Projects per year
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DESAFÍO GLOBAL EN LONGEVIDAD SALUDABLE: CATCH IT EARLY: REVOLUTIONIZING DIFFERENTIAL MILD COGNITIVE IMPAIRMENT DIAGNOSIS WITH CELLULAR SENSORS FOR EARLY DETECTION OF ALZHEIMER’S DISEASE AND NEURODEGENERATION
Wyneken, Ú. (Director) & Luarte Navarro, A. E. (Alternate Director)
1/12/23 → 30/12/24
Project: RESEARCH
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FAI ATP MICARE - INV-ATP MICARE-2023-01: IMPACTO DE UN PROGRAMA DE EDUCACIÓN EN SALUD ORAL DIRIGIDO A CUIDADORES DE PERSONAS MAYORES CON DISTINTOS GRADOS DE DETERIORO COGNITIVO EN EL CONTROL DEL BIOFILM DENTAL
Prieto Damm, D. J. (Principal Investigator) & Chaparro, A. (Co-Investigator)
Universidad de los Andes Chile
1/10/23 → 1/10/24
Project: RESEARCH
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FAI INSCRIPCION CONGRESO - APO-CG-2023-28: INCREASED GINGIVAL CREVICULAR FLUID EXTRACELLULAR VESICLES ARE INVOLVED IN THE CROSSTALK BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES
Mizgier, M. L. (Principal Investigator), Realini, O. (Co-Investigator), Bendek Viera, M. J. (Co-Investigator), Rojas Pérez, C. I. (Co-Investigator), Monje, S. (Co-Investigator), Figari, A. (Co-Investigator), Hernández, M. (Co-Investigator), Ramírez Lobos, V. (Co-Investigator), Illanes, S. (Co-Investigator), Busso, D. (Co-Investigator) & Chaparro, A. (Co-Investigator)
Universidad de los Andes Chile
4/09/23 → 30/12/23
Project: RESEARCH
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FAI ORGANIZACIÓN CONGRESO - APO-OR-2023-03: PERIODONTAL DISEASE AND SYSTEMIC HEALTH: THE PERIO-INFLAMMATION SYMPOSIUM
Chaparro, A. (Principal Investigator)
Universidad de los Andes Chile
1/07/23 → 28/02/24
Project: RESEARCH
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FONDEF IDEA I+D 2023 - 23I10325: Desarrollo de un producto alogénico basado en un hidrogel bioactivo con nanovesículas extracelulares y su validación como tratamiento endodóntico regenerativo
Cuenca, J. (Principal Investigator), Brizuela Cordero, C. I. (Alternate Director), Khoury, M. (Co-Investigator), Alcayaga-Miranda, F. (Co-Investigator), Canedo Marroquin, G. (Co-Investigator) & González-Arriagada, W. A. (Co-Investigator)
National Agency for Research and Development (ANID)
15/06/23 → 15/06/25
Project: RESEARCH
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FONDEF 1RA ETAPA - ID22I10215: PREVENTING HYPOSALIVATION AND SALIVARY GLAND DYSFUNCTION FOLLOWING Γ-IRRADIATION OF THE HEAD AND NECK USING INJECTABLE AND RELEASE-TUNABLE NANO-SIZED DUAL-DRUG DELIVERY SYSTEM: PRE-CLINICAL SAFETY AND EFFICACY VALIDATION; A STEP CLOSER TO THE CLINIC
Haidar, Z. S. (Principal Investigator) & Bravo, C. (Co-Investigator)
14/10/22 → 16/10/24
Project: RESEARCH
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CONTRATOS TECNOLOGICOS - 22CVID-206879: SCREENING ORAL PARA LA PREDICCIÓN TEMPRANA DE DIABETES GESTACIONAL
Chaparro, A. (Principal Investigator), Illanes, S. (Co-Investigator) & Nardocci, G. (Co-Investigator)
1/09/22 → 26/10/24
Project: RESEARCH
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FAIN - 202201: Desarrollo de un algoritmo multiparamétrico para diagnóstico no invasivo de endometriosis
J. Monteiro, L. (Director)
16/08/22 → 16/11/23
Project: RESEARCH
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FAI INSCRIPCION CONGRESO - APO-CG-2022-03: SOCKGEL/PLUG: INJECTABLE NANO-SCALED HYDROGEL PLATFORMS FOR ORAL AND MAXILLOFACIAL INTERVENTIONAL APPLICATION
Haidar, Z. S. (Principal Investigator)
Universidad de los Andes Chile
1/08/22 → 30/09/22
Project: RESEARCH
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FONDECYT POSTDOCTORADO - 3220289: ESTUDIO DE LA ESTRUCTURA INTERFACIAL DE EMULSIONES PICKERING O/W A PARTIR DE NANOCRISTALES DE CELULOSA DE PINO OBTENIDOS POR DIFERENTES PROCESOS DE HIDRÓLISIS.
