Projects per year
Personal profile
Research Interests
Neuroscientist interested in the study of stress effects on the central nervous system. In particular, we have been focusing on molecular pathways that participate in the axis from the brain to peripheral organs and that contribute to the high co-morbidity among stress-induced pathologies. In that line, we also study peripheral biomarkers that are associated to neuropsychiatric disorders.
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Dive into the research topics where Úrsula Wyneken is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT)
Khoury, M., Alcayaga-Miranda, F., Cuenca, J., Acevedo, J. P., Figueroa, F., Luz Crawford, P. A., Wyneken, Ú., Illanes, S., Batiz, L. F., Busso, D., J. Monteiro, L., Nardocci, G., Enrione, J. I., Espinoza, F., Valenzuela Bravo, M. T. & Prieto, M.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/11/21 → 31/10/26
Project: Research
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Prenatal stress: Maternal astrocyte-derived extracellular vesicles as a novel stress-transfer mechanism contributing to adverse offspring neurodevelopment
Batiz, L. F., Nardocci, G., Wyneken, Ú., Illanes, S., J. Monteiro, L. & Caradeux, J.
Agencia Nacional de Investigación y Desarrollo (ANID), Chile
1/01/21 → 1/01/25
Project: Research
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Sumoylation in astrocytes induces changes in the proteome of the derived small extracellular vesicles which change protein synthesis and dendrite morphology in target neurons
Fernandez, A., Corvalan, K., Santis, O., Mendez-Ruette, M., Caviedes, A., Pizarro, M., Gomez, M. T., Batiz, L. F., Landgraf, P., Kahne, T., Rojas-Fernandez, A. & Wyneken, U., 15 Jan 2024, In: Brain Research. 1823, 148679.Research output: Contribution to journal › Article › peer-review
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Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK
Bustamante-Barrientos, F. A., Méndez-Ruette, M., Molina, L., Koning, T., Ehrenfeld, P., González, C. B., Wyneken, U., Henzi, R. & Bátiz, L. F., 2023, In: Frontiers in Cell and Developmental Biology. 11, p. 1061777 1061777.Research output: Contribution to journal › Article › peer-review
Open Access -
Astrocyte-derived extracellular vesicles in stress-associated mood disorders. Does the immune system get astrocytic?
Luarte, A., Nardocci, G., Chakraborty, A., Batiz, L. F., Pino-Lagos, K. & Wyneken, Ú., Aug 2023, In: Pharmacological Research. 194, 106833.Research output: Contribution to journal › Review article › peer-review
Open Access -
Cannabinoid regulation of neurons in the dentate gyrus during epileptogenesis: Role of CB1R-associated proteins and downstream pathways
Lafourcade, C. A., Sparks, F. T., Bordey, A., Wyneken, U. & Mohammadi, M. H., 2023, In: Epilepsia.Research output: Contribution to journal › Article › peer-review
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Behavioral and Molecular Responses to Exogenous Cannabinoids During Pentylenetetrazol-Induced Convulsions in Male and Female Rats
Zirotti Rosenberg, A., Méndez-Ruette, M., Gorziglia, M., Alzerreca, B., Cabello, J., Kaufmann, S., Rambousek, L., Iturriaga Jofré, A., Wyneken, U. & Lafourcade, C. A., 9 Aug 2022, In: Frontiers in Molecular Neuroscience. 15, p. 868583 868583.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Activities
- 3 Oral presentation
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The M105I mutation of alpha-SNAP leads to increased levels of pAMPK affecting the mitochondrial homeostasis and the balance between proliferation and differentiation of neural stem/progenitor cells
Roberto Henzi (Keynote speaker), Felipe A. Bustamante (Speaker), Maxs Méndez (Speaker), Úrsula Wyneken (Speaker) & Luis Federico Batiz (Speaker)
2021Activity: Talk or presentation › Oral presentation
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SUMOylation determines the protein cargo of astrocyte-derived small extracellular vesicles
Maxs Méndez (Keynote speaker), Anllely Fernández (Speaker), Luis Federico Batiz (Speaker), Roberto Henzi (Speaker), Alejandro Rojas-Fernández (Speaker) & Úrsula Wyneken (Speaker)
2019Activity: Talk or presentation › Oral presentation
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Maternal brain-to-fetal brain communication mediated by small extracellular vesicles: Possible role in prenatal stress
Lorena Abarzua-Catalan (Speaker), Roberto Henzi (Speaker), Úrsula Wyneken (Speaker), Sebastián Illanes (Speaker) & Luis Federico Batiz (Keynote speaker)
2019Activity: Talk or presentation › Oral presentation
Courses
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DOCB1210 Avances Biotecnológicos en Medicina
Course