Alejandra Chaparro

2024

Knowledge and Experiences of Oral Health Care and Periodontitis of Caregivers of Older Adults With Cognitive Impairment

Prieto, D., Palacios, M., Wainstein, V., Ortuño, D., Mora, S., Chaparro, A. & Pascual, A., 2024, (Accepted/In press) In: Gerodontology.

Research output: Contribution to journal › Article › peer-review

Open Access

Proteomic Analysis of Salivary Extracellular Vesicles from COVID-19 Patients Reveals a Specific Anti-COVID-19 Response Protein Signature

Weber, L., Torres, A., Realini, O., Bendek, M. J., Mizgier, M. L., Brizuela, C., Herrera, D., González, F. E. & Chaparro, A., Apr 2024, In: International Journal of Molecular Sciences. 25, 7, p. 1-20 20 p., 3704.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Proteomic Insights Into Gingival Crevicular Extracellular Vesicles in Periodontitis and Gestational Diabetes: An Exploratory Study

Mizgier, M. L., Nardocci, G., Ramírez, V., Bendek, M. J., Hernández, M., Rojas, C., Herrera, D., Kantarci, A., Kemp, M. W., Illanes, S. E. & Chaparro, A., 2024, (Accepted/In press) In: Journal of Clinical Periodontology.

Research output: Contribution to journal › Article › peer-review

Strategies for the prevention of periodontal disease and its impact on general health: Latin America and the Caribbean Consensus 2024

DUQUE DUQUE, A., CHAPARRO PADILLA, A., ALMEIDA, M. L., MARÍN JARAMILLO, R. A., ROMANELLI, H. J. & LAFAURIE VILLAMIL, G. I., 2024, In: Brazilian Oral Research. 38, p. 1-13 13 p., e120.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

TNF-alpha gene promoter's hypomethylation mediates a pro-inflammatory phenotype in peripheral blood monocytes from apical periodontitis individuals

Fernández, A., Bordagaray, M. J., Garrido, M., Pellegrini, E., Baeza, M., Chaparro, A., Hernández, P. & Hernández, M., 2024, (Accepted/In press) In: International Endodontic Journal.

Research output: Contribution to journal › Article › peer-review

2023

Obesity is related to maternal periodontitis severity in pregnancy: a cross-sectional study

Ramírez, V., Weber, L., Hernández, M., Realini, O., Bendek, M. J., Busso, D., Hoare, A., Illanes, S. E. & Chaparro, A., Sep 2023, In: Clinical Oral Investigations. 27, 9, p. 5509-5518 10 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Osteoinductive Electrospun Scaffold Based on PCL-Col as a Regenerative Therapy for Peri-Implantitis

Sanhueza, C., Hermosilla, J., Klein, C., Chaparro, A., Valdivia-Gandur, I., Beltrán, V. & Acevedo, F., 12 Jul 2023, In: Pharmaceutics. 15, 7, p. 1-18 18 p., 1939.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Relationship between soluble neuropilin-1 in the gingival crevicular fluid of early pregnant women and different severities of periodontitis: a cross-sectional study

Prieto, D., Pino-Lagos, K., Realini, O., Cáceres, F., Retamal, I. & Chaparro, A., 1 Mar 2023, In: Journal of Oral Biology and Craniofacial Research. 13, 2, p. 321-326 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection in household contacts and related factors during the first and second waves of the COVID-19 pandemic in Chile: a longitudinal cohort study

Urquidi, C., Rebolledo, V., Chaparro, A., Gonzalez, I., Delgado, F., Realini, O., Valenzuela, M., Ventura, M., Brizuela Cordero, D., Reyes-López, F. & Sandino, A., 2023, In: Population Medicine. 5, p. 131 1 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

CpG Single-Site Methylation Regulates TLR2 Expression in Proinflammatory PBMCs From Apical Periodontitis Individuals

Bordagaray, M. J., Fernández, A., Astorga, J., Garrido, M., Hernández, P., Chaparro, A., Lira, M. J., Gebicke-Haerter, P. & Hernández, M., 1 Mar 2022, In: Frontiers in Immunology. 13, p. 1-3 9 p., 861665.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Exploring the Expression of Pro-Inflammatory and Hypoxia-Related MicroRNA-20a, MicroRNA-30e, and MicroRNA-93 in Periodontitis and Gingival Mesenchymal Stem Cells under Hypoxia