Díaz Calderón, P. C. (Sponsoring Researcher) & Alarcón, J. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo
15/04/22 → 14/04/25
Project: RESEARCH
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FONDECYT POSTDOCTORADO - 3220204: TRANSFERENCIA MITOCONDRIAL DESDE CÉLULAS MADRE MESENQUIMALES COMO UNA NUEVA ALTERNATIVA TERAPÉUTICA PARA DESÓRDENES DEL NEURODESARROLLO: RELEVANCIA EN EL RESCATE METABÓLICO Y FUNCIONAL DE CÉLULAS MADRE NEURALES
Luz Crawford, P. A. (Sponsoring Researcher) & Bustamante, F. A. (Postdoctoral Researcher)
Agencia Nacional de Investigación y Desarrollo
15/04/22 → 14/04/25
Project: RESEARCH
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FONDECYT REGULAR – 1221099: UNDERSTANDING THE ROLE OF NANOCELLULOSE ON THE SELF-ASSOCIATION AND SELF-ASSEMBLING OF AMYLOSE-AMYLOPECTIN BASED COMPOSITES
Díaz Calderón, P. C. (Principal Investigator) & Quero, F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/22 → 31/03/25
Project: RESEARCH
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FONDEFf IDEA I+D - IT21l0080: Biomanufacturing of Tissue Engineered Vascular Access for Hemodialysis
Acevedo, J. P. (Principal Investigator) & Cuenca, J. (Alternate Director)
3/01/22 → 1/02/24
Project: RESEARCH
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Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis
Luz Crawford, P. A. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Elizondo-Vega, R. J. (Co-Investigator), Espinoza, F. (Co-Investigator) & Matas, J. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/11/21 → 30/11/23
Project: RESEARCH
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NAM - NAM21I0022: VALIDATING A SUTURE- AND DRUG-FREE HYDROGEL AS AN INJECTABLE ORAL DRESSING FOR PAINLESS PROMOTION OF DENTAL EXTRACTION SOCKET HEALING AND PREVENTION OF ALVEOLAR OSTEITIS IN THE FRAIL AND/OR INSTITUTIONALIZED AGEING ADULT
Haidar, Z. S. (Principal Investigator)
12/10/21 → 12/12/22
Project: RESEARCH
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FONDECYT REGULAR - 1210654: SMALL EXTRACELLULAR VESICLES OBTAINED FROM NEUROPILIN-1+ T REGULATORY CELLS AS A NOVEL TOOL FOR THE INDUCTION OF TRANSPLANTATION TOLERANCE
Pino-Lagos, K. (Principal Investigator) & Wyneken, Ú. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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FONDECYT REGULAR - 1211353: INVESTIGATING THE IMMUNOREGULATORY AND ANTI-RHEUMATOID ARTHRITIS ACTIVITIES OF SMALL EXTRACELLULAR VESICLES-SHUTTLED BIOACTIVE MICRORNA DERIVED FROM GLYCOLYTIC MESENCHYMAL STEM CELL
Luz Crawford, P. A. (Principal Investigator), Khoury, M. (Co-Investigator), Alcayaga-Miranda, F. (Co-Investigator), Elizondo-Vega, R. (Co-Investigator), Altamirano, C. (Co-Investigator) & Nova-Lamperti, E. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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FONDECYT REGULAR - 1211471: THE PATHOGENIC VICIOUS CYCLE BETWEEN PERIODONTITIS AND GESTATIONAL DIABETES MELLITUS: COMMUNICATION VIA BACTERIAL TRANSLOCATION AND EXTRACELLULAR VESICLES
Chaparro, A. (Principal Investigator), Busso, D. (Co-Investigator), Illanes, S. (Co-Investigator), Ramirez Lobos, V. (Co-Investigator), Hernández Ríos, E. (Co-Investigator) & Hoare, A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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FONDECYT REGULAR - 1211749: IMPACT OF HORIZONTAL ARTIFICIAL TRANSFER OF MITOCHONDRIA ON UMBILICAL CORD BLOOD TRANSPLANTATION AND ITS CLINICAL RELEVANCE IN GRAFT VERSUS HOST DISEASE.
