Projects per year
Personal profile
Additional Research Interests
Neuroscientist interested in the study of stress effects on the central nervous system. In particular, we have been focusing on molecular pathways that participate in the axis from the brain to peripheral organs and that contribute to the high co-morbidity among stress-induced pathologies. In that line, we also study peripheral biomarkers that are associated to neuropsychiatric disorders.
Education/Academic qualification
PhD, Ciencias Biomédicas, Universidad de Chile
… → 1996
University Degree, Bioquímica, Universidad de Chile
Research Lines
- Research Lines
Fingerprint
Dive into the research topics where Úrsula Wyneken is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FONDECYT REGULAR - 1240604: Brain astrocyte-derived extracellular vesicles orchestrate macrophage and microglia polarization under stress conditions through miRNA-dependent regulation of macrophage immunometabolism regulator (MACIR)
Wyneken, Ú. (Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Hidalgo, Y. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/24 → 31/03/28
Project: Research
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IMPACT: CENTER OF INTERVENTIONAL MEDICINE FOR PRECISION AND ADVANCED CELLULAR THERAPY
Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. (Associate Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/21 → 31/10/26
Project: Research
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Uso de exosomas de células madre mesenquimales en el tratamiento de la epilepsia: prevención de muerte neuronal
Wyneken, Ú. (Principal Investigator)
Project: Research
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FONDECYT REGULAR - 1210654: SMALL EXTRACELLULAR VESICLES OBTAINED FROM NEUROPILIN-1+ T REGULATORY CELLS AS A NOVEL TOOL FOR THE INDUCTION OF TRANSPLANTATION TOLERANCE
Pino-Lagos, K. (Principal Investigator) & Wyneken, Ú. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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Bulk serum extracellular vesicles from stressed mice show a distinct proteome and induce behavioral and molecular changes in naive mice
Monteleone, M. C., Billi, S. C., Abarzúa-Catalán, L., Henzi, R., Fernández, E. M., Kaehne, T., Wyneken, U. & Brocco, M. A., 1 Aug 2024, In: PLoS ONE. 19, 8, e0308976.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial: Medicinal drugs, the effect on memories and beyond
Moreira-Rodrigues, M., Ampuero, E. & Wyneken, U., 2024, In: Frontiers in Pharmacology. 15, 1471049.Research output: Contribution to journal › Editorial
Open Access1 Scopus citations -
Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice
Acuña-Catalán, D., Shah, S., Wehrfritz, C., Nomura, M., Acevedo, A., Olmos, C., Quiroz, G., Huerta, H., Bons, J., Ampuero, E., Wyneken, U., Sanhueza, M., Arancibia, F., Contreras, D., Cárdenas, J. C., Morales, B., Schilling, B., Newman, J. C. & González-Billault, C., 18 Jun 2024, In: Cell Reports Medicine. 5, 6, 101593.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Maternal stress during pregnancy alters circulating small extracellular vesicles and enhances their targeting to the placenta and fetus
Sánchez-Rubio, M., Abarzúa-Catalán, L., del Valle, A., Méndez-Ruette, M., Salazar, N., Sigala, J., Sandoval, S., Godoy, M. I., Luarte, A., Monteiro, L. J., Romero, R., Choolani, M. A., Wyneken, Ú., Illanes, S. E. & Bátiz, L. F., Dec 2024, In: Biological Research. 57, 1, 70.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Methadone directly impairs central nervous system cells in vitro
De Gregorio, C., Gallardo, J., Berríos-Cárcamo, P., Handy, Á., Santapau, D., González-Madrid, A., Ezquer, M., Morales, P., Luarte, A., Corvalán, D., Wyneken, Ú. & Ezquer, F., Dec 2024, In: Scientific Reports. 14, 1, 16978.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Activities
- 3 Oral presentation
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The M105I mutation of alpha-SNAP leads to increased levels of pAMPK affecting the mitochondrial homeostasis and the balance between proliferation and differentiation of neural stem/progenitor cells
Henzi, R. (Keynote speaker), Bustamante, F. A. (Speaker), Méndez, M. (Speaker), Wyneken, Ú. (Speaker) & Batiz, L. F. (Speaker)
2021Activity: Talk or presentation › Oral presentation
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SUMOylation determines the protein cargo of astrocyte-derived small extracellular vesicles
Méndez, M. (Keynote speaker), Fernández, A. (Speaker), Batiz, L. F. (Speaker), Henzi, R. (Speaker), Rojas-Fernández, A. (Speaker) & Wyneken, Ú. (Speaker)
2019Activity: Talk or presentation › Oral presentation
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Maternal brain-to-fetal brain communication mediated by small extracellular vesicles: Possible role in prenatal stress
Abarzua-Catalan, L. (Speaker), Henzi, R. (Speaker), Wyneken, Ú. (Speaker), Illanes, S. (Speaker) & Batiz, L. F. (Keynote speaker)
2019Activity: Talk or presentation › Oral presentation
Courses
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DOCB1110 Biología Celular y Molecular en Biomedicina
J. Monteiro, L., Nardocci, G., Batiz, L. F., Busso, D., Acevedo, J. P., Luz Crawford, P. A. & Wyneken, Ú. 22/03/21 → 30/06/21
Course
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DOCB1210 Avances Biotecnológicos en Medicina
Course