Personal profile
Professional Information
I studied Biochemistry and developed an early interest in the functioning of the central nervous system. I began my research career by focusing on intercellular communication mediated by brain-derived extracellular vesicles. I also became deeply fascinated by axonal biology and how neurons adapt their cellular machinery to support outgrowth and maintenance.
More recently, I have combined both passions to investigate how extracellular vesicles may hijack axonal protein synthesis to regulate axonal function. Throughout these years, my research activity has been closely interwoven with teaching and organizing courses for both undergraduate and postgraduate students.
Research interests
My research interests focus on understanding the basic cellular biology mechanisms underlying extracellular vesicle-mediated signaling and axonal protein synthesis. I am also involved in exploring how extracellular vesicles contribute to stress-induced adaptations and their potential as diagnostic tools for cognitive and mood disorders. More recently, I have developed a broader interest in the use of cellular automata to study fundamental aspects of neural network functioning.
Teaching
My academic work is primarily focused on teaching neuroscience to medical students and basic cell biology to postgraduate students. I also deliver lectures on image processing and microscopy at the postgraduate level
Education/Academic qualification
Sciences, with a specialization in Cellular and Molecular Biology and Neurosciences, Universidad de Chile
2011 → 2016
University Degree, Biochemist, Universidad de Chile
2004 → 2011
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Collaborations and top research areas from the last five years
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FONDECYT REGULAR - 1251409: UPREGULATION OF FOXO3 ACTIVITY IN INTERNEURON PROGENITOR CELLS AS A PATHOGENIC MECHANISM LINKING PRENATAL STRESS AND NEURODEVELOPMENTAL DISORDERS
Batiz, L. F. (Principal Investigator) & Luarte Navarro, A. E. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/25 → 31/03/29
Project: RESEARCH
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EXPLORACIÓN - 3240026: INTELLIGENCE COSTS ENERGY: A BRAIN- INSPIRED APPROACH TO A MORE SUSTAINABLE ARTIFICIAL INTELLIGENCE
Maldonado, P. E. (Principal Investigator) & Luarte Navarro, A. E. (Principal Investigator)
1/11/24 → 1/11/27
Project: RESEARCH
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DESAFÍO GLOBAL EN LONGEVIDAD SALUDABLE - S/I: CATCH IT EARLY: REVOLUTIONIZING DIFFERENTIAL MILD COGNITIVE IMPAIRMENT DIAGNOSIS WITH CELLULAR SENSORS FOR EARLY DETECTION OF ALZHEIMER’S DISEASE AND NEURODEGENERATION
Wyneken, Ú. (Director), Luarte Navarro, A. E. (Alternate Director), Ramírez Lobos, V. (Principal Investigator) & Perez, C. A. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/12/23 → 30/12/24
Project: INNOVACIÓN Y DESARROLLO
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FONDECYT INICIACIÓN - 11220601: EXPLORING THE CONTRIBUTION OF ASTROCYTE-DERIVED EXTRACELLULAR VESICLES TO CONTROL AXONAL PROTEIN SYNTHESIS BY MICRORNA TRANSFER
Luarte Navarro, A. E. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
15/03/22 → 14/03/25
Project: RESEARCH
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Correction: A novel brain-to-gut communication pathway mediated by astrocyte-derived small extracellular vesicles modulates stress-induced intestinal inflammation (Molecular Psychiatry, (2025), 30, 12, (5710-5721), 10.1038/s41380-025-03289-2)
Yantén-Fuentes, L., Pizarro, M., Rojas, C., Pradenas, C., Méndez-Ruette, M., Corvalán, K., Bustos-Quevedo, G., Luarte, A., Batiz, L. F., Luz-Crawford, P., Pino-Lagos, K. & Wyneken, U., Feb 2026, In: Molecular Psychiatry. 31, 2, p. 1201 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Deep learning-based differential diagnosis of major depression and bipolar disorder using microglia-cellular sensors and patient-derived small extracellular vesicles
Zambrano, J., Luarte, A., Contreras, J., Perez, J. P., Yantén-Fuentes, L., Prieto, M., Lazcano, P., Wyneken, U. & Perez, C. A., Dec 2026, In: Scientific Reports. 16, 1, 11679.Research output: Contribution to journal › Article › peer-review
Open Access -
Método Para Determinar El Riesgo De Padecer Enfermedades Asociadas A La Salud Mental Mediante El Análisis De Cambios Morfológicos En Células De Microglía
Luarte Navarro, A. (Inventor), Úrsula Wyneken Hempel, I. (Inventor), Luis Prieto Cancino, M. (Inventor), Francisco Delpiano Costabal, J. (Inventor), Lazcano García, P. (Inventor) & Muñoz Eichler, I. (Inventor), 31 Mar 2026, Patent No. EP 24 216 831.8, Priority date 1 Jan 2024, Priority No. EP 24 216 831.8Research output: Patent
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Reticulon-1 synthesis controls outgrowth and microtubule dynamics in injured cortical axons
Luarte, A., Gallardo, J., Corvalán, D., Chakraborty, A., Roque, C. G., Bertin, F., Contreras, C., Ramírez, J. P., Weber, A., Acevedo, W., Zuschratter, W., Herrera-Molina, R., Wyneken, Ú., Paula-Lima, A., Adasme-Rocha, T., Toledo, J., Vergara, R., Figueroa, A., González, C. & González-Billault, C. & 2 others, , Apr 2026, In: Life Science Alliance. 9, 4, e202503571.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel brain-to-gut communication pathway mediated by astrocyte-derived small extracellular vesicles modulates stress-induced intestinal inflammation
Yantén-Fuentes, L., Pizarro, M., Rojas, C., Pradenas, C., Méndez-Ruette, M., Corvalán, K., Bustos-Quevedo, G., Luarte, A., Batiz, L. F., Luz-Crawford, P., Pino-Lagos, K. & Wyneken, U., Dec 2025, In: Molecular Psychiatry. 30, 12, p. 5710-5721 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations