Medicina

Projects

Projects per year 1999 2012 2019 2020 2021 2023 2031

• 2 Not started
• 22 Active
• 54 Finished

Projects per year

Search results

• Active

  FONDECYT REGULAR - 1241103: DECIPHERING THE ROLE OF MITOCHONDRIAL TRANSFER IN THE PATHOPHYSIOLOGY OF PREECLAMPSIA

  Illanes, S., J. Monteiro, L., Nardocci, G. & Acuña, S.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/24 → 31/03/28

  Project: Research

• FONDECYT REGULAR - 1240604: Brain astrocyte-derived extracellular vesicles orchestrate macrophage and microglia polarization under stress conditions through miRNA-dependent regulation of macrophage immunometabolism regulator (MACIR)

  Wyneken, Ú. (Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Hidalgo, Y. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/24 → 31/03/28

  Project: Research

• FONDEF IDEA I+D 2023 - 23I10325: Desarrollo de un producto alogénico basado en un hidrogel bioactivo con nanovesículas extracelulares y su validación como tratamiento endodóntico regenerativo

  Cuenca, J., Brizuela Cordero, C., Khoury, M., Alcayaga-Miranda, F., Canedo Marroquin, G. & González-Arriagada, W.

  National Agency for Research and Development (ANID)

  15/06/23 → 15/06/25

  Project: Research

• FONDECYT POSTDOCTORADO - 3230322: LA EXPRESIÓN DE HSP70 EN LA MEMBRANA DE VESÍCULAS EXTRACELULARES PREVIENEN EL DAÑO RENAL INDUCIDO POR ISQUEMIA/REPERFUSIÓN EN RATÓN.

  Irarrazabal Muñoz, C. E. & Soto, P.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  15/04/23 → 14/04/26

  Project: Research

• FONDECYT POSTDOCTORADO - 3230447: TRASPLANTE DE MITOCONDRIAS RESISTENTES A LA HIPOXIA: UNA PROMETEDORA TERAPIA CONTRA LA HIPERTENSIÓN PULMONAR HIPÓXICA

  Cuenca, J. & Castillo, S.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  15/04/23 → 14/04/26

  Project: Research

• FONDECYT POSTDOCTORADO - 3230201: ROLE OF BASIGIN ON TROPHOBLAST INVASION REGULATED THROUGH EXTRACELULLAR VESICLES RELEASED FROM ENDOMETRIAL MESENCHYMAL STEM CELLS

  Illanes, S. & Peñailillo, R.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  15/04/23 → 14/04/26

  Project: Research

• FONDECYT REGULAR - 1230932: THE POTENTIAL ROLE OF MENSTRUAL MESENCHYMAL STEM CELLS IN THE ETIOPATHOLOGY OF ENDOMETRIOSIS AND ITS ASSOCIATION WITH IMPAIRED ENDOMETRIUM RECEPTIVITY

  J. Monteiro, L., Donoso, M. B., Vega-Letter, A. M., Illanes, S. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/23 → 31/03/27

  Project: Research

• FONDECYT REGULAR - 1230875:  REVEALING THE CONTRIBUTION OF MELANOMA-DERIVED CIRCULATING CELL-FREE MITOCHONDRIA IN THE FORMATION OF PREMETASTATIC NICHE IN LYMPH NODES AND THEIR IMPACT IN THE EARLY DEVELOPMENT OF METASTASIS

  Alcayaga-Miranda, F. (Principal Investigator), Khoury, M. (Co-Investigator), Pino-Lagos, K. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & González-Arriagada, W. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/23 → 31/03/27

  Project: Research

• Project Number 22I10126: Japi: Cognitive, Emotional and Social Stimulation for Preschool Children

  Gaete Olivares, J. E. (Principal Investigator), Rojas-Barahona, C. A. (Co-Investigator), Matus Correa, P. I. (Co-Investigator) & Araya, R. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  17/10/22 → 17/10/24

  Project: Research

• FONDECYT POSTDOCTORADO - 3220204: TRANSFERENCIA MITOCONDRIAL DESDE CÉLULAS MADRE MESENQUIMALES COMO UNA NUEVA ALTERNATIVA TERAPÉUTICA PARA DESÓRDENES DEL NEURODESARROLLO: RELEVANCIA EN EL RESCATE METABÓLICO Y FUNCIONAL DE CÉLULAS MADRE NEURALES