Chaparro, A., Lozano, M., Gaedechens, D., López, C., Albers, D., Hernández, M., Pascual, A., Nart, J. & Irarrazabal, C. E., 7 Sep 2022, In: International Journal of Molecular Sciences. 23, 18, p. 1-12 12 p., 10310.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Histological and Immunohistochemical Analysis of Peri-Implant Soft and Hard Tissues in Patients with Peri-Implantitis

Flores, V., Venegas, B., Donoso, W., Ulloa, C., Chaparro, A., Sousa, V. & Beltrán, V., 8 Jul 2022, In: International Journal of Environmental Research and Public Health. 19, 14, p. 1-9 9 p., 8388.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Molecular Biomarkers in Peri-Implant Health and Disease: A Cross-Sectional Pilot Study

Chaparro, A., Beltrán, V., Betancur, D., Sam, Y. H., Moaven, H., Tarjomani, A., Donos, N. & Sousa, V., 29 Aug 2022, In: International Journal of Molecular Sciences. 23, 17, p. 1-8 8 p., 9802.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2021

171P An unwelcome guest: P. gingivalis intratumoral infection and immune evasion in gastric cancer

Retamal, I. N., Muñoz Medel, M., Cáceres, M., Cereceda, K., Villarroel-Espíndola, F., Manque, P., Berkovits, A., Ríos, J. A., García-Bloj, B., Rodríguez, M. P., Corvalán, A. H., Owen, G. I., Armisén, R., Garrido, M. & Chaparro, A., Dec 2021, In: Annals of Oncology. 32, p. S1458

Research output: Contribution to journal › Article › peer-review

Active mmp-8 quantitative test as an adjunctive tool for early diagnosis of periodontitis

Hernández, M., Baeza, M., Räisänen, I. T., Contreras, J., Tervahartiala, T., Chaparro, A., Sorsa, T. & Hernández-Ríos, P., 20 Aug 2021, In: Diagnostics. 11, 8, p. 1-11 11 p., 1503.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Collagen quantification in peri-implant soft tissues in human peri-implantitis lesions

Flores, V., Venegas, B., Donoso, W., Ulloa, C., Chaparro, A., Sousa, V. & Beltrán, V., 1 Jun 2021, In: International Journal of Morphology. 39, 3, p. 683-687 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Early pregnancy levels of gingival crevicular fluid matrix metalloproteinases-8 and -9 are associated with the severity of periodontitis and the development of gestational diabetes mellitus

Chaparro, A., Realini, O., Hernández, M., Albers, D., Weber, L., Ramírez, V., Param, F., Kusanovic, J. P., Sorsa, T., Rice, G. E. & Illanes, S. E., 1 Feb 2021, In: Journal of Periodontology. 92, 2, p. 205-215 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Early pregnancy levels of gingival crevicular fluid matrix metalloproteinases-8 and -9 are associated with the severity of periodontitis and the development of gestational diabetes mellitus

Chaparro, A., Realini, O., Hernández, M., Albers, D., Weber, L., Ramírez, V., Param, F., Juan Pedro Kusanovic, P., Sorsa, T., Rice, G. E. & Illanes, S., Feb 2021, In: Journal of Periodontology. 92, 2, p. 205-215 11 p.

Research output: Contribution to journal › Article › peer-review

Gingival crevicular placental alkaline phosphatase is an early pregnancy biomarker for pre-eclampsia

Chaparro, A., Monckeberg, M., Realini, O., Hernández, M., Param, F., Albers, D., Ramírez, V., Kusanovic, J. P., Romero, R., Rice, G. & Illanes, S., 1 Apr 2021, In: Diagnostics. 11, 4, p. 1-12 12 p., 661.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Periodontal health and COVID-19 infection: a cohort study

Chaparro, A., Realini, O., Brizuela Cordero, D. & Urquidi Bellota, C., Aug 2021, In: International Association for Dental Research Chilean Division.

