Projects per year
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FONDECYT REGULAR - 1240604: Brain astrocyte-derived extracellular vesicles orchestrate macrophage and microglia polarization under stress conditions through miRNA-dependent regulation of macrophage immunometabolism regulator (MACIR)
Wyneken, Ú. (Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Hidalgo, Y. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/24 → 31/03/28
Project: Research
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FONDECYT REGULAR - 1241103: DECIPHERING THE ROLE OF MITOCHONDRIAL TRANSFER IN THE PATHOPHYSIOLOGY OF PREECLAMPSIA
Illanes, S. (Principal Investigator), J. Monteiro, L. (Co-Investigator), Nardocci, G. (Co-Investigator) & Acuña, S. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/24 → 31/03/28
Project: Research
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FONDEF IDEA I+D 2023 - 23I10325: Desarrollo de un producto alogénico basado en un hidrogel bioactivo con nanovesículas extracelulares y su validación como tratamiento endodóntico regenerativo
Cuenca, J. (Principal Investigator), Brizuela Cordero, C. I. (Alternate Director), Khoury, M. (Co-Investigator), Alcayaga-Miranda, F. (Co-Investigator), Canedo Marroquin, G. (Co-Investigator) & González-Arriagada, W. A. (Co-Investigator)
National Agency for Research and Development (ANID)
15/06/23 → 15/06/25
Project: Research
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FONDECYT POSTDOCTORADO - 3230322: LA EXPRESIÓN DE HSP70 EN LA MEMBRANA DE VESÍCULAS EXTRACELULARES PREVIENEN EL DAÑO RENAL INDUCIDO POR ISQUEMIA/REPERFUSIÓN EN RATÓN.
Irarrazabal Muñoz, C. E. (Sponsoring Researcher) & Soto, P. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo (ANID)
15/04/23 → 14/04/26
Project: Research
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FONDECYT POSTDOCTORADO - 3230447: TRASPLANTE DE MITOCONDRIAS RESISTENTES A LA HIPOXIA: UNA PROMETEDORA TERAPIA CONTRA LA HIPERTENSIÓN PULMONAR HIPÓXICA
Cuenca, J. (Sponsoring Researcher) & Castillo, S. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo (ANID)
15/04/23 → 14/04/26
Project: Research
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FONDECYT POSTDOCTORADO - 3230201: ROLE OF BASIGIN ON TROPHOBLAST INVASION REGULATED THROUGH EXTRACELULLAR VESICLES RELEASED FROM ENDOMETRIAL MESENCHYMAL STEM CELLS
Illanes, S. (Sponsoring Researcher) & Peñailillo, R. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo (ANID)
15/04/23 → 14/04/26
Project: Research
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FONDECYT REGULAR - 1230932: THE POTENTIAL ROLE OF MENSTRUAL MESENCHYMAL STEM CELLS IN THE ETIOPATHOLOGY OF ENDOMETRIOSIS AND ITS ASSOCIATION WITH IMPAIRED ENDOMETRIUM RECEPTIVITY
J. Monteiro, L. (Principal Investigator), Donoso, M. B. (Co-Investigator), Vega-Letter, A. M. (Co-Investigator), Illanes, S. (Co-Investigator) & Luz Crawford, P. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/23 → 31/03/27
Project: Research
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FONDECYT REGULAR - 1230875: REVEALING THE CONTRIBUTION OF MELANOMA-DERIVED CIRCULATING CELL-FREE MITOCHONDRIA IN THE FORMATION OF PREMETASTATIC NICHE IN LYMPH NODES AND THEIR IMPACT IN THE EARLY DEVELOPMENT OF METASTASIS
Alcayaga-Miranda, F. (Principal Investigator), Khoury, M. (Co-Investigator), Pino-Lagos, K. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & González-Arriagada, W. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/23 → 31/03/27
Project: Research
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FONDECYT POSTDOCTORADO - 3220204: TRANSFERENCIA MITOCONDRIAL DESDE CÉLULAS MADRE MESENQUIMALES COMO UNA NUEVA ALTERNATIVA TERAPÉUTICA PARA DESÓRDENES DEL NEURODESARROLLO: RELEVANCIA EN EL RESCATE METABÓLICO Y FUNCIONAL DE CÉLULAS MADRE NEURALES
Luz Crawford, P. A. (Sponsoring Researcher) & Bustamante, F. A. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo (ANID)
15/04/22 → 14/04/25