  Luz Crawford, P. A. & Bustamante, F. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  15/04/22 → 14/04/25

  Project: Research

• FONDECYT REGULAR - 1221376: UNCOVERING MECHANISMS CONTRIBUTING TO EXCENCEPHALY AND ITS PREVENTION BY MATERNAL VITAMIN E SUPPLEMENTATION IN HDL RECEPTOR SR-B1 KO MOUSE EMBRYOS

  Busso, D. (Principal Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/22 → 31/03/26

  Project: Research

• FONDECYT INICIACIÓN - 11220601: EXPLORING THE CONTRIBUTION OF ASTROCYTE-DERIVED EXTRACELLULAR VESICLES TO CONTROL AXONAL PROTEIN SYNTHESIS BY MICRORNA TRANSFER

  Luarte Navarro, A. E.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  15/03/22 → 14/03/25

  Project: Research

• Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT)

  Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. (Associate Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/21 → 31/10/26

  Project: Research

• FONDECYT REGULAR - 1211353: INVESTIGATING THE IMMUNOREGULATORY AND ANTI-RHEUMATOID ARTHRITIS ACTIVITIES OF SMALL EXTRACELLULAR VESICLES-SHUTTLED BIOACTIVE MICRORNA DERIVED FROM GLYCOLYTIC MESENCHYMAL STEM CELL

  Luz Crawford, P. A., Khoury, M., Alcayaga-Miranda, F., Elizondo-Vega, R., Altamirano, C. & Nova-Lamperti, E.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• FONDECYT REGULAR - 1211749: IMPACT OF HORIZONTAL ARTIFICIAL TRANSFER OF MITOCHONDRIA ON UMBILICAL CORD BLOOD TRANSPLANTATION AND ITS CLINICAL RELEVANCE IN GRAFT VERSUS HOST DISEASE.

  Khoury, M., Luz Crawford, P. A., Court, A. C. & Figueroa, F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL

  Cuenca, J., Alcayaga-Miranda, F., Khoury, M., Hidalgo, Y. & Kurte, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• FONDECYT REGULAR - 1211376: INVESTIGATING THE EFFECT OF MAVS-ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRAL-INDUCED ACUTE LUNG INJURY MODEL.

  Cuenca, J., Alcayaga-Miranda, F., Khoury, M., Hidalgo, Y. & Kurte, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• FONDECYT REGULAR - 1210654: SMALL EXTRACELLULAR VESICLES OBTAINED FROM NEUROPILIN-1+ T REGULATORY CELLS AS A NOVEL TOOL FOR THE INDUCTION OF TRANSPLANTATION TOLERANCE

  Pino-Lagos, K. (Principal Investigator) & Wyneken, Ú. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• FONDECYT REGULAR - 1211384: PRENATAL STRESS: MATERNAL ASTROCYTE-DERIVED EXTRACELLULAR VESICLES AS A NOVEL STRESS-TRANSFER MECHANISM CONTRIBUTING TO ADVERSE OFFSPRING NEURODEVELOPMENT

  Batiz, L. F., Nardocci, G., Wyneken, Ú., Illanes, S., J. Monteiro, L. & Caradeux, J.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• FONDECYT REGULAR - 1211471: THE PATHOGENIC VICIOUS CYCLE BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES MELLITUS: COMMUNICATION VIA BACTERIAL TRANSLOCATION AND EXTRACELLULAR VESICLES

  Chaparro, A. (Principal Investigator), Busso, D. (Co-Investigator), Illanes, S. (Co-Investigator), Ramirez Lobos, V. (Co-Investigator), Hernández Ríos, E. (Co-Investigator) & Hoare, A. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• Franco-Chilean initiative for Intra-Mitochondrial microRNAs as new mediators of mesenchymal stem cells immunoregulatory functions

  Luz Crawford, P. A.

