Doctorado en Biomedicina

Projects

Projects per year 2000 2012 2014 2019 2020 2021 2031

• 23 Active
• 47 Finished

Projects per year

Search results

• Active

  Glycostem-sev: generación de un producto acelular basado en nanovesículas extracelulares derivadas de células madre mesenquimales inducidas hacia un metabolismo glicolítico para el tratamiento de la osteoartritis

  Luz Crawford, P. A., Alcayaga-Miranda, F., Elizondo-Vega, R. J., Espinoza, F. & Matas, J.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/21 → 30/11/23

  Project: Research

• Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT)

  Khoury, M., Alcayaga-Miranda, F., Cuenca, J., Acevedo, J. P., Figueroa, F., Luz Crawford, P. A., Wyneken, Ú., Illanes, S., Batiz, L. F., Busso, D., J. Monteiro, L., Nardocci, G., Enrione, J., Espinoza, F., Valenzuela Bravo, M. T. & Prieto, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/21 → 31/10/26

  Project: Research

• INVESTIGATING THE EFFECT OF MAVS ENRICHED MITOCHONDRIAL TRANSPLANTATION ON INTRACELLULAR ANTIVIRAL IMMUNITY AND THEIR RESTORATIVE AND IMMUNOMODULATORY EFFECTS IN A VIRALINDUCED ACUTE LUNG INJURY MODEL

  Cuenca, J., Alcayaga-Miranda, F., Khoury, M., Hidalgo, Y. & Kurte, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/21 → 31/03/25

  Project: Research

• Immunoregulatory and anti-rheumatoid arthritis activities of small extracellular vesicles-shuttled bioactive microRNA derived from glycolytic mesenchymal stem cells

  Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/21 → 29/02/24

  Project: Research

• Franco-Chilean initiative for Intra-Mitochondrial microRNAs as new mediators of mesenchymal stem cells immunoregulatory functions

  Luz Crawford, P. A.

  1/03/21 → 28/02/25

  Project: Research

• Impact of Horizontal artificial Transfer of Mitochondria on umbilical cord blood transplantation and its clinical relevance in Graft versus Host Disease

  Khoury, M. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/21 → 29/02/24

  Project: Research

• Metabolic reprograming of effector CD4+T cells by mitochondrial mediated-signalling in oral cancer and its effect upon T helper and T-dependent B cell responses

  Nova, E. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/21 → 29/02/24

  Project: Research

• The pathogenic vicious cycle between periodontitis and gestational diabetes mellitus: communication via bacterial translocation and extracellular vesicles

  Chaparro, A. & Busso, D.

  1/03/21 → 29/02/24

  Project: Research

• Prenatal stress: Maternal astrocyte-derived extracellular vesicles as a novel stress-transfer mechanism contributing to adverse offspring neurodevelopment

  Batiz, L. F., Nardocci, G., Wyneken, Ú., Illanes, S., J. Monteiro, L. & Caradeux, J.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/21 → 1/01/25

  Project: Research

• Brain astrocyte-derived extracellular vesicles promote protective Treg induction in the GALT and restore gut tolerance in stressed rats

  Wyneken, Ú. & Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/20 → 31/03/24

  Project: Research

• Understanding of shape memory properties of gelatin-cellulose nanocrystal composites through interaction assessments at their interface

  Enrione, J.

  1/04/20 → 31/03/23

  Project: Research

• Mitochondrial transfer within the osteoarthritic joint: restoration of the dysfunctional stress-response and metabolic pathway in cartilage in-vitro and in an animal model of disease

  Figueroa, F.

  1/04/20 → 31/03/24

  Project: Research

• Role of mesenchymal stem cells in implantation and their contribution to the decidualization disorders present in preeclampsia

  Illanes, S., Pino-Lagos, K., J. Monteiro, L. & Acuña, S.

  1/04/20 → 31/03/23

  Project: Research

• Mitochondrial transfer from mesenchymal stem cells for osteoarthritis treatment

  Figueroa, F. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/03/20 → 28/02/23

  Project: Research

• Lipophilic statins inhibit the exosome-mediated and obesity-induced cancer progression: the relevance of reestablishing natural killer cell immune surveillance to delay recurrence and improve future therapeutic outcomes in high-grade serous ovarian cancer

  Cuello, M. & Busso, D.

