Projects per year
Search results
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Active
FONDECYT REGULAR - 1240604: Brain astrocyte-derived extracellular vesicles orchestrate macrophage and microglia polarization under stress conditions through miRNA-dependent regulation of macrophage immunometabolism regulator (MACIR)
Wyneken, Ú. (Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Hidalgo, Y. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/24 → 31/03/28
Project: Research
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FONDECYT REGULAR - 1230875: REVEALING THE CONTRIBUTION OF MELANOMA-DERIVED CIRCULATING CELL-FREE MITOCHONDRIA IN THE FORMATION OF PREMETASTATIC NICHE IN LYMPH NODES AND THEIR IMPACT IN THE EARLY DEVELOPMENT OF METASTASIS
Alcayaga-Miranda, F. (Principal Investigator), Khoury, M. (Co-Investigator), Pino-Lagos, K. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & González-Arriagada, W. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/23 → 31/03/27
Project: Research
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FONDECYT REGULAR - 1230932: THE POTENTIAL ROLE OF MENSTRUAL MESENCHYMAL STEM CELLS IN THE ETIOPATHOLOGY OF ENDOMETRIOSIS AND ITS ASSOCIATION WITH IMPAIRED ENDOMETRIUM RECEPTIVITY
J. Monteiro, L. (Principal Investigator), Donoso, M. B. (Co-Investigator), Vega-Letter, A. M. (Co-Investigator), Illanes, S. (Co-Investigator) & Luz Crawford, P. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/23 → 31/03/27
Project: Research
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FONDECYT POSTDOCTORADO - 3220204: TRANSFERENCIA MITOCONDRIAL DESDE CÉLULAS MADRE MESENQUIMALES COMO UNA NUEVA ALTERNATIVA TERAPÉUTICA PARA DESÓRDENES DEL NEURODESARROLLO: RELEVANCIA EN EL RESCATE METABÓLICO Y FUNCIONAL DE CÉLULAS MADRE NEURALES
Luz Crawford, P. A. (Sponsoring Researcher) & Bustamante, F. A. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo (ANID)
15/04/22 → 14/04/25
Project: Research
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IMPACT: CENTER OF INTERVENTIONAL MEDICINE FOR PRECISION AND ADVANCED CELLULAR THERAPY
Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. (Associate Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/21 → 31/10/26
Project: Research
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FONDECYT REGULAR - 1211353: INVESTIGATING THE IMMUNOREGULATORY AND ANTI-RHEUMATOID ARTHRITIS ACTIVITIES OF SMALL EXTRACELLULAR VESICLES-SHUTTLED BIOACTIVE MICRORNA DERIVED FROM GLYCOLYTIC MESENCHYMAL STEM CELL
Luz Crawford, P. A. (Principal Investigator), Khoury, M. (Co-Investigator), Alcayaga-Miranda, F. (Co-Investigator), Elizondo-Vega, R. (Co-Investigator), Altamirano, C. (Co-Investigator) & Nova-Lamperti, E. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1211376: INVESTIGATING THE EFFECT OF MAVS-ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRAL-INDUCED ACUTE LUNG INJURY MODEL.
Cuenca, J. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Khoury, M. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & Kurte, M. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1210654: SMALL EXTRACELLULAR VESICLES OBTAINED FROM NEUROPILIN-1+ T REGULATORY CELLS AS A NOVEL TOOL FOR THE INDUCTION OF TRANSPLANTATION TOLERANCE
Pino-Lagos, K. (Principal Investigator) & Wyneken, Ú. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1211749: IMPACT OF HORIZONTAL ARTIFICIAL TRANSFER OF MITOCHONDRIA ON UMBILICAL CORD BLOOD TRANSPLANTATION AND ITS CLINICAL RELEVANCE IN GRAFT VERSUS HOST DISEASE.
