Grupo de Investigación en Microbioma Humano

Research output

Research output per year 2010 2013 2020 2021

• 366 Citations
• 7 h-Index
• 21 Article
• 1 Other contribution

Research output per year

Research output per year

Search results

• 2021

  Low-Level Laser Irradiation Promotes Proliferation and Differentiation on Apical Papilla Stem Cells

  Gutiérrez, D., Rouabhia, M., Ortiz, J., Gaviria, D., Alfonso, C., Muñoz, A. & Inostroza, C., 2021, In: Journal of Lasers in Medical Sciences. 12, 1, e75.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dental Papilla 100%
  • Low-Level Light Therapy 60%
  • Lasers 55%
  • Stem Cells 50%
  • Vascular Endothelial Growth Factor A 14%
• 2020

  Allogeneic Cellular Therapy in a Mature Tooth with Apical Periodontitis and Accidental Root Perforation: A Case Report

  Cordero, C. B., Santander, G. M., González, D. U., Quezada, A., Silva, C. I., Vásquez, C., Jara, R., Jara, D. & Khoury, M., Dec 2020, In: Journal of Endodontics. 46, 12, p. 1920-1927.e1

  Research output: Contribution to journal › Article › peer-review

  • Periapical Periodontitis 100%
  • Tooth 50%
  • Composite Resins 32%
  • Umbilical Cord 31%
  • Endodontics 31%
  3 Scopus citations

• Dental Forensic Kit (DFK®) and Quick Extract™ FFPE DNA extraction kit, a new workflow for obtaining dental DNA for human genetic identity

  Inostroza, C., Carrasco, P., Godoy, M., Gatti, G. & Paulino, B., Jul 2020, In: Journal of Forensic and Legal Medicine. 73, 101992.

  Research output: Contribution to journal › Article › peer-review

  • Human Genetics 100%
  • Workflow 90%
  • Pedigree 89%
  • workflow 89%
  • Formaldehyde 76%
  2 Scopus citations

• Inflammatory biomarkers in dentinal fluid as an approach to molecular diagnostics in pulpitis.

  Brizuela, C., Meza, G., Mercadé, M., Inostroza, C., Chaparro, A., Bravo, I., Briceño, C., Hernández, M., Giner, L., Ramírez, V. & Chaparro, A., 1 Sep 2020, In: International Endodontic Journal. 53, 9, p. 1181-1191 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dentinal Fluid 100%
  • Pulpitis 80%
  • Molecular Pathology 61%
  • Biomarkers 34%
  • Acids 16%
  7 Scopus citations

• Mesenchymal Stem Cells Derived from Human Inflamed Dental Pulp Exhibit Impaired Immunomodulatory Capacity In Vitro

  Inostroza, C., Vega-Letter, A. M., Brizuela, C., Castrillón, L., Saint Jean, N., Duran, C. M. & Carrión, F., Aug 2020, In: Journal of Endodontics. 46, 8, p. 1091-1098.e2

  Research output: Contribution to journal › Article › peer-review

  • Pulpitis 100%
  • Dental Pulp 84%
  • Mesenchymal Stem Cells 59%
  • Tooth 37%
  • In Vitro Techniques 29%
  2 Scopus citations

• Optimizing DNA recovery and forensic typing of degraded blood and dental remains using a specialized extraction method, comprehensive qPCR sample characterization, and massively parallel sequencing.

  Carrasco, P., Inostroza, C., Didier, M., Godoy, M., Holt, C. L., Tabak, J. & Loftus, A., 1 Jan 2020, In: International Journal of Legal Medicine. 134, 1, p. 79-91 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Blood Grouping and Crossmatching 100%
  • High-Throughput Nucleotide Sequencing 64%
  • Tooth 48%
  • DNA 37%
  • Microsatellite Repeats 28%
  10 Scopus citations
• 2019

  Distribución espacial en el canal radicular del coágulo y de la membrana obtenida de fibrina rica en plaquetas

  Brizuela Cordero, C., Inostroza, C., Pérez, V. & Saint Jean, N., 10 Oct 2019, In: Canal Abierto. p. 4-9 6 p.

