Projects per year
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Collaborations and top research areas from the last five years
Profiles
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Úrsula Wyneken, PhD
- Claustro Doctorado en Biomedicina
- Centro de Investigación e Innovación Biomédica
- Doctorado en Biomedicina
- Facultad de Medicina
- Grupo de Vesículas Extracelulares en Patologías del Sistema Nervioso
- Medicina
- Programa de Neurociencias
Person: Researcher, Academic, Full graduate faculty members
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FONDECYT REGULAR - 1240604: Brain astrocyte-derived extracellular vesicles orchestrate macrophage and microglia polarization under stress conditions through miRNA-dependent regulation of macrophage immunometabolism regulator (MACIR)
Wyneken, Ú. (Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Hidalgo, Y. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/24 → 31/03/28
Project: Research
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IMPACT: CENTER OF INTERVENTIONAL MEDICINE FOR PRECISION AND ADVANCED CELLULAR THERAPY
Khoury, M. (Director), Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Principal Investigator), Acevedo, J. P. (Principal Investigator), Figueroa, F. (Principal Investigator), Luz Crawford, P. A. (Principal Investigator), Wyneken, Ú. (Principal Investigator), Illanes, S. (Principal Investigator), Batiz, L. F. (Associate Investigator), Busso, D. (Associate Investigator), J. Monteiro, L. (Associate Investigator), Nardocci, G. (Associate Investigator), Enrione, J. I. (Associate Investigator), Espinoza, F. (Associate Investigator), Valenzuela Bravo, M. T. (Associate Investigator) & Prieto, M. (Associate Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/11/21 → 31/10/26
Project: Research
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FONDECYT REGULAR - 1210654: SMALL EXTRACELLULAR VESICLES OBTAINED FROM NEUROPILIN-1+ T REGULATORY CELLS AS A NOVEL TOOL FOR THE INDUCTION OF TRANSPLANTATION TOLERANCE
Pino-Lagos, K. (Principal Investigator) & Wyneken, Ú. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo (ANID)
1/04/21 → 31/03/25
Project: Research
Research output
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Bulk serum extracellular vesicles from stressed mice show a distinct proteome and induce behavioral and molecular changes in naive mice
Monteleone, M. C., Billi, S. C., Abarzúa-Catalán, L., Henzi, R., Fernández, E. M., Kaehne, T., Wyneken, U. & Brocco, M. A., 1 Aug 2024, In: PLoS ONE. 19, 8, e0308976.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial: Medicinal drugs, the effect on memories and beyond
Moreira-Rodrigues, M., Ampuero, E. & Wyneken, U., 2024, In: Frontiers in Pharmacology. 15, 1471049.Research output: Contribution to journal › Editorial
Open Access -
Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice
Acuña-Catalán, D., Shah, S., Wehrfritz, C., Nomura, M., Acevedo, A., Olmos, C., Quiroz, G., Huerta, H., Bons, J., Ampuero, E., Wyneken, U., Sanhueza, M., Arancibia, F., Contreras, D., Cárdenas, J. C., Morales, B., Schilling, B., Newman, J. C. & González-Billault, C., 18 Jun 2024, In: Cell Reports Medicine. 5, 6, 101593.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Activities
- 3 Oral presentation
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The M105I mutation of alpha-SNAP leads to increased levels of pAMPK affecting the mitochondrial homeostasis and the balance between proliferation and differentiation of neural stem/progenitor cells
Henzi, R. (Keynote speaker), Bustamante, F. A. (Speaker), Méndez, M. (Speaker), Wyneken, Ú. (Speaker) & Batiz, L. F. (Speaker)
2021Activity: Talk or presentation › Oral presentation
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SUMOylation determines the protein cargo of astrocyte-derived small extracellular vesicles
Méndez, M. (Keynote speaker), Fernández, A. (Speaker), Batiz, L. F. (Speaker), Henzi, R. (Speaker), Rojas-Fernández, A. (Speaker) & Wyneken, Ú. (Speaker)
2019Activity: Talk or presentation › Oral presentation
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Maternal brain-to-fetal brain communication mediated by small extracellular vesicles: Possible role in prenatal stress
Abarzua-Catalan, L. (Speaker), Henzi, R. (Speaker), Wyneken, Ú. (Speaker), Illanes, S. (Speaker) & Batiz, L. F. (Keynote speaker)
2019Activity: Talk or presentation › Oral presentation