Khoury, M. (Principal Investigator), Luz Crawford, P. A. (Co-Investigator), Court, A. C. (Co-Investigator) & Figueroa, F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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Franco-Chilean initiative for Intra-Mitochondrial microRNAs as new mediators of mesenchymal stem cells immunoregulatory functions
Luz Crawford, P. A. (Principal Investigator)
1/03/21 → 28/02/25
Project: Research
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Millennium Institute on Immunology and Immunotherapy (IMII)
Kalergis, A. M. (Principal Investigator) & Luz Crawford, P. A. (Co-Investigator)
1/09/11 → 1/09/31
Project: Research
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Finished
Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis
Luz Crawford, P. A. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Elizondo-Vega, R. J. (Co-Investigator), Espinoza, F. (Co-Investigator) & Matas, J. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/21 → 30/11/23
Project: Research
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Metabolic reprograming of effector CD4+T cells by mitochondrial mediated-signalling in oral cancer and its effect upon T helper and T-dependent B cell responses
Nova, E. (Principal Investigator) & Luz Crawford, P. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/03/21 → 29/02/24
Project: Research
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Immunoregulatory and anti-rheumatoid arthritis activities of small extracellular vesicles-shuttled bioactive microRNA derived from glycolytic mesenchymal stem cells
Luz Crawford, P. A. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/03/21 → 29/02/24
Project: Research
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FONDECYT REGULAR - 1201420: Mitochondrial transfer within the osteoarthritic joint: restoration of the dysfunctional stress-response and metabolic pathway in cartilage in-vitro and in an animal model of disease
Figueroa, F. (Principal Investigator), Khoury, M. (Co-Investigator), Luz Crawford, P. A. (Co-Investigator) & Court, A. C. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/20 → 31/03/24
Project: Research
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FONDECYT REGULAR - 1201851: Role of mesenchymal stem cells in implantation and their contribution to the decidualization disorders present in preeclampsia
Illanes, S. (Principal Investigator), Pino-Lagos, K. (Co-Investigator), J. Monteiro, L. (Co-Investigator) & Acuña, S. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/20 → 31/03/23
Project: Research
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FONDECYT REGULAR - 1200693: Brain astrocyte-derived extracellular vesicles promote protective Treg induction in the GALT and restore gut tolerance in stressed rats
Wyneken, Ú. (Principal Investigator), Batiz, L. F. (Co-Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Batiz, L. F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/20 → 31/03/24
Project: Research
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Mitochondrial transfer from mesenchymal stem cells for osteoarthritis treatment
Figueroa, F. (Principal Investigator) & Luz Crawford, P. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/03/20 → 28/02/23
Project: Research
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Regulation of mesenchymal stem cell metabolic status to increase their immunosuppresive potential
Luz Crawford, P. A. (Principal Investigator)
1/04/19 → 31/03/21
Project: Research
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FONDECYT REGULAR - 1190411: Investigating the anti-angiogenic effect of exosome-mediated delivery of functionally active miRNA-149-3p,145-5p and 6131 to tumor tissue
Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Co-Investigator), Khoury, M. (Co-Investigator) & Pino-Lagos, K. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/19 → 15/04/23
Project: Research
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Regulation of mesenchymal stem cells metabolic status to improve their therapeutic potential for arthritis
Luz Crawford, P. A. (Principal Investigator)
1/01/19 → 31/12/20
Project: Research
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FONDECYT REGULAR - 1170852: Functional impact of MSC mitochondrial transfer to T lymphocytes and its clinical relevance in a Graft versus Host Disease
Khoury, M. (Principal Investigator), Luz Crawford, P. A. (Co-Investigator), Pino-Lagos, K. (Co-Investigator) & Figueroa, F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/17 → 31/03/21
Project: Research
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FONDECYT INICIACIÓN - 11160929: Study of the metabolic plasticity of mesenchymal stem cells and its role in their immunomodulatory effects on pathogenic T cells: Toward an optimization of their therapeutic potential for autoimmune diseases.
Luz Crawford, P. A. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/16 → 31/10/19
Project: Research
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Efecto Paradójico de Células Madre Mesenquimales sobre Linfocitos Th17 en animales con Encefalitis Autoinmune Experimental Sometidos a Tratamiento Inmunosupresor
Kurte, M. & Carrión, F.
Universidad de los Andes Chile
8/03/10 → 8/08/11
Project: Research