Khoury, M. (Principal Investigator), Luz Crawford, P. A. (Co-Investigator), Court, A. C. (Co-Investigator) & Figueroa, F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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FONDECYT REGULAR - 1211384: PRENATAL STRESS: MATERNAL ASTROCYTE-DERIVED EXTRACELLULAR VESICLES AS A NOVEL STRESS-TRANSFER MECHANISM CONTRIBUTING TO ADVERSE OFFSPRING NEURODEVELOPMENT
Batiz, L. F. (Principal Investigator), Nardocci, G. (Co-Investigator), Wyneken, Ú. (Co-Investigator), Illanes, S. (Co-Investigator), J. Monteiro, L. (Co-Investigator) & Caradeux, J. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL
Cuenca, J. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Khoury, M. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & Kurte, M. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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FONDECYT REGULAR - 1211376: INVESTIGATING THE EFFECT OF MAVS-ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRAL-INDUCED ACUTE LUNG INJURY MODEL.
Cuenca, J. (Principal Investigator), Alcayaga-Miranda, F. (Co-Investigator), Khoury, M. (Co-Investigator), Hidalgo, Y. (Co-Investigator) & Kurte, M. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/21 → 31/03/25
Project: RESEARCH
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Franco-Chilean initiative for Intra-Mitochondrial microRNAs as new mediators of mesenchymal stem cells immunoregulatory functions
Luz Crawford, P. A. (Principal Investigator)
1/03/21 → 28/02/25
Project: RESEARCH
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Metabolic reprograming of effector CD4+T cells by mitochondrial mediated-signalling in oral cancer and its effect upon T helper and T-dependent B cell responses
Nova, E. (Principal Investigator) & Luz Crawford, P. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/03/21 → 29/02/24
Project: RESEARCH
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Immunoregulatory and anti-rheumatoid arthritis activities of small extracellular vesicles-shuttled bioactive microRNA derived from glycolytic mesenchymal stem cells
Luz Crawford, P. A. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/03/21 → 29/02/24
Project: RESEARCH
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Generación de un extracto de un alimento andino con propiedades antidiabéticas
Busso, D. (Principal Investigator), Enrione, J. I. (Principal Investigator) & Illanes, S. (Principal Investigator)
1/08/20 → 30/11/20
Project: RESEARCH
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FONDECYT REGULAR - 1201420: Mitochondrial transfer within the osteoarthritic joint: restoration of the dysfunctional stress-response and metabolic pathway in cartilage in-vitro and in an animal model of disease
Figueroa, F. (Principal Investigator), Khoury, M. (Co-Investigator), Luz Crawford, P. A. (Co-Investigator) & Court, A. C. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/20 → 31/03/24
Project: RESEARCH
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FONDECYT REGULAR - 1201851: Role of mesenchymal stem cells in implantation and their contribution to the decidualization disorders present in preeclampsia
Illanes, S. (Principal Investigator), Pino-Lagos, K. (Co-Investigator), J. Monteiro, L. (Co-Investigator) & Acuña, S. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/20 → 31/03/23
Project: RESEARCH
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FONDECYT REGULAR - 1201584: Understanding of shape memory properties of gelatin-cellulose nanocrystal composites through interaction assessments at their interface