Project: Research
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FONDECYT REGULAR - 1221376: UNCOVERING MECHANISMS CONTRIBUTING TO EXCENCEPHALY AND ITS PREVENTION BY MATERNAL VITAMIN E SUPPLEMENTATION IN HDL RECEPTOR SR-B1 KO MOUSE EMBRYOS
Busso, D. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/22 → 31/03/26
Project: Research
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FONDECYT INICIACIÓN - 11220601: EXPLORING THE CONTRIBUTION OF ASTROCYTE-DERIVED EXTRACELLULAR VESICLES TO CONTROL AXONAL PROTEIN SYNTHESIS BY MICRORNA TRANSFER
Luarte Navarro, A. E. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
15/03/22 → 14/03/25
Project: Research
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IMPACT: CENTER OF INTERVENTIONAL MEDICINE FOR PRECISION AND ADVANCED CELLULAR THERAPY
Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. (Associate Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/21 → 31/10/26
Project: Research
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FONDECYT REGULAR - 1210654: SMALL EXTRACELLULAR VESICLES OBTAINED FROM NEUROPILIN-1+ T REGULATORY CELLS AS A NOVEL TOOL FOR THE INDUCTION OF TRANSPLANTATION TOLERANCE
Pino-Lagos, K. (Principal Investigator) & Wyneken, Ú. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL
Cuenca, J. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Khoury, M. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & Kurte, M. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1211384: PRENATAL STRESS: MATERNAL ASTROCYTE-DERIVED EXTRACELLULAR VESICLES AS A NOVEL STRESS-TRANSFER MECHANISM CONTRIBUTING TO ADVERSE OFFSPRING NEURODEVELOPMENT
Batiz, L. F. (Principal Investigator), Nardocci, G. (Co-Investigator), Wyneken, Ú. (Co-Investigator), Illanes, S. (Co-Investigator), J. Monteiro, L. (Co-Investigator) & Caradeux, J. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1211471: THE PATHOGENIC VICIOUS CYCLE BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES MELLITUS: COMMUNICATION VIA BACTERIAL TRANSLOCATION AND EXTRACELLULAR VESICLES
Chaparro, A. (Principal Investigator), Busso, D. (Co-Investigator), Illanes, S. (Co-Investigator), Ramirez Lobos, V. (Co-Investigator), Hernández Ríos, E. (Co-Investigator) & Hoare, A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1211749: IMPACT OF HORIZONTAL ARTIFICIAL TRANSFER OF MITOCHONDRIA ON UMBILICAL CORD BLOOD TRANSPLANTATION AND ITS CLINICAL RELEVANCE IN GRAFT VERSUS HOST DISEASE.
Khoury, M. (Principal Investigator), Luz Crawford, P. A. (Co-Investigator), Court, A. C. (Co-Investigator) & Figueroa, F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1211353: INVESTIGATING THE IMMUNOREGULATORY AND ANTI-RHEUMATOID ARTHRITIS ACTIVITIES OF SMALL EXTRACELLULAR VESICLES-SHUTTLED BIOACTIVE MICRORNA DERIVED FROM GLYCOLYTIC MESENCHYMAL STEM CELL
Luz Crawford, P. A. (Principal Investigator), Khoury, M. (Co-Investigator), Alcayaga-Miranda, F. (Co-Investigator), Elizondo-Vega, R. (Co-Investigator), Altamirano, C. (Co-Investigator) & Nova-Lamperti, E. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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FONDECYT REGULAR - 1211376: INVESTIGATING THE EFFECT OF MAVS-ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRAL-INDUCED ACUTE LUNG INJURY MODEL.
Cuenca, J. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Khoury, M. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & Kurte, M. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
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Franco-Chilean initiative for Intra-Mitochondrial microRNAs as new mediators of mesenchymal stem cells immunoregulatory functions
Luz Crawford, P. A. (Principal Investigator)
1/03/21 → 28/02/25
Project: Research
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Millennium Institute on Immunology and Immunotherapy (IMII)
Kalergis, A. M. (Principal Investigator) & Luz Crawford, P. A. (Co-Investigator)
1/09/11 → 1/09/31
Project: Research