Projects per year
Personal profile
Research Interests
Previously to be an independent investigator Dr. Irarrázabal participate in several investigations in the Universidad de Chile. One of his most interesting research was to clarify the mechanisms involved in the specificity of the amino acid transporter y+L system in the human erythrocyte. Besides, he participates in an initiative from the Organization of American States to disseminate the biotechnology interaction between academics and industry. He was co-editor of two books in this area. During his doctoral thesis, he was awarded with two government support grants. The doctoral thesis help to identifies a p53 gene polymorphisms in humans associated with lung cancer susceptibility. After finished the Ph.D. program in the Universidad de Chile, he moved to Bethesda City in the U.S.A. to carry out his postdoc training in renal physiology in the National Institutes of Health (NIH-USA) under the supervision of Dr. Maurice Burg. In NIH, his contribution provided important evidence to understand how the cells survived in hypertonic condition in kidney, helping to clarify the knowledge of the renal function and the osmotic stress response signaling pathway. Right now, he is a full professor and Chief of the Laboratory of Integrative and Molecular Physiology in the Universidad de los Andes (UANDES) in Chile. He has over 30 publications that have been cited over 500 times, and his publication H-index is 18 and has been serving as an editorial board member of reputed Journals. In the UANDES, he has worked in more than 10 research projects generating two patents for clinical application in hypoxia and renal damage.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Fellow Post-Doc, The National Institutes of Health
25 Jun 2002 → 25 Jun 2007
Fingerprint
Dive into the research topics where Carlos Ernesto Irarrazabal Muñoz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 7 Finished
-
1400W Prevents Renal Injury in the Renal Cortex But Not in the Medulla in a Murine Model of Ischemia and Reperfusion Injury
Pasten, C., Lozano, M., Méndez, G. P. & Irarrázabal, C. E., 19 Oct 2022, In: Cellular Physiology and Biochemistry. 56, 5, p. 573-586 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Exploring the Expression of Pro-Inflammatory and Hypoxia-Related MicroRNA-20a, MicroRNA-30e, and MicroRNA-93 in Periodontitis and Gingival Mesenchymal Stem Cells under Hypoxia
Chaparro, A., Lozano, M., Gaedechens, D., López, C., Albers, D., Hernández, M., Pascual, A., Nart, J. & Irarrazabal, C. E., 7 Sep 2022, In: International Journal of Molecular Sciences. 23, 18, 10310.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The Ischemia and Reperfusion Injury Involves the Toll-Like Receptor-4 Participation Mainly in the Kidney Cortex
Herrera-Luna, Y., Lozano, M., Pasten, C., Multhoff, G. & Irarrázabal, C. E., 16 Nov 2022, In: Cellular Physiology and Biochemistry. 56, 6, p. 613-628 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Urinary Extracellular Vesicles as a Source of NGAL for Diabetic Kidney Disease Evaluation in Children and Adolescents With Type 1 Diabetes Mellitus
Ugarte, F., Santapau, D., Gallardo, V., Garfias, C., Yizmeyián, A., Villanueva, S., Sepúlveda, C., Rocco, J., Pasten, C., Urquidi, C., Cavada, G., San Martin, P., Cano, F. & Irarrázabal, C. E., 3 Jan 2022, In: Frontiers in Endocrinology. 12, 654269.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Aminoguanidine prevents the oxidative stress, inhibiting elements of inflammation, endothelial activation, mesenchymal markers, and confers a renoprotective effect in renal ischemia and reperfusion injury
Pasten, C., Lozano, M., Rocco, J., Carrión, F., Alvarado, C., Liberona, J., Michea, L. & Irarrázabal, C. E., Nov 2021, In: Antioxidants. 10, 11, 1724.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations
Courses
-
DOCB1210 Avances Biotecnológicos en Medicina
Course