12/10/14
Project: Research
Research output
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Cell-Based Regenerative Endodontics for Treatment of Periapical Lesions: A Randomized, Controlled Phase I/II Clinical Trial
Brizuela, C., Meza, G., Urrejola, D., Quezada, M. A., Concha, G., Ramírez, V., Angelopoulos, I., Cadiz, M. I., Tapia-Limonchi, R. & Khoury, M., 1 May 2020, In: Journal of Dental Research. 99, 5, p. 523-529 7 p.Research output: Contribution to journal › Article › peer-review
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Inflammatory biomarkers in dentinal fluid as an approach to molecular diagnostics in pulpitis
Brizuela, C., Meza, G., Mercadé, M., Inostroza, C., Chaparro, A., Bravo, I., Briceño, C., Hernández, M., Giner, L. & Ramírez, V., 1 Sep 2020, In: International Endodontic Journal. 53, 9, p. 1181-1191 11 p.Research output: Contribution to journal › Article › peer-review
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Mesenchymal Stem Cells Derived from Human Inflamed Dental Pulp Exhibit Impaired Immunomodulatory Capacity In Vitro
Inostroza, C., Vega-Letter, A. M., Brizuela, C., Castrillón, L., Saint Jean, N., Duran, C. M. & Carrión, F., Aug 2020, In: Journal of Endodontics. 46, 8, p. 1091-1098.e2Research output: Contribution to journal › Article › peer-review
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Personalized Cell Therapy for Pulpitis Using Autologous Dental Pulp Stem Cells and Leukocyte Platelet-rich Fibrin: A Case Report
Meza, G., Urrejola, D., Saint Jean, N., Inostroza, C., López, V., Khoury, M. & Brizuela, C., Feb 2019, In: Journal of Endodontics. 45, 2, p. 144-149 6 p.Research output: Contribution to journal › Article › peer-review
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COMPOSITION COMPRISING A SUBSTANTIALLY PURE POPULATION OF MULTIPOTENT STROMAL CELLS ENCAPSULATED IN PLATELET-POOR PLASMA (PPP)
Khoury, M., Brizuela, C. & Angelopoulos, I., 19 Jul 2018, IPC No. A61P 1/ 02 A I, Patent No. WO2018131003, Priority date 16 Jan 2017, Priority No. EP20170151688Research output: Patent
Press / Media
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Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.; RanoKure
2/10/18
1 item of Media coverage
Press/Media
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Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
2/10/18
1 item of Media coverage
Press/Media