Enrione, J. I. (Principal Investigator), Quero, F. (Co-Investigator) & Melo, F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/20 → 31/03/23
Project: RESEARCH
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FONDECYT REGULAR - 1200693: Brain astrocyte-derived extracellular vesicles promote protective Treg induction in the GALT and restore gut tolerance in stressed rats
Wyneken, Ú. (Principal Investigator), Batiz, L. F. (Co-Principal Investigator), Pino-Lagos, K. (Co-Investigator) & Batiz, L. F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/20 → 31/03/24
Project: RESEARCH
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Association between periodontal dysbiosis and immune evasion in gastric cancer
Retamal, I. (Principal Investigator) & Chaparro, A. (Sponsoring Researcher)
5/03/20 → 4/03/22
Project: RESEARCH
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Mitochondrial transfer from mesenchymal stem cells for osteoarthritis treatment
Figueroa, F. (Principal Investigator) & Luz Crawford, P. A. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/03/20 → 28/02/23
Project: RESEARCH
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Lipophilic statins inhibit the exosome-mediated and obesity-induced cancer progression: the relevance of reestablishing natural killer cell immune surveillance to delay recurrence and improve future therapeutic outcomes in high-grade serous ovarian cancer
Cuello, M. (Principal Investigator) & Busso, D. (Co-Investigator)
1/03/20 → 28/02/23
Project: RESEARCH
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Desarrollo de modelo de procesamiento oral in-vitro de adultos mayores y su uso en el estudio de degradación de proteínas vegetales de rápida digestibilidad para promover la síntesis de proteínas musculares
Contardo, I. M. (Principal Investigator) & Enrione, J. I. (Sponsoring Researcher)
1/01/20 → 1/12/20
Project: RESEARCH
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Validación de algoritmo multiparamétrico para la predicción temprana de Diabetes Gestacional mediante marcadores plasmáticos maternos
Illanes, S. (Director), J. Monteiro, L. (Alternate Director), Correa, P. (Co-Investigator) & Monckeberg, M. (Co-Investigator)
1/01/20 → 1/01/23
Project: RESEARCH
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FONDECYT INICIACIÓN - 11190998: UNDERSTANDING THE CONTRIBUTION OF A LNCRNA DURING THE EARLY STAGES OF OSTEOGENESIS
Nardocci, G. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/11/19 → 31/10/22
Project: RESEARCH
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Estudio de Carga de Enfermedad Atribuible al Actual Nivel de Exposición a Yodo y Ácido Fólico en Chile: Identificación de Niveles Óptimos de Fortificación Nacional y Recomendaciones para una Nueva Política Integrada de Micronutrientes
Mosso, L. (Principal Investigator) & Busso, D. (Co-Investigator)
1/10/19 → 31/05/22
Project: RESEARCH
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"ALERT-NeurodEV”: Early detection of prenatal stress-induced neurodevelopmental changes by umbilical cord blood biomarkers
Batiz, L. F. (Principal Investigator) & Illanes, S. (Co-Investigator)
Universidad de los Andes Chile
1/06/19 → 30/09/19
Project: RESEARCH
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FONDECYT REGULAR - 1191375: Starch-cellulose composites with controlled crystallinity: towards the better understanding of structural features and enzymatic hydrolysis
Díaz Calderón, P. C. (Principal Investigator), Melo, F. (Co-Investigator) & Quero, F. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/19 → 31/03/22
Project: RESEARCH