  1/03/21 → 28/02/25

  Project: Research

• Millennium Institute on Immunology and Immunotherapy (IMII)

  Kalergis, A. M. (Principal Investigator) & Luz Crawford, P. A. (Co-Investigator)

  1/09/11 → 1/09/31

  Project: Research

  • Immunology 100%
  • Immunotherapy 100%
  • Antihormone Therapy 50%
  • Cellular Immunology 50%
  • Young Scientists 50%
• Not started

  FONDECYT POSTDOCTORADO - 3240135: Parches cardiacos multifuncionales basados en biomateriales electroconductores cargados con células madre mesenquimales

  Acevedo, J. P. & Olate, F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  Project: Research

• FONDECYT POSTDOCTORADO - 3240476: Characterization and validation of early biomarkers of maternal supraphysiological hypercholesterolemia in maternal plasma from the first trimester of pregnancy

  Illanes, S. & Cantin, C.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  Project: Research

• Finished

  Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis

  Luz Crawford, P. A., Alcayaga-Miranda, F., Elizondo-Vega, R. J., Espinoza, F. & Matas, J.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/21 → 30/11/23

  Project: Research

• Metabolic reprograming of effector CD4+T cells by mitochondrial mediated-signalling in oral cancer and its effect upon T helper and T-dependent B cell responses

  Nova, E. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/21 → 29/02/24

  Project: Research

• Immunoregulatory and anti-rheumatoid arthritis activities of small extracellular vesicles-shuttled bioactive microRNA derived from glycolytic mesenchymal stem cells

  Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/21 → 29/02/24

  Project: Research

• Generación de un extracto de un alimento andino con propiedades antidiabéticas

  Busso, D. (Principal Investigator), Enrione, J. I. (Principal Investigator) & Illanes, S. (Principal Investigator)

  1/08/20 → 30/11/20

  Project: Research

• Mirando al futuro: Efectos del estrés prenatal y perinatal asociado a la pandemia COVID-19 en el neurodesarrollo de niñas y niños de Chile

  Batiz, L. F., Illanes, S., J. Monteiro, L., Tenorio, M., Avaria, M. D. L. A., Nardocci, G., Nuñez, M. I. & Peñailillo, R.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  6/07/20 → 1/01/22

  Project: Research

• FONDECYT REGULAR - 1200693: Brain astrocyte-derived extracellular vesicles promote protective Treg induction in the GALT and restore gut tolerance in stressed rats

  Wyneken, Ú. (Principal Investigator), Batiz, L. F. (Co-Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Batiz, L. F. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/20 → 31/03/24

  Project: Research

• FONDECYT REGULAR - 1201420: Mitochondrial transfer within the osteoarthritic joint: restoration of the dysfunctional stress-response and metabolic pathway in cartilage in-vitro and in an animal model of disease

  Figueroa, F., Khoury, M., Luz Crawford, P. A. & Court, A. C.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/20 → 31/03/24

  Project: Research

• FONDECYT REGULAR - 1201851: Role of mesenchymal stem cells in implantation and their contribution to the decidualization disorders present in preeclampsia

  Illanes, S. (Principal Investigator), Pino-Lagos, K. (Co-Investigator), J. Monteiro, L. (Co-Investigator) & Acuña, S. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/20 → 31/03/23

  Project: Research

• Mitochondrial transfer from mesenchymal stem cells for osteoarthritis treatment

  Figueroa, F. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/20 → 28/02/23

  Project: Research

• Lipophilic statins inhibit the exosome-mediated and obesity-induced cancer progression: the relevance of reestablishing natural killer cell immune surveillance to delay recurrence and improve future therapeutic outcomes in high-grade serous ovarian cancer

  Cuello, M. (Principal Investigator) & Busso, D. (Co-Investigator)

  1/03/20 → 28/02/23

  Project: Research

• Validación de algoritmo multiparamétrico para la predicción temprana de Diabetes Gestacional mediante marcadores plasmáticos maternos

  Illanes, S., J. Monteiro, L., Correa, P. & Monckeberg, M.

  1/01/20 → 1/01/23

  Project: Research

• Estudio de Carga de Enfermedad Atribuible al Actual Nivel de Exposición a Yodo y Ácido Fólico en Chile: Identificación de Niveles Óptimos de Fortificación Nacional y Recomendaciones para una Nueva Política Integrada de Micronutrientes

  Mosso, L. (Principal Investigator) & Busso, D. (Co-Investigator)

  1/10/19 → 31/05/22

  Project: Research

• "ALERT-NeurodEV”: Early detection of prenatal stress-induced neurodevelopmental changes by umbilical cord blood biomarkers

  Batiz, L. F. & Illanes, S.

