Medicina

Projects

Projects per year 1999 2012 2019 2020 2021 2031

• 14 Active
• 49 Finished

Projects per year

Search results

• Active

  Project Number: ID23I10325: Desarrollo de un producto alogénico basado en un hidrogel bioactivo con nanovesículas extracelulares y su validación como tratamiento endodóntico regenerativo

  Cuenca, J., Brizuela Cordero, C., Khoury, M., Alcayaga-Miranda, F., Canedo Marroquin, G. & González-Arriagada, W.

  National Agency for Research and Development (ANID)

  15/06/23 → 15/06/25

  Project: Research

• Project Number: 1230875:  REVEALING THE CONTRIBUTION OF MELANOMA-DERIVED CIRCULATING CELL-FREE MITOCHONDRIA IN THE FORMATION OF PREMETASTATIC NICHE IN LYMPH NODES AND THEIR IMPACT IN THE EARLY DEVELOPMENT OF METASTASIS

  Alcayaga-Miranda, F., Khoury, M., Pino-Lagos, K. & Hidalgo, Y.

  National Agency for Research and Development (ANID)

  1/04/23 → 31/03/27

  Project: Research

• Project Number 22I10126: Japi: Cognitive, Emotional and Social Stimulation for Preschool Children

  Gaete Olivares, J. E., Rojas-Barahona, C. A., Matus Correa, P. I. & Araya, R.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  17/10/22 → 17/10/24

  Project: Research

• Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT)

  Khoury, M., Alcayaga-Miranda, F., Cuenca, J., Acevedo, J. P., Figueroa, F., Luz Crawford, P. A., Wyneken, Ú., Illanes, S., Batiz, L. F., Busso, D., J. Monteiro, L., Nardocci, G., Enrione, J. I., Espinoza, F., Valenzuela Bravo, M. T. & Prieto, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/21 → 31/10/26

  Project: Research

• INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL

  Cuenca, J., Alcayaga-Miranda, F., Khoury, M., Hidalgo, Y. & Kurte, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• Impact of Horizontal artificial Transfer of Mitochondria on umbilical cord blood transplantation and its clinical relevance in Graft versus Host Disease

  Khoury, M. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/21 → 29/02/24

  Project: Research

• Franco-Chilean initiative for Intra-Mitochondrial microRNAs as new mediators of mesenchymal stem cells immunoregulatory functions

  Luz Crawford, P. A.

  1/03/21 → 28/02/25

  Project: Research

• Metabolic reprograming of effector CD4+T cells by mitochondrial mediated-signalling in oral cancer and its effect upon T helper and T-dependent B cell responses

  Nova, E. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/21 → 29/02/24

  Project: Research

• Immunoregulatory and anti-rheumatoid arthritis activities of small extracellular vesicles-shuttled bioactive microRNA derived from glycolytic mesenchymal stem cells

  Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/21 → 29/02/24

  Project: Research

• The pathogenic vicious cycle between periodontitis and gestational diabetes mellitus: communication via bacterial translocation and extracellular vesicles

  Chaparro, A. & Busso, D.

  1/03/21 → 29/02/24

  Project: Research

• Prenatal stress: Maternal astrocyte-derived extracellular vesicles as a novel stress-transfer mechanism contributing to adverse offspring neurodevelopment

  Batiz, L. F., Nardocci, G., Wyneken, Ú., Illanes, S., J. Monteiro, L. & Caradeux, J.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/21 → 1/01/25

  Project: Research

• Brain astrocyte-derived extracellular vesicles promote protective Treg induction in the GALT and restore gut tolerance in stressed rats

  Wyneken, Ú. & Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/20 → 31/03/24

  Project: Research

• Mitochondrial transfer within the osteoarthritic joint: restoration of the dysfunctional stress-response and metabolic pathway in cartilage in-vitro and in an animal model of disease

  Figueroa, F.

  1/04/20 → 31/03/24

  Project: Research

• Millennium Institute on Immunology and Immunotherapy (IMII)

  Kalergis, A. M. & Luz Crawford, P. A.

