Personal profile
Professional Information
Dentist (DDS) and Ph.D. in Dental Sciences from the University of Chile. During her doctoral training, she completed a six-month international research stay under the supervision of Dr. Lesley Smyth at the University of East London (London, United Kingdom).
In 2019 and 2021, she was awarded the Hatton Chile Award by the International Association for Dental Research (IADR), Chile Division. In 2022, she received the IADR Hatton Award in the Senior Basic Research category at the international level (Chengdu, China). That same year, she was also awarded the Hermann Niemeyer Medal by the Chilean Society of Biochemistry and Molecular Biology (SBBMCh), among other distinctions.
Throughout her scientific career, she has disseminated her research findings at both national and international levels. Notable participations include the annual meetings of IADR Chile and the Chilean Association of Immunology (Asochin); IADR meetings in London, Washington, Bogotá, and New Orleans; LAMIG (Latin American Mucosal Immunology Group) in Mexico City; ALACI (Latin American and Caribbean Association of Immunology) in Varadero and Buenos Aires; the IUIS (International Union of Immunological Societies) in Cape Town, South Africa; and the Oral Mucosal Immunology and Microbiome meeting in Crete, Greece.
She is an active member of the IADR Chile Division, the Chilean Association of Immunology (Asochin), and the Society for Mucosal Immunology (SMI). In addition, she has participated in multiple science outreach activities aimed at the general public, including the EXPLORA ANID program, the Art+Science project, and school science fairs, among others.
Currently, she serves as a research faculty member at the Faculty of Dentistry of Universidad de los Andes, supported by a “Strengthening Excellence in Research” initiative. She is also the principal investigator of a Fondecyt Postdoctoral Project, co-investigator on a Fondecyt Regular Project, and collaborator on other ANID-funded research and innovation projects.
Teaching
Professor at the Universidad de Los Andes (UA) in the areas of Cariology and Biomedical Sciences (2024).
Invited professor to the courses of Oral and Maxillofacial Osteoimmunology in the Doctoral Program in Dental Sciences, Faculty of Dentistry, University of Chile (DP-FOUCH, 2022); Applied Molecular Technologies for Diagnosis, Department of Medical Technology, Faculty of Medicine UCH (2023); Immunology and Advanced Microbiology of the Stomatognathic System DP-FOUCH (2022); Fundamentals in Immunology and Advanced Immunology, Doctoral Program in Biomedical Sciences, Faculty of Medicine, UA and Interdisciplinary Seminar, Doctoral Program in Dental Sciences, UA (2024).
Research interests
My research interests are encompassed in the fields of Biomedicine, Translational Medicine and related areas. Particularly, in general, oral and maxillofacial Immunology, Mucosal Immunology, responses associated with microorganism-host interactions, Mechanisms for Immunotherapies, host and bacterial-derived extracellular vesicles, Immunomodulatory strategies and, more recently, Neuroimmunology.
Additionally, although I have not worked directly in these areas, I have a deep interest in Cariology and Public Health.
Education/Academic qualification
PhD, Doctor of Dental Sciences, Universidad de Chile
… → 29 Mar 2023
University Degree, Dental Surgeon, Universidad de Chile
… → 13 Apr 2018
Keywords
- Q Science (General)
Open Keywords
- Immunology
- Periodontitis
- Extracellular Vesicles
- Neuroinflammation
Research Lines
- Research Lines
- Mucosal Immunology
- Host-microbe interactions
- Immune Regulation
- Neuroimmunology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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FAI INSCRIPCIÓN CONGRESOS - APO-CG-2023-28: INCREASED GINGIVAL CREVICULAR FLUID EXTRACELLULAR VESICLES ARE INVOLVED IN THE CROSSTALK BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES
Mizgier, M. L. (Principal Investigator), Realini, O. (Co-Investigator), Bendek Viera, M. J. (Co-Investigator), Rojas Pérez, C. I. (Co-Investigator), Monje, S. (Co-Investigator), Figari, A. (Co-Investigator), Hernández, M. (Co-Investigator), Ramírez Lobos, V. (Co-Investigator), Illanes, S. (Co-Investigator), Busso, D. (Co-Investigator) & Chaparro, A. (Co-Investigator)
Universidad de los Andes Chile
4/09/23 → 30/12/23
Project: RESEARCH
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Induced Treg-Derived Extracellular Vesicles Suppress CD4+ T-Cell-Mediated Inflammation and Ameliorate Bone Loss During Periodontitis Partly Through CD73/Adenosine-Dependent Immunomodulatory Mechanisms
Rojas, C., García, M., González-Osuna, L., Campos-Mora, M., de León, E. P., Sierra-Cristancho, A., Terraza, C., Cortez, C., Sansores-España, L. D., Carvajal, P., Bazoer, J., Peng, Q., Lawson, C., Smyth, L. A., Pino-Lagos, K. & Vernal, R., Jul 2025, In: Journal of Extracellular Vesicles. 14, 7, p. e70118 e70118.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
A novel brain-to-gut communication pathway mediated by astrocyte-derived small extracellular vesicles modulates stress-induced intestinal inflammation
Yantén-Fuentes, L., Pizarro, M., Rojas, C., Pradenas, C., Méndez-Ruette, M., Corvalán, K., Bustos-Quevedo, G., Luarte, A., Batiz, L. F., Luz-Crawford, P., Pino-Lagos, K. & Wyneken, U., Dec 2025, In: Molecular Psychiatry. 30, 12, p. 5710-5721 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
p38 mitogen-activated protein kinase drives senescence in CD4+ T lymphocytes and increases their pathological potential
González-Osuna, L., Fukada, S. Y., Hernández-Cáceres, M. P., Luz-Crawford, P., Cortez, C., Rojas, C., Carvajal, P., Sierra-Cristancho, A. & Vernal, R., Dec 2025, In: Immunity and Ageing. 22, 1, p. 30 30.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Gut Microbiota-Derived Extracellular Vesicles Influence Alcohol Intake Preferences in Rats
Díaz-Ubilla, M., Figueroa-Valdés, A. I., Tobar, H. E., Quintanilla, M. E., Díaz, E., Morales, P., Berríos-Cárcamo, P., Santapau, D., Gallardo, J., de Gregorio, C., Ugalde, J., Rojas, C., Gonzalez-Madrid, A., Ezquer, M., Israel, Y., Alcayaga-Miranda, F. & Ezquer, F., Mar 2025, In: Journal of Extracellular Vesicles. 14, 3, p. e70059 e70059.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation
Campos-Mora, M., De Solminihac, J., Rojas, C., Padilla, C., Kurte, M., Pacheco, R., Kaehne, T., Wyneken, Ú. & Pino-Lagos, K., Jun 2022, In: Journal of Extracellular Vesicles. 11, 6, e12237.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations