Projects per year
Personal profile
Professional Information
Dentist graduated from the University of Chile, Specialist in Periodontics from the same institution. After completing my specialty, I worked as a faculty member and researcher at the University of Chile, teaching in the undergraduate periodontics clinic and postgraduate programs. I have been interested in research since my undergraduate studies. Alongside my teaching and research activities, I have also been developing my clinical practice.
I have been working at the University of the Andes for 17 years, where I have served as an undergraduate professor in the field of periodontics. Later, we established the Postgraduate Specialty Program in Periodontics, in which I currently participate as a collaborating faculty member. I have also been involved in the Master’s in Research and Innovation in Dentistry, which I directed for a couple of years and currently participate in as a thesis advisor and faculty member. Additionally, I am part of the faculty of the Doctorate in Biomedicine and the Ph.D. in Dental Sciences.
In terms of university administration, I am currently the Head of the Department of Pathology and Conservative Dentistry and the Director of Research in the Faculty of Dentistry. I was also the President of the IADR-Chile Division, Vice President of the Periodontics Society, and currently serve as Director of the Scientific Committee of the Chilean Periodontics Society. Throughout my career, I have been awarded various grants and research projects from ANID and CORFO, where I act as the principal investigator and collaborate with researchers from different national and international universities, such as the Universidad de la Frontera, Universidad Austral, Universidad de Chile, and Universidad de Concepción.
Internationally, we have collaborations with institutions like the Complutense University, the International University of Catalonia, the University of Guarulhos, and Universidad El Bosque, among others. My clinical practice is carried out at the University of the Andes Clinic
Research interests
At present, we are conducting several ongoing research projects focused on investigating the relationship between periodontitis and diabetes, as well as periodontitis and neuroinflammation. Furthermore, we are exploring oral biomarkers through proteomic and transcriptomic techniques to enable the early and minimally invasive identification of peri-implantitis and various pregnancy-related conditions, such as preeclampsia and gestational diabetes, using oral fluids.
In addition, we are collaborating on studies examining biomarkers associated with pulp pathologies, the link between periapical disease and cardiovascular risk, and the development of regenerative scaffolds aimed at restoring periodontal and peri-implant tissues lost as a result of periodontal and peri-implant diseases.
Teaching
My teaching area focuses on the discipline of periodontics, which studies the supporting tissues of the teeth and their relationship with other systemic diseases. I participate in undergraduate courses but primarily in the postgraduate Periodontics program at our University, the Master's program in Research and Innovation, and the Doctoral programs in Biomedicine and Dental Sciences.
My research lines are related to periodontal medicine, biomarkers, precision dentistry, and the regeneration of periodontal tissues
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Master, Ciencias Odontológicas, mención en Periodoncia, Universidad Complutense de Madrid
PhD, Ciencias de la Salud, Universidad Internacional de Cataluña
University Degree, Cirujano Dentista, Universidad de Chile
Periodoncista, Universidad de Chile
External positions
Directora del Magister en Investigación e innovación en Ciencias de la Odontología, Universidad de los Andes Chile
2020 → 2023
Presidente, International Association for Dental Research (IADR), Chile
2018 → 2019
Vicepresidenta, Sociedad de Periodoncia de Chile
2014 → 2015
Habilitación para la dirección de tesis doctorales
- Habilitado
Proceso de habilitación doctoral
- HABILITACIÓN II-2024
Research Lines
- Research Lines
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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VIU - VIU24P0014: THE PATHOGENIC VICIOUS CYCLE BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES MELLITUS: COMMUNICATION VIA BACTERIAL TRANSLOCATION AND EXTRACELLULAR VESICLES
Bendek Viera, M. J. (Principal Investigator) & Chaparro, A. (Co-Investigator)
4/11/24 → …
Project: Research
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FONDECYT REGULAR - 1211471: THE PATHOGENIC VICIOUS CYCLE BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES MELLITUS: COMMUNICATION VIA BACTERIAL TRANSLOCATION AND EXTRACELLULAR VESICLES
Chaparro, A. (Principal Investigator), Busso, D. (Co-Investigator), Illanes, S. (Co-Investigator), Ramirez Lobos, V. (Co-Investigator), Hernández Ríos, E. (Co-Investigator) & Hoare, A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT POSTDOCTORADO - 3240581: Exploring the effect of periodontitis-derived extracellular vesicles on microglial polarization and regulatory T cells neuroprotective function impairment in the brain. A possible link between Periodontitis and Neuroinflammation?
Chaparro, A. (Sponsoring Researcher) & Rojas, C. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo (ANID)
Project: Research
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FAI ATP MICARE - INV-ATP MICARE-2023-01: IMPACTO DE UN PROGRAMA DE EDUCACIÓN EN SALUD ORAL DIRIGIDO A CUIDADORES DE PERSONAS MAYORES CON DISTINTOS GRADOS DE DETERIORO COGNITIVO EN EL CONTROL DEL BIOFILM DENTAL
Prieto Damm, D. J. (Principal Investigator) & Chaparro, A. (Co-Investigator)
Universidad de los Andes Chile
1/10/23 → 1/10/24
Project: Research
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FAI INSCRIPCION CONGRESO - APO-CG-2023-28: INCREASED GINGIVAL CREVICULAR FLUID EXTRACELLULAR VESICLES ARE INVOLVED IN THE CROSSTALK BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES
Mizgier, M. L. (Principal Investigator), Realini, O. (Co-Investigator), Bendek Viera, M. J. (Co-Investigator), Rojas Pérez, C. I. (Co-Investigator), Monje, S. (Co-Investigator), Figari, A. (Co-Investigator), Hernández, M. (Co-Investigator), Ramírez Lobos, V. (Co-Investigator), Illanes, S. (Co-Investigator), Busso, D. (Co-Investigator) & Chaparro, A. (Co-Investigator)
Universidad de los Andes Chile
4/09/23 → 30/12/23
Project: Research
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Knowledge and Experiences of Oral Health Care and Periodontitis of Caregivers of Older Adults With Cognitive Impairment
Prieto, D., Palacios, M., Wainstein, V., Ortuño, D., Mora, S., Chaparro, A. & Pascual, A., 2024, (Accepted/In press) In: Gerodontology.Research output: Contribution to journal › Article › peer-review
Open Access -
MicroRNAs: the Missing Link between Hypertension and Periodontitis?
Rodriguez, N. M., Loren, P., Paez, I., Martínez, C., Chaparro, A. & Salazar, L. A., 6 Feb 2024, In: International Journal of Molecular Sciences. 25, 4, p. 1-25 25 p., 1992.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Proteomic Analysis of Salivary Extracellular Vesicles from COVID-19 Patients Reveals a Specific Anti-COVID-19 Response Protein Signature
Weber, L., Torres, A., Realini, O., Bendek, M. J., Mizgier, M. L., Brizuela, C., Herrera, D., González, F. E. & Chaparro, A., Apr 2024, In: International Journal of Molecular Sciences. 25, 7, p. 1-20 20 p., 3704.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Proteomic Insights Into Gingival Crevicular Extracellular Vesicles in Periodontitis and Gestational Diabetes: An Exploratory Study
Mizgier, M. L., Nardocci, G., Ramírez, V., Bendek, M. J., Hernández, M., Rojas, C., Herrera, D., Kantarci, A., Kemp, M. W., Illanes, S. E. & Chaparro, A., 2024, (Accepted/In press) In: Journal of Clinical Periodontology.Research output: Contribution to journal › Article › peer-review
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Strategies for the prevention of periodontal disease and its impact on general health: Latin America and the Caribbean Consensus 2024
DUQUE DUQUE, A., CHAPARRO PADILLA, A., ALMEIDA, M. L., MARÍN JARAMILLO, R. A., ROMANELLI, H. J. & LAFAURIE VILLAMIL, G. I., 2024, In: Brazilian Oral Research. 38, p. 1-13 13 p., e120.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Courses
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DOCB1210 Avances Biotecnológicos en Medicina
Course
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DOCB3364 Tópicos Avanzados en Biomedicina: Contenido Optativo
J. Monteiro, L., Busso, D., Illanes, S., Batiz, L. F., Chaparro, A. & Monckeberg, M. 20/08/20 → 14/12/20
Course
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Press/Media
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A más de la mitad de los chilenos les sangran las encías al cepillarse
30/04/24 → 22/05/24
8 items of Media coverage
Press/Media: Vinculación con el medio a través de medios de comunicación social
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Para qué sirve el enjuague bucal y cómo debes usarlo
22/04/22
1 item of Media coverage
Press/Media: Vinculación con el medio a través de medios de comunicación social
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Universidad de los Andes abordó los avances sobre los biomarcadores para diagnosticar enfermedades
19/11/21
1 item of Media coverage
Press/Media: Vinculación con el medio a través de medios de comunicación social
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Alejandra Chaparro se adjudica fondos para investigar sobre Covid-19
2/07/20
1 item of Media coverage
Press/Media: Vinculación con el medio a través de medios de comunicación social
Impacts
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Biomarcadores para diagnóstico de enfermedades futuras.
Chaparro, A. (Participant)
Impact: Social impacts
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Conferencia "Biomarcadores para diagnosticar enfermedades en un futuro" presentada en 4ta edición de Protagonistas 2030
Chaparro, A. (Participant)
Impact: Social impacts
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La cavidad oral como reservorio del SARS CoV-2: detección temprana de adultos asintomáticos y análisis de inmunidad en muestras de saliva
Chaparro, A. (Participant)
Impact: Social impacts
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