  Research output: Contribution to journal › Article › peer-review

• Personalized Cell Therapy for Pulpitis Using Autologous Dental Pulp Stem Cells and Leukocyte Platelet-rich Fibrin: A Case Report

  Meza, G., Urrejola, D., Saint Jean, N., Inostroza, C., López, V., Khoury, M. & Brizuela, C., Feb 2019, In: Journal of Endodontics. 45, 2, p. 144-149 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Platelet-Rich Fibrin 100%
  • Pulpitis 99%
  • Dental Pulp 83%
  • Cell- and Tissue-Based Therapy 62%
  • Stem Cells 48%
  28 Scopus citations
• 2017

  Direct Pulp Capping with Calcium Hydroxide, Mineral Trioxide Aggregate, and Biodentine in Permanent Young Teeth with Caries: A Randomized Clinical Trial

  Brizuela, C., Ormeño, A., Cabrera, C., Cabezas, R., Silva, C. I., Ramírez, V. & Mercade, M., Nov 2017, In: Journal of Endodontics. 43, 11, p. 1776-1780 5 p.

  Research output: Contribution to journal › Article › peer-review

  • tricalcium silicate 100%
  • Dental Pulp Capping 96%
  • mineral trioxide aggregate 87%
  • Calcium Hydroxide 84%
  • Tooth 44%
  74 Scopus citations

• Histological transformations of the dental pulp as possible indicator of post mortem interval: a pilot study

  Carrasco, P. A., Brizuela, C. I., Rodriguez, I. A., Muñoz, S., Godoy, M. E. & Inostroza, C., Oct 2017, In: Forensic Science International. 279, p. 251-257 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Dental Pulp 100%
  • death 38%
  • Postmortem Changes 35%
  • Tooth 32%
  • cause of death 29%
  7 Scopus citations
• 2016

  MatrigelBD, un andamiaje biocompatible que estimula la proliferación de celulas troncales mesenquimales derivadas del tejido gingival

  Translated title of the contribution: MatrigelBD, a biocompatible scaffold that improves gingival mesenchymal stem cells proliferationBrizuela, C., SaintJean, N., Garchitorena, N., Rodriguez, I. & Inostroza Silva, C., Jun 2016, In: International Journal of Morphology. 34, 2, p. 692-698 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mesenchymal Stem Cells 100%
  • Cell Proliferation 73%
  • Cell Differentiation 60%
  • Hydrogels 39%
  • Growth 37%

• Placental biomarkers and angiogenic factors in oral fluids of patients with preeclampsia

  Chaparro, A., Gaedechens, D., Ramírez, V., Zuñiga, E., Kusanovic, J. P., Inostroza, C., Varas-Godoy, M., Silva, K., Salomon, C., Rice, G. & Illanes, S. E., 1 May 2016, In: Prenatal Diagnosis. 36, 5, p. 476-482 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiogenesis Inducing Agents 100%
  • Pre-Eclampsia 89%
  • Gingival Crevicular Fluid 88%
  • Biomarkers 58%
  • placental alkaline phosphatase 56%
  18 Scopus citations
• 2015

  Cambios del estado clínico periodontal según consumo sistémico de estatinas

  Rosenberg, D., Andrade, C., Larrea, R. E., Chaparro, A., silva, C., Ramírez, V., Urquidi Bellota, C., Violant, D. & Nart, J., 2015, In: Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral. 8, 2, p. 111-116

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2014

  Biocompatibilidad de células madres mesenquimales de tejido gingival humano en cultivo con un andamiaje de polímero sintético de ácido poliláctico (OPLA)

  Translated title of the contribution: Biocompatibility of mesenchymal stem cells derived from human gingival tissue in culture with a scaffold of a synthetic polymer Open Porosity Polylactic Acid Polymer (OPLA)Brizuela Cordero, C., Saint Jean, N. & Inostroza Silva, C., 2014, In: International Journal of Morphology. 32, 3, p. 767-772 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • poly(lactide) 100%
  • Porosity 99%
  • Mesenchymal Stem Cells 75%
  • Polymers 74%
  • Cell Differentiation 41%
  1 Scopus citations

• Estimación de la edad médico-legal usando dos métodos para la medición de la translucidez dentinaria radicular: análisis comparativo