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Regulation of mesenchymal stem cell metabolic status to increase their immunosuppresive potential
Luz Crawford, P. A. (Principal Investigator)
1/04/19 → 31/03/21
Project: RESEARCH
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FONDECYT REGULAR - 1190411: Investigating the anti-angiogenic effect of exosome-mediated delivery of functionally active miRNA-149-3p,145-5p and 6131 to tumor tissue
Alcayaga-Miranda, F. (Principal Investigator), Cuenca, J. (Co-Investigator), Khoury, M. (Co-Investigator) & Pino-Lagos, K. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/19 → 15/04/23
Project: RESEARCH
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FONDECYT POSTDOCTORADO - 3190646: ALFA-SNAP REGULA EL BALANCE ENTRE AUTORENOVACIÓN/PROLIFERACIÓN Y DIFERENCIACIÓN DE CÉLULAS MADRE NEURALES, MODULANDO LA ACTIVIDAD AMPK Y LA HOMEOSTASIS MITOCONDRIAL
Henzi, R. (Postdoctoral Researcher) & Batiz, L. F. (Sponsoring Researcher)
Consejo Nacional para Investigaciones Científicas y Tecnológicas
15/03/19 → 14/03/22
Project: RESEARCH
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FONDECYT POSTDOCTORADO - 3190683: PRODUCTION AND CHARACTERIZATION OF ANTIHYPERTENSIVE PEPTIDES FRACTIONATED FROM QUINOA (CHENONOPODIUM QUINOA WILLD.)
Díaz Calderón, P. C. (Sponsoring Researcher) & González-Muñoz, A. (Postdoctoral Researcher)
Consejo Nacional para Investigaciones Científicas y Tecnológicas
15/03/19 → 14/03/23
Project: RESEARCH
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Regulation of mesenchymal stem cells metabolic status to improve their therapeutic potential for arthritis
Luz Crawford, P. A. (Principal Investigator)
1/01/19 → 31/12/20
Project: RESEARCH
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Use of protein biomarkers in plasma-derived extracellular vesicles to improve the diagnosis of bipolar disorder
Wyneken, Ú. (Principal Investigator), Batiz, L. F. (Co-Investigator) & Prieto, M. (Co-Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/01/19 → 1/01/21
Project: RESEARCH
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Undertanding of interfacial interaction in cellulose based biocomposites for applications in food science and nutrition
Enrione, J. I. (Principal Investigator)
1/12/18 → 1/06/20
Project: RESEARCH
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FONDECYT INICIACIÓN - 11180291: ACUTE VOCAL FOLD INFLAMMATION AFTER PHONOTRAUMA: A NEW TREATMENT BASED ON MECHANICAL TISSUE MOBILIZATION
Guzmán Noriega, M. A. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/11/18 → 31/10/21
Project: RESEARCH
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FONDECYT INICIACIÓN - 11181249: THE ROLE OF FOXM1 IN EARLY PREECLAMPSIA-RELATED EVENTS
J. Monteiro, L. (Principal Investigator)
Agencia Nacional de Investigación y Desarrollo
1/11/18 → 16/05/23
Project: RESEARCH
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CONTRATOS TECNOLOGICOS - 18COTE-89695: SEDA DENTAL NANO-MEDICADA CON ANTIMICROBIANOS/NP-CU PARA LA PREVENCIÓN/MANEJO DE LA CARIES DENTAL Y ENFERMEDAD PERIODONTAL
Haidar, Z. S. (Principal Investigator)
31/05/18 → 30/11/21
Project: RESEARCH
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FONDECYT REGULAR - 1181365: EFFECT OF GENETIC VARIANTS IN CALCIUM CHANNEL GENES ON CARDIAC FUNCTION IN BIPOLAR DISORDER
Batiz, L. F. (Co-Principal Investigator), Prieto, M. (Principal Investigator), De León, A. (Co-Investigator), Veas, N. (Co-Investigator), Cavada, G. (Co-Investigator) & Fullerton, C. (Co-Investigator)
Agencia Nacional de Investigación y Desarrollo
1/04/18 → 31/03/23
Project: RESEARCH