  1/09/11 → 1/09/31

  Project: Research

  • Allergy and Immunology 100%
  • Immunotherapy 41%
  • Endocrine System Diseases 31%
  • Autoimmunity 22%
  • Vaccines 17%
• Finished

  Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis

  Luz Crawford, P. A., Alcayaga-Miranda, F., Elizondo-Vega, R. J., Espinoza, F. & Matas, J.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/21 → 30/11/23

  Project: Research

• Generación de un extracto de un alimento andino con propiedades antidiabéticas

  Busso, D., Enrione, J. I. & Illanes, S.

  1/08/20 → 30/11/20

  Project: Research

• Mirando al futuro: Efectos del estrés prenatal y perinatal asociado a la pandemia COVID-19 en el neurodesarrollo de niñas y niños de Chile

  Batiz, L. F., Illanes, S., J. Monteiro, L., Tenorio, M., Avaria, M. D. L. A., Nardocci, G., Nuñez, M. I. & Peñailillo, R.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  6/07/20 → 1/01/22

  Project: Research

• Role of mesenchymal stem cells in implantation and their contribution to the decidualization disorders present in preeclampsia

  Illanes, S., Pino-Lagos, K., J. Monteiro, L. & Acuña, S.

  1/04/20 → 31/03/23

  Project: Research

• Lipophilic statins inhibit the exosome-mediated and obesity-induced cancer progression: the relevance of reestablishing natural killer cell immune surveillance to delay recurrence and improve future therapeutic outcomes in high-grade serous ovarian cancer

  Cuello, M. & Busso, D.

  1/03/20 → 28/02/23

  Project: Research

• Mitochondrial transfer from mesenchymal stem cells for osteoarthritis treatment

  Figueroa, F. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/20 → 28/02/23

  Project: Research

• Validación de algoritmo multiparamétrico para la predicción temprana de Diabetes Gestacional mediante marcadores plasmáticos maternos

  Illanes, S., J. Monteiro, L., Correa, P. & Monckeberg, M.

  1/01/20 → 1/01/23

  Project: Research

• Estudio de Carga de Enfermedad Atribuible al Actual Nivel de Exposición a Yodo y Ácido Fólico en Chile: Identificación de Niveles Óptimos de Fortificación Nacional y Recomendaciones para una Nueva Política Integrada de Micronutrientes

  Mosso, L. & Busso, D.

  1/10/19 → 31/05/22

  Project: Research

• "ALERT-NeurodEV”: Early detection of prenatal stress-induced neurodevelopmental changes by umbilical cord blood biomarkers

  Batiz, L. F. & Illanes, S.

  Universidad de los Andes Chile

  1/06/19 → 30/09/19

  Project: Research

• Investigating the anti-angiogenic effect of exosome-mediated delivery of functionally active miRNA-149-3p,145-5p and 6131 to tumor tissue

  Alcayaga-Miranda, F. & Cuenca, J.

  1/04/19 → 15/04/23

  Project: Research

• Regulation of mesenchymal stem cell metabolic status to increase their immunosuppresive potential

  Luz Crawford, P. A.

  1/04/19 → 31/03/21

  Project: Research

• Alfa-SNAP regula el balance entre autorenovación/proliferación y diferenciación de células madre neurales, modulando la actividad AMPK y la homeostasis mitocondrial

  Henzi, R. & Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/19 → 1/01/22

  Project: Research

• Use of protein biomarkers in plasma-derived extracellular vesicles to improve the diagnosis of bipolar disorder

  Wyneken, Ú., Batiz, L. F. & Prieto, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/19 → 1/01/21

  Project: Research

• Regulation of mesenchymal stem cells metabolic status to improve their therapeutic potential for arthritis

  Luz Crawford, P. A.

  1/01/19 → 31/12/20

  Project: Research

• The role of FOXM1 in early preeclampsia-related events

  J. Monteiro, L.

  1/11/18 → 14/11/22

  Project: Research

• Effect of genetic variants in calcium channel genes on cardiac function in bipolar disorder

  Batiz, L. F. & Prieto, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/18 → 15/04/22

  Project: Research

• Maternal brain-to-fetal brain communication under stress conditions: role of astrocyte derived-extracellular vesicles

  Batiz, L. F., Illanes, S. & Wyneken, Ú.

  Wayne State University

  1/01/18 → 1/01/20

  Project: Research

• Desarrollo y validación de un producto celular alogénico derivado de células madre estromales para su uso en síndrome de distrés respiratorio agudo

  Cuenca, J. & Alcayaga-Miranda, F.