  Translated title of the contribution: Legal medical age estimation using two methods measuring root dentin translucency: Comparative analysisCarrasco Tapia, P., González Srur, J., Brizuela, C. & Inostroza Silva, C., 2014, In: International Journal of Morphology. 32, 3, p. 956-961 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dentin 100%
  • Age Determination by Teeth 18%
  • Criminology 15%
  • Biological Phenomena 8%
  • Cause of Death 6%
  1 Scopus citations
• 2013

  Aislación y caracterización de células madre mesenquimales provenientes de pulpa y folículo dentario humano

  Translated title of the contribution: Isolation and characterization of mesenchymal stem cells from human dental pulp and follicleBrizuela C., C., Galleguillos G., S., Carrión A., F., Cabrera P., C., Luz C., P. & Inostroza S., C., Jun 2013, In: International Journal of Morphology. 31, 2, p. 739-746 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dental Sac 100%
  • Dental Pulp 80%
  • Mesenchymal Stem Cells 57%
  • Mouth 13%
  • Tooth 11%
  5 Scopus citations

• Expresión de citoquinas Th17 y su correlación con periodontopatógenos y el área periodontal inflamada en pacientes con periodontitis crónica

  Translated title of the contribution: Th17 cytokines expression and its correlation with periodontopathogens and periodontal inflammed surface area (PISA) in patients with chronic periodontitisChaparro, A., Quintero, A. J., Sanz, A., Gaedechens, D., Carrión, F., Silva, C., Herane, A. & Hernandez, M., 2013, In: Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral. 6, 3, p. 109 113 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Increased inflammatory biomarkers in early pregnancy is associated with the development of pre-eclampsia in patients with periodontitis: A case control study

  Chaparro, A., Sanz, A., Quintero, A., Inostroza, C., Ramirez, V., Carrion, F., Figueroa, F., Serra, R. & Illanes, S. E., Jun 2013, In: Journal of Periodontal Research. 48, 3, p. 302-307 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Gingival Crevicular Fluid 100%
  • Periodontitis 91%
  • Pre-Eclampsia 84%
  • Case-Control Studies 67%
  • Biomarkers 54%
  21 Scopus citations

• Porphyromonas gingivalis, Treponema denticola and toll-like receptor 2 are associated with hypertensive disorders in placental tissue: A case-control study

  Chaparro, A., Blanlot, C., Ramírez, V., Sanz, A., Quintero, A., Inostroza, C., Bittner, M., Navarro, M. & Illanes, S. E., Dec 2013, In: Journal of Periodontal Research. 48, 6, p. 802-809 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Treponema denticola 100%
  • Toll-Like Receptor 2 84%
  • Porphyromonas gingivalis 81%
  • Case-Control Studies 53%
  • Logistic Models 34%
  31 Scopus citations
• 2012

  Evaluación de la proliferación de células madres mesenquimales estimuladas con diferentes intensidades de ultrasonido de baja intensidad

  Translated title of the contribution: Evaluation of mesenchymal stem cell proliferation using different low intensity pulsed ultrasound intensitiesBecerra, D., Jaime Díaz, Z., Flavio Carrión, A., Inostroza, C. & Rodrigo Oyonarte, W., Jun 2012, In: International Journal of Morphology. 30, 2, p. 621-626 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ultrasonic Waves 100%
  • Mesenchymal Stem Cells 68%
  • Cell Proliferation 50%
  • In Vitro Techniques 13%
  • Sprague Dawley Rats 12%
  2 Scopus citations
• 2010

  Autologous mesenchymal stem cell treatment increased T regulatory cells with no effect on disease activity in two systemic lupus erythematosus patients

  Carrion, F., Nova, E., Ruiz, C., Diaz, F., Inostroza, C., Rojo, D., MÖnckeberg, G. & Figueroa, F. E., Mar 2010, In: Lupus. 19, 3, p. 317-322 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Regulatory T-Lymphocytes 100%
  • Systemic Lupus Erythematosus 94%
  • Mesenchymal Stem Cells 90%
  • In Vitro Techniques 16%
  • Therapeutics 16%
  154 Scopus citations