Research output: Contribution to journal › Article › peer-review

Periodontitis and gestational diabetes mellitus: A potential inflammatory vicious cycle

Bendek, M. J., Canedo-Marroquín, G., Realini, O., Retamal, I. N., Hernández, M., Hoare, A., Busso, D., Monteiro, L. J., Illanes, S. E. & Chaparro, A., 31 Oct 2021, In: International Journal of Molecular Sciences. 22, 21, p. 1-16 16 p., 11831.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Soluble Neuropilin-1 in gingival crevicular fluid from periodontitis patients: An exploratory cross-sectional study

Prieto, D., Maurer, G., Sáez, M., Cáceres Merino, F. A., Pino-Lagos, K. & Chaparro, A., 1 Jan 2021, In: Journal of Oral Biology and Craniofacial Research. 11, 1, p. 84-87 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Soluble neuropilin-1 in gingival crevicular fluid is associated with rheumatoid arthritis: An exploratory case-control study

Prieto, D., González, C., Weber, L., Realini, O., Pino-Lagos, K., Bendek, M. J., Retamal, I., Beltrán, V., Riedemann, J. P., Espinoza, F. & Chaparro, A., 1 Apr 2021, In: Journal of Oral Biology and Craniofacial Research. 11, 2, p. 303-307 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Systemic burden and cardiovascular risk to Porphyromonas species in apical periodontitis

Jiménez, C., Garrido, M., Pussinen, P., Bordagaray, M. J., Fernández, A., Vega, C., Chaparro, A., Hoare, A. & Hernández, M., 27 Jul 2021, (E-pub ahead of print) In: Clinical Oral Investigations. 26, 1, p. 993-1001 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

2020

Diagnostic potential of peri-implant crevicular fluid microRNA-21-3p and microRNA-150-5p and extracellular vesicles in peri-implant diseases

Chaparro, A., Atria, P., Realini, O., Monteiro, L. J., Betancur, D., Acuña-Gallardo, S., Ramírez, V., Bendek, M. J., Pascual, A., Nart, J., Beltrán, V. & Sanz, A., 13 Nov 2020, (E-pub ahead of print) In: Journal of Periodontology. p. e11-e21 11 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Inflammatory biomarkers in dentinal fluid as an approach to molecular diagnostics in pulpitis.

Brizuela, C., Meza, G., Mercadé, M., Inostroza, C., Chaparro, A., Bravo, I., Briceño, C., Hernández, M., Giner, L. & Ramírez, V., 1 Sep 2020, In: International Endodontic Journal. 53, 9, p. 1181-1191 11 p.

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

In situ endoscopic analysis of bone microstructure and vascularization in post-extraction sites immediately after a minimally invasive vertical tooth extraction in teeth with different periodontal status

Arraño, D., Chaparro, A., Lazzarini, M., Acuña-Mardones, P., Engelke, W. & Beltrán, V., Dec 2020, In: International Journal of Morphology. 38, 6, p. 1735-1741 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Lymphocyte b and th17 chemotactic cytokine levels in peri-implant crevicular fluid of patients with healthy, peri-mucositis, and peri-implantitis implants.

Chaparro, A., Sanz, A., Wolnitzky, A., Realini, O., Bendek, M. J., Betancur, D., Albers, D. & Beltrán, V., 1 Jul 2020, In: Journal of Oral Research. 2020, Special Issue 1, p. 20-25 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Mmp-8, trap-5, and opg levels in gcf diagnostic potential to discriminate between healthy patients’, mild and severe periodontitis sites

Hernández, M., Baeza, M., Contreras, J., Sorsa, T., Tervahartiala, T., Valdés, M., Chaparro, A. & Hernández-Ríos, P., Nov 2020, In: Biomolecules. 10, 11, p. 1-13 13 p., 1500.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Molecular signatures of extracellular vesicles in oral fluids of periodontitis patients

Chaparro Padilla, A., Weber Aracena, L., Realini Fuentes, O., Albers Busquetts, D., Hernández Ríos, M., Ramírez Lobos, V., Pascual La Rocca, A., Nart Molina, J., Beltrán Varas, V., Acuña-Gallardo, S. & Sanz Ruiz, A., 1 Sep 2020, In: Oral Diseases. 26, 6, p. 1318-1325 8 p.

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

2019

¿La periodontitis crónica modifica la morbilidad de la artritis reumatoide? Aspectos clínicos y moleculares. Una revisión sistemática

Translated title of the contribution: Association between chronic periodontitis and rheumatoid arthritis: A systematic reviewWen, S., Beltrán, V., Chaparro, A., Espinoza, F. & Riedemann, J. P., Jun 2019, In: Revista Medica de Chile. 147, 6, p. 762-775 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Association between the use of statins and periodontal status: a review

Rosenberg, D., Vega, M. P., Chaparro, A., Kernitsky, J., Andrade, C., Violant, D. & Nart, J., 2019, In: Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral. 12, 1, p. 41-46 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Elevated Systemic Inflammatory Burden and Cardiovascular Risk in Young Adults with Endodontic Apical Lesions

Garrido, M., Cárdenas, A. M., Astorga, J., Quinlan, F., Valdés, M., Chaparro, A., Carvajal, P., Pussinen, P., Huamán-Chipana, P., Jalil, J. E. & Hernández, M., Feb 2019, In: Journal of Endodontics. 45, 2, p. 111-115 5 p.

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

2018

Effect of two periodontal treatment modalities in patients with uncontrolled type 2 diabetes mellitus: A randomized clinical trial

Quintero, A. J., Chaparro, A., Quirynen, M., Ramirez, V., Prieto, D., Morales, H., Prada, P., Hernández, M. & Sanz, A., Sep 2018, In: Journal of Clinical Periodontology. 45, 9, p. 1098-1106 9 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Oral extracellular vesicles in early pregnancy can identify patients at risk of developing gestational diabetes mellitus

Monteiro, L. J., Varas-Godoy, M., Monckeberg, M., Realini, O., Hernández, M., Rice, G., Romero, R., Saavedra, J. F., Illanes, S. E. & Chaparro, A., 1 Jun 2018, In: PLoS ONE. 14, 6, e0218616.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Periodontitis and placental growth factor in oral fluids are early pregnancy predictors of gestational diabetes mellitus

Chaparro, A., Zúñiga, E., Varas-Godoy, M., Albers, D., Ramírez, V., Hernández, M., Kusanovic, J. P., Acuña-Gallardo, S., Rice, G. & Illanes, S. E., 2018, In: Journal of Periodontology. 89, 9, p. 1052-1060 9 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

2016

IFPA meeting 2015 workshop report II: mechanistic role of the placenta in fetal programming; biomarkers of placental function and complications of pregnancy

Andraweera, P. H., Bobek, G., Bowen, C., Burton, G. J., Correa Frigerio, P., Chaparro, A., Dickinson, H., Duncombe, G., Hyett, J., Illanes, S. E., Johnstone, E., Kumar, S., Morgan, T. K., Myers, J., Orefice, R., Roberts, C. T., Salafia, C. M., Thornburg, K. L., Whitehead, C. L. & Bainbridge, S. A., 1 Dec 2016, In: Placenta. 48, p. S7-S11 5 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Placental biomarkers and angiogenic factors in oral fluids of patients with preeclampsia

Chaparro, A., Gaedechens, D., Ramírez, V., Zuñiga, E., Kusanovic, J. P., Inostroza, C., Varas-Godoy, M., Silva, K., Salomon, C., Rice, G. & Illanes, S. E., 13 May 2016, (E-pub ahead of print) In: Prenatal Diagnosis. 36, 5, p. 476-482 7 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

2015

Cambios del estado clínico periodontal según consumo sistémico de estatinas

Translated title of the contribution: Changes in clinic periodontal status according to systemic statins intakeRosenberg, D., Andrade, C., Larrea, R. E., Chaparro, A., silva, C., Ramírez, V., Urquidi Bellota, C., Violant, D. & Nart, J., 15 Aug 2015, In: Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral. 8, 2, p. 111-116

Research output: Contribution to journal › Article › peer-review

Open Access

Detection of CD63+ micro-vesicles, placental alkaline phosphatase and angiogenic markers in gingival crevicular fluid in preeclamptic patients

Chaparro, A., Zúñiga, E., Gaedechens, D., Ramírez, V., silva, C., Juan Kusanovic, P., Silva, K., Rice, G. E. & Illanes, S., Sep 2015, In: Placenta. 9, 36, p. A53 1 p.