  23/06/17 → 22/06/19

  Project: Research

• Functional impact of MSC mitochondrial transfer to T lymphocytes and its clinical relevance in a Graft versus Host Disease

  Khoury, M. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/17 → 15/04/21

  Project: Research

• Tecnologías de Imágenes por Resonancia Magnética para enfermedades asociadas a la vejez: cerebro, corazón y vasos

  Irarrázaval, P. & Busso, D.

  1/03/15 → 28/02/18

  Project: Research

• Desarrollo de una plataforma de análisis de interacciones moleculares para el fortalecimiento de la investigación en ciencias biomédicas y biotecnológicas en la UACh

  Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/15 → 1/01/16

  Project: Research

• Center for Interdisciplinary Studies on the Nervous System (CISNe) // Centro Interdisciplinario de estudios del Sistema Nervioso (CISNe)

  Batiz, L. F.

  Universidad Austral de Chile

  1/01/15 → 1/01/18

  Project: Research

• Cholesterol is bad for eggs as much as eggs are bad for cholesterol

  Busso, D.

  1/03/14 → 28/02/15

  Project: Research

• Impact of high density lipoprotein metabolism in mouse oocyte and embryo physiology: underlying mechanisms, pathological implications and potential interventions

  Busso, D.

  1/03/14 → 28/02/17

  Project: Research

• Canonical and non-canonical roles of alpha-SNAP in the pathogenesis of neurodevelopmental disorders: focur on modulation of autophagy and AMPK signaling

  Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/14 → 1/01/18

  Project: Research

• Predicción de Diabetes Gestacional durante el primer trimestre de embarazo mediante modelo multiparamétrico

  Illanes, S. & Correa, P.

  1/12/13 → 1/12/15

  Project: Research

• The role of the aromatase pathway in 2-methoxyestradiol synthesis in the pathogenesis of preeclampsia

  J. Monteiro, L. & Illanes, S.

  2/11/13 → 30/11/17

  Project: Research

• MIRNAS IN THE PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE). PROFILE OF EXPRESSION IN HUMAN DISEASE AND ASSESSMENT OF FUNCTIONAL EFFECTS IN A HUMANIZED MOUSE MODEL OF SLE

  Khoury, M. & Cuenca, J.

  1/04/13 → 31/03/16

  Project: Research

• Investigando las propiedades inmunomodulatorias de una nueva población stem cell de fluido menstrual recientemente caracterizada y exploración de su aplicación potencial en enfermedades inflamatorias

  Khoury, M., Cuenca, J. & Alcayaga-Miranda, F.

  13/12/12 → 15/12/14

  Project: Research

• Estudio de Biomarcadores de daño renal en niños con Diabetes Mellitus tipo 1

  Ugarte, M. F. & Irarrazabal Muñoz, C. E.

  10/12/12 → 10/12/14

  Project: Research

• Estudio de migración y funcionalidad de subpoblaciones de células madre mesenquimales y desarrollo de dispositivos de migración como nueva herramienta de clasificación y selección de subpoblaciones

  Acevedo, J. P.

  22/10/12 → 22/10/13

  Project: Research

• Unrelenting Macrosomia Despite Optimal Glycemic Control in Gestational Diabetes Mellitus: is an Excessive Rise of Maternal Serum Lipids the Link Between Pre-pregnancy Overweight and Excessive Fetal Growth?

  Olmos, P. & Busso, D.

  1/03/12 → 28/02/15

  Project: Research

• Role of Good Cholesterol HDL in Female Fertility

  Busso, D.

  1/03/12 → 28/02/13

  Project: Research

• Southern Center for Research into Nervous System Diseases - CISNe (Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso (CISNe)).

  Batiz, L. F.

  Universidad Austral de Chile

  1/01/12 → 1/01/14

  Project: Research

• Chile potencia Biotecnológica Búsqueda caracterización valorización y comercialización de bioproductos de especies marinas

  Batiz, L. F.

  Corporación de Fomento de la Producción CORFO

  1/01/12 → 1/01/13

  Project: Research

• Etiopatogenia de la hidrocefalia y otros trastornos del desarrollo cerebral: rol de alfa-SNAP en la sobrevida/apoptosis de las células de la zona ventricular

  Velásquez, Z. D. & Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/12 → 1/01/15

  Project: Research