  Universidad de los Andes Chile

  1/06/19 → 30/09/19

  Project: Research

• Regulation of mesenchymal stem cell metabolic status to increase their immunosuppresive potential

  Luz Crawford, P. A.

  1/04/19 → 31/03/21

  Project: Research

• FONDECYT REGULAR - 1190411: Investigating the anti-angiogenic effect of exosome-mediated delivery of functionally active miRNA-149-3p,145-5p and 6131 to tumor tissue

  Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Co-Investigator), Khoury, M. (Co-Investigator) & Pino-Lagos, K. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/19 → 15/04/23

  Project: Research

• FONDECYT POSTDOCTORADO - 3190646: ALFA-SNAP REGULA EL BALANCE ENTRE AUTORENOVACIÓN/PROLIFERACIÓN Y DIFERENCIACIÓN DE CÉLULAS MADRE NEURALES, MODULANDO LA ACTIVIDAD AMPK Y LA HOMEOSTASIS MITOCONDRIAL

  Henzi, R. & Batiz, L. F.

  Consejo Nacional para Investigaciones Científicas y Tecnológicas

  15/03/19 → 14/03/22

  Project: Research

• Use of protein biomarkers in plasma-derived extracellular vesicles to improve the diagnosis of bipolar disorder

  Wyneken, Ú., Batiz, L. F. & Prieto, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/19 → 1/01/21

  Project: Research

• Regulation of mesenchymal stem cells metabolic status to improve their therapeutic potential for arthritis

  Luz Crawford, P. A.

  1/01/19 → 31/12/20

  Project: Research

• FONDECYT INICIACIÓN - 11181249: THE ROLE OF FOXM1 IN EARLY PREECLAMPSIA-RELATED EVENTS

  J. Monteiro, L.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/18 → 16/05/23

  Project: Research

• FONDECYT REGULAR - 1181365: EFFECT OF GENETIC VARIANTS IN CALCIUM CHANNEL GENES ON CARDIAC FUNCTION IN BIPOLAR DISORDER

  Batiz, L. F., Prieto, M., De León, A., Veas, N., Cavada, G. & Fullerton, C.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/18 → 31/03/23

  Project: Research

• Maternal brain-to-fetal brain communication under stress conditions: role of astrocyte derived-extracellular vesicles

  Batiz, L. F., Illanes, S. & Wyneken, Ú.

  Wayne State University

  1/01/18 → 1/01/20

  Project: Research

• Desarrollo y validación de un producto celular alogénico derivado de células madre estromales para su uso en síndrome de distrés respiratorio agudo

  Cuenca, J. & Alcayaga-Miranda, F.

  23/06/17 → 22/06/19

  Project: Research

• FONDECYT REGULAR - 1170852: Functional impact of MSC mitochondrial transfer to T lymphocytes and its clinical relevance in a Graft versus Host Disease

  Khoury, M. (Principal Investigator), Luz Crawford, P. A. (Co-Investigator), Pino-Lagos, K. (Co-Investigator) & Figueroa, F. (Co-Investigator)

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/17 → 31/03/21

  Project: Research

• FONDECYT INICIACIÓN - 11160929: Study of the metabolic plasticity of mesenchymal stem cells and its role in their immunomodulatory effects on pathogenic T cells: Toward an optimization of their therapeutic potential for autoimmune diseases.

  Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/16 → 31/10/19

  Project: Research

• Tecnologías de Imágenes por Resonancia Magnética para enfermedades asociadas a la vejez: cerebro, corazón y vasos

  Irarrázaval, P. (Principal Investigator) & Busso, D. (Co-Investigator)

  1/03/15 → 28/02/18

  Project: Research

• Center for Interdisciplinary Studies on the Nervous System (CISNe) // Centro Interdisciplinario de estudios del Sistema Nervioso (CISNe)

  Batiz, L. F.

  Universidad Austral de Chile

  1/01/15 → 1/01/18

  Project: Research