Research output: Contribution to journal › Article › peer-review

Mesenchymal stem cells from the oral cavity and their potential value in tissue engineering

Sanz, A. R., Carrión, F. S. & Chaparro, A. P., 1 Feb 2015, In: Periodontology 2000. 67, 1, p. 251-267 17 p.

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Root coverage of multiple Miller Class I and II recession defects using acellular dermal matrix and tunneling technique in maxilla and mandible: A 1-year report

Chaparro, A., De la Fuente, M., Albers, D., Hernandez, D., Villalobos, A. M., Gaedechens, D. & De la Fuente, M., 10 Sep 2015, In: International Journal of Periodontics and Restorative Dentistry. 35, 5, p. 638-645 8 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Short-term effects of 2% atorvastatin dentifrice as an adjunct to periodontal therapy: A randomized double-masked clinical trial

Rosenberg, D., Andrade, C. X., Chaparro, A., Inostroza Silva, C., Ramírez, V., Violant, D. & Narti, J., 1 May 2015, In: Journal of Periodontology. 86, 5, p. 623-630 8 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

2013

Expresión de citoquinas Th17 y su correlación con periodontopatógenos y el área periodontal inflamada en pacientes con periodontitis crónica

Translated title of the contribution: Th17 cytokines expression and its correlation with periodontopathogens and periodontal inflammed surface area (PISA) in patients with chronic periodontitisHerane, A., Chaparro, A., Sanz, A., Hernandez, M., Quintero, A. J., Gaedechens, D., Carrión, F. & Silva, C., Dec 2013, In: Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral. 6, 3, p. 109-113 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Increased inflammatory biomarkers in early pregnancy is associated with the development of pre-eclampsia in patients with periodontitis: A case control study

Chaparro, A., Sanz, A., Quintero, A., Inostroza, C., Ramirez, V., Carrion, F., Figueroa, F., Serra, R. & Illanes, S. E., Jun 2013, In: Journal of Periodontal Research. 48, 3, p. 302-307 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Porphyromonas gingivalis, Treponema denticola and toll-like receptor 2 are associated with hypertensive disorders in placental tissue: A case-control study

Chaparro, A., Blanlot, C., Ramírez, V., Sanz, A., Quintero, A., Inostroza, C., Bittner, M., Navarro, M. & Illanes, S. E., Dec 2013, In: Journal of Periodontal Research. 48, 6, p. 802-809 8 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Relación entre los niveles de compuestos volátiles sulfurados con los niveles de RANKL y OPG en pacientes con periodontitis crónica moderada o severa: estudio transversal

Translated title of the contribution: Relationship between the levels of volatile sulfur compounds with the levels of RANKL and OPG in patients with moderate or severe periodontitis: a cross sectional studyPrieto Damm, D. J., Sanz Ruiz, A., Chaparro, A., silva, C. & Ramírez, V., Apr 2013, In: Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral. 6, 1, p. 20-24 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2011

Asociación entre periodontitis crónica, interleuquina-6 (IL-6) e índice de masa corporal (IMC) en embarazadas

Translated title of the contribution: Association between chronic periodontitis, interleukin-6 (IL-6) and body mass index (BMI) in pregnant womenMella, S., silva, C., Sanz, A., Illanes, S., Carrión A, F., Ramírez, V. & Chaparro, A., Dec 2011, In: Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral. 4, 3, p. 97-101 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2010

Culture and characterization of mesenchymal stem cells from human gingival tissue

Mitrano, T. I., Grob, M. S., Carrion, F., Nova-Lamperti, E., Luz, P. A., Fierro, F. S., Quintero, A., Chaparro, A. & Sanz, A., Jun 2010, In: Journal of Periodontology. 81, 6, p. 917-925 9 p.

Research output: Contribution to journal › Article › peer-review

193 Scopus citations

2009

Relación entre enfermedad periodontal, infección bacteriana ascendente y patología placentaria con parto prematuro

Translated title of the contribution: Relationship between periodontal diseases and ascending bacterial infection with preterm deliveryOvalle, A., Gamonal, J., Martínez, M. A., Silva, N., Kakarieka, E., Fuentes, A., Chaparro, A., Gajardo, M., León, R., Ahumada, A. & Cisternas, C., Apr 2009, In: Revista Medica de Chile. 137, 4, p. 504-514 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Alejandra Chaparro, PhD

Research output

Search results