  1/03/20 → 28/02/23

  Project: Research

• Validación de algoritmo multiparamétrico para la predicción temprana de Diabetes Gestacional mediante marcadores plasmáticos maternos

  Illanes, S., J. Monteiro, L., Correa, P. & Monckeberg, M.

  1/01/20 → 1/01/23

  Project: Research

• Understanding the contribution of a lncRNA during the early stages of osteogenesis

  Nardocci, G.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/11/19 → 31/10/22

  Project: Research

• Estudio de Carga de Enfermedad Atribuible al Actual Nivel de Exposición a Yodo y Ácido Fólico en Chile: Identificación de Niveles Óptimos de Fortificación Nacional y Recomendaciones para una Nueva Política Integrada de Micronutrientes

  Mosso, L. & Busso, D.

  1/10/19 → 31/05/22

  Project: Research

• Investigating the anti-angiogenic effect of exosome-mediated delivery of functionally active miRNA-149-3p,145-5p and 6131 to tumor tissue

  Alcayaga-Miranda, F. & Cuenca, J.

  1/04/19 → 15/04/23

  Project: Research

• Starch-cellulose composites with controlled crystallinity: towards the better understanding of structural features and enzymatic hydrolysis

  Díaz Calderón, P.

  1/04/19 → 15/04/22

  Project: Research

• The role of FOXM1 in early preeclampsia-related events

  J. Monteiro, L.

  1/11/18 → 14/11/22

  Project: Research

• Effect of genetic variants in calcium channel genes on cardiac function in bipolar disorder

  Batiz, L. F. & Prieto, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/18 → 15/04/22

  Project: Research

• Millennium Institute on Immunology and Immunotherapy (IMII)

  Kalergis, A. M. & Luz Crawford, P. A.

  1/09/11 → 1/09/31

  Project: Research

  • Allergy and Immunology 100%
  • Immunotherapy 41%
  • Endocrine System Diseases 31%
  • Autoimmunity 22%
  • Vaccines 17%
• Finished

  Generación de un extracto de un alimento andino con propiedades antidiabéticas

  Busso, D., Enrione, J. & Illanes, S.

  1/08/20 → 30/11/20

  Project: Research

• Mirando al futuro: Efectos del estrés prenatal y perinatal asociado a la pandemia COVID-19 en el neurodesarrollo de niñas y niños de Chile

  Batiz, L. F., Illanes, S., J. Monteiro, L., Tenorio, M., Avaria, M. D. L. A., Nardocci, G., Nuñez, M. I. & Peñailillo, R.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  6/07/20 → 1/01/22

  Project: Research

• Association between periodontal dysbiosis and immune evasion in gastric cancer

  Retamal, I. & Chaparro, A.

  5/03/20 → 4/03/22

  Project: Research

• Desarrollo de modelo de procesamiento oral in-vitro de adultos mayores y su uso en el estudio de degradación de proteínas vegetales de rápida digestibilidad para promover la síntesis de proteínas musculares

  Contardo, I. & Enrione, J.

  Universidad de los Andes

  1/01/20 → 1/12/20

  Project: Research

• "ALERT-NeurodEV”: Early detection of prenatal stress-induced neurodevelopmental changes by umbilical cord blood biomarkers

  Batiz, L. F. & Illanes, S.

  Universidad de los Andes Chile

  1/06/19 → 30/09/19

  Project: Research

• Regulation of mesenchymal stem cell metabolic status to increase their immunosuppresive potential

  Luz Crawford, P. A.

  1/04/19 → 31/03/21

  Project: Research

• Alfa-SNAP regula el balance entre autorenovación/proliferación y diferenciación de células madre neurales, modulando la actividad AMPK y la homeostasis mitocondrial

  Henzi, R. & Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/19 → 1/01/22

  Project: Research

• Use of protein biomarkers in plasma-derived extracellular vesicles to improve the diagnosis of bipolar disorder

  Wyneken, Ú., Batiz, L. F. & Prieto, M.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/19 → 1/01/21

  Project: Research

• Regulation of mesenchymal stem cells metabolic status to improve their therapeutic potential for arthritis

  Luz Crawford, P. A.

  1/01/19 → 31/12/20

  Project: Research

• Undertanding of interfacial interaction in cellulose based biocomposites for applications in food science and nutrition

  Enrione, J.

  1/12/18 → 1/06/20

  Project: Research

• Maternal brain-to-fetal brain communication under stress conditions: role of astrocyte derived-extracellular vesicles

  Batiz, L. F., Illanes, S. & Wyneken, Ú.

  Wayne State University

  1/01/18 → 1/01/20

  Project: Research

• Desarrollo y validación de un producto celular alogénico derivado de células madre estromales para su uso en síndrome de distrés respiratorio agudo

  Cuenca, J. & Alcayaga-Miranda, F.

  23/06/17 → 22/06/19

  Project: Research

• Functional impact of MSC mitochondrial transfer to T lymphocytes and its clinical relevance in a Graft versus Host Disease

  Khoury, M. & Luz Crawford, P. A.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/04/17 → 15/04/21

  Project: Research

• Effect of cellulose nanofibers on thermomechanical and shape memory properties of salmon gelatine based composites

  Enrione, J.

  1/04/17 → 15/04/20

  Project: Research

• Tecnologías de Imágenes por Resonancia Magnética para enfermedades asociadas a la vejez: cerebro, corazón y vasos

  Irarrázaval, P. & Busso, D.

  1/03/15 → 28/02/18

  Project: Research

• Center for Interdisciplinary Studies on the Nervous System (CISNe) // Centro Interdisciplinario de estudios del Sistema Nervioso (CISNe)

  Batiz, L. F.

  Universidad Austral de Chile

  1/01/15 → 1/01/18

  Project: Research

• Desarrollo de una plataforma de análisis de interacciones moleculares para el fortalecimiento de la investigación en ciencias biomédicas y biotecnológicas en la UACh

  Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/15 → 1/01/16

  Project: Research

• Fundamentals of natural polymers and composites for applications in food science and technology, and tissue engineering

  Enrione, J.

  1/12/14 → 1/06/16

  Project: Research

• Structural modification of starch matrices by addition of bacterial cellulose: towards the design of food materials with tailored functional properties.

  Díaz Calderón, P.

  15/11/14 → 30/10/16

  Project: Research

• Fragility studies of gelatine-oligosacharides hydrogels approaching the glass transition temperature

  Enrione, J.

  15/03/14 → 15/03/17

  Project: Research

• Cholesterol is bad for eggs as much as eggs are bad for cholesterol

  Busso, D.

  1/03/14 → 28/02/15

  Project: Research

• Impact of high density lipoprotein metabolism in mouse oocyte and embryo physiology: underlying mechanisms, pathological implications and potential interventions

  Busso, D.

  1/03/14 → 28/02/17

  Project: Research

• Canonical and non-canonical roles of alpha-SNAP in the pathogenesis of neurodevelopmental disorders: focur on modulation of autophagy and AMPK signaling

  Batiz, L. F.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/01/14 → 1/01/18

  Project: Research

• Predicción de Diabetes Gestacional durante el primer trimestre de embarazo mediante modelo multiparamétrico

  Illanes, S. & Correa, P.

  1/12/13 → 1/12/15

  Project: Research

• The role of the aromatase pathway in 2-methoxyestradiol synthesis in the pathogenesis of preeclampsia

  J. Monteiro, L. & Illanes, S.

  2/11/13 → 30/11/17

  Project: Research

• Reclutamiento de modificadores epigenéticos mediado por lncRNAs en la regulación transcripcional del gen Runx2

  Nardocci, G.

  Agencia Nacional de Investigación y Desarrollo (ANID), Chile

  1/10/13 → 1/01/16

  Project: Research

• Fortalecimiento de la Docencia e Investigación en Estructuras en Alimentos y su Efecto en la Biodisponibilidad de Nutrientes

  Díaz Calderón, P.

  1/09/13 → 1/09